Effects of a low-doses treatment with cuprum on neostigmine digestive action in female mice

1991 ◽  
Vol 24 (3) ◽  
pp. 231-233 ◽  
Author(s):  
R. Santini ◽  
M. Tessier ◽  
P. Belon
Keyword(s):  
Low Doses ◽  
Female Mice

scholarly journals Female mice exposed to low doses of dioxin during pregnancy and lactation have increased susceptibility to diet-induced obesity and diabetes

2020 ◽  
Vol 42 ◽  
pp. 101104 ◽  
Author(s):  
Myriam P. Hoyeck ◽  
Rayanna C. Merhi ◽  
Hannah L. Blair ◽  
C. Duncan Spencer ◽  
Mikayla A. Payant ◽  
...  
Keyword(s):  
Low Doses ◽  
Female Mice ◽  
Diet Induced Obesity ◽  
Obesity And Diabetes ◽  
Pregnancy And Lactation ◽  
Increased Susceptibility

Chemical Modulation of 3-Methylindole Toxicosis in Mice: Effect on Bronchiolar and Olfactory Mucosal Injury

1986 ◽  
Vol 23 (5) ◽  
pp. 563-570 ◽  
Author(s):  
M. A. M. Turk ◽  
W. Flory ◽  
W. G. Henk
Keyword(s):  
Mucosal Injury ◽  
Low Doses ◽  
Mixed Function Oxidase ◽  
Male And Female ◽  
Oxidase System ◽  
Pulmonary Lesions ◽  
Epithelial Damage ◽  
Female Mice ◽  
Mixed Function Oxidase System ◽  
Chemical Modulation

C57BL/6N mice were treated to induce tolerance, to modulate the mixed function oxidase system or to deplete glutathione (GSH) before injection with 400 mg 3-methylindole (3MI)/kg. Effect of pretreatment was determined by histologic comparison of pulmonary and nasal lesions 24 hours after 3 MI. β-Naphthoflavone and 3MI pretreatment significantly decreased 3MI-induced bronchiolar epithelial damage in male and female mice, while phenobarbital protection was significant only in female mice. Only β-naphthoflavone decreased nasal olfactory epithelial damage. Pretreatment with piperonyl butoxide, SKF 525-A, or α-naphthoflavone had no significant effect on development of lesions. Diethylmaleate pretreatment significantly increased mortality and bronchiolar damage in both sexes. Significant differences between male and female mice were not detected in any group. The results suggest that pretreatment with low doses of 3MI or induction of cytochrome P-448 or P-450 protects against 3MI toxicosis while GSH depletion increases mortality and pulmonary lesions.

scholarly journals Prenatal Exposure to Low Doses of Bisphenol A Increases Pituitary Proliferation and Gonadotroph Number in Female Mice Offspring at Birth1

2012 ◽  
Vol 87 (4) ◽  
Author(s):  
Katherine E. Brannick ◽  
Zelieann R. Craig ◽  
Ashley D. Himes ◽  
Jackye R. Peretz ◽  
Wei Wang ◽  
...  
Keyword(s):  
Bisphenol A ◽  
Prenatal Exposure ◽  
Low Doses ◽  
Female Mice

Reproductive toxicity assessment of Senecio scandens extract in kunming mice

2019 ◽  
Author(s):  
Lartey Kwame Ayisi ◽  
Nie Fang-Hong ◽  
Yu Zeng-Jie ◽  
Lin Hong-Ying ◽  
Yang Fan ◽  
...  
Keyword(s):  
Reproductive Toxicity ◽  
Assessment Method ◽  
Toxicity Assessment ◽  
Low Doses ◽  
Female Mice ◽  
Three Phase ◽  
Sperm Abnormality ◽  
High Doses ◽  
Dose Response Effect ◽  
Toxicity Effects

This study assessed the effects of Senecio scandens Buch. Ham.extract on reproductive spectrum in female mice using a three phase reproductive assessment method. Sperm abnormality rate was used to evaluate effect on genetic reproductive toxicity. Senecio scandens extract was relatively non-toxic at low doses in all phases of reproduction in female mice. However, it showed a dose-response effect on sperm abnormality rate, and at high doses has the potential to induce genetic reproductive toxicity in male mice. It is suggested that the well-understood pharmacological benefits of S. scandens extract as an herbal medicine far outweigh the minimal reproductive toxicity effects observed in this study.

Perinatal exposure to low doses of tributyltin chloride advances puberty and affects patterns of estrous cyclicity in female mice

2012 ◽  
Vol 27 (11) ◽  
pp. 662-670 ◽  
Author(s):  
Jiliang Si ◽  
Xiaoying Han ◽  
Fengmei Zhang ◽  
Quanbin Xin ◽  
Lihong An ◽  
...  
Keyword(s):  
Perinatal Exposure ◽  
Low Doses ◽  
Female Mice ◽  
Tributyltin Chloride ◽  
Estrous Cyclicity

Effects of low doses of dietary lead on puberty onset in female mice

2004 ◽  
Vol 19 (1) ◽  
pp. 35-41 ◽  
Author(s):  
I. Iavicoli ◽  
G. Carelli ◽  
E.J. Stanek ◽  
N. Castellino ◽  
E.J. Calabrese
Keyword(s):  
Low Doses ◽  
Female Mice ◽  
Puberty Onset
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