GABAmimetic drugs in hyperkinetic involuntary movement disorders and their effects on mental status

1990 ◽  
Vol 21 (3) ◽  
pp. 227-233 ◽  
Author(s):  
C. A. Tamminga ◽  
G. K. Thaker
Keyword(s):  
Mental Status ◽  
Movement Disorders ◽  
Involuntary Movement

Long-Term Results of Cerebellar Chronic Electrostimulation in Involuntary Movement Disorders

1982 ◽  
Vol 45 (3) ◽  
pp. 218-220
Author(s):  
V.A. Fasano ◽  
G. Broggi ◽  
S. Zeme ◽  
G. Lo Russo
Keyword(s):  
Movement Disorders ◽  
Involuntary Movement ◽  
Long Term Results

Movement disorders are associated with schizotypy in unaffected siblings of patients with non-affective psychosis

2011 ◽  
Vol 41 (10) ◽  
pp. 2141-2147 ◽  
Author(s):  
J. P. Koning ◽  
D. E. Tenback ◽  
R. S. Kahn ◽  
M. G. Vollema ◽  
W. Cahn ◽  
...  
Keyword(s):  
Movement Disorders ◽  
Genetic Risk ◽  
Rating Scale ◽  
Involuntary Movement ◽  
Structured Interview ◽  
Healthy Controls ◽  
Vulnerability Factors ◽  
Cross Sectional ◽  
Affective Psychosis ◽  
Cross Sectional Design

BackgroundMovement disorders and schizotypy are both prevalent in unaffected siblings of patients with schizophrenia and both are associated with the risk of developing psychosis or schizophrenia. However, to date there has been no research into the association between these two vulnerability factors in persons with an increased genetic risk profile. We hypothesized that unaffected siblings of patients with non-affective psychosis have more movement disorders and schizotypy than healthy controls and that these co-occur.MethodIn a cross-sectional design we assessed the prevalence and inter-relationship of movement disorders and schizotypy in 115 unaffected siblings (mean age 27 years, 44% males) and 100 healthy controls (mean age 26 years, 51% males). Movement disorders were measured with the Abnormal Involuntary Movement Scale (AIMS), the Unified Parkinson Disease Rating Scale (UPDRS), the Barnes Akathisia Rating Scale (BARS), and one separate item for dystonia. Schizotypy was assessed with the Structured Interview for Schizotypy – Revised (SIS-R).ResultsThere were significant differences in the prevalence of movement disorders in unaffected siblings versus healthy controls (10% v. 1%, p<0.01) but not in the prevalence of schizotypy. Unaffected siblings with a movement disorder displayed significantly more positive and total schizotypy (p=0.02 and 0.03 respectively) than those without. In addition, dyskinesia correlated with positive schizotypy (r=0.51, p=0.02).ConclusionsThe association between movement disorders (dyskinesia in particular) with positive and total schizotypy in unaffected siblings suggests that certain vulnerability factors for psychosis or schizophrenia cluster in a subgroup of subjects with an increased genetic risk of developing the disease.

Involuntary Movements

2020 ◽  
Author(s):  
Hiroshi Shibasaki ◽  
Mark Hallett ◽  
Kailash P Bhatia ◽  
Stephen G. Reich ◽  
Bettina Balint
Keyword(s):  
Clinical Features ◽  
Movement Disorders ◽  
Involuntary Movement ◽  
Current Treatment ◽  
Video Cases ◽  
Visual Appearance ◽  
Involuntary Movements ◽  
Published Paper

This book is aimed at describing clinical features of various kinds of involuntary movements by demonstrating a number of cases on video. Most of the video cases presented in this book were directly observed and studied by at least one of the five authors, and a few cases were from the published paper with permission. The authors also discuss the current consensus about the classification, pathophysiology, and current treatment of each involuntary movement. This book adopts a unique way of looking at movement disorders by considering two aspects of the diagnosis: Axis 1, the phenomenology, and Axis 2, the etiology and/or pathophysiology. The visual appearance of the disorder, as seen on video, is a big part of Axis 1 diagnosis.

scholarly journals Clinical Characteristics of Coronavirus Disease 2019 (COVID-19) among Patients at a Movement Disorders Center

Geriatrics ◽  
2020 ◽  
Vol 5 (3) ◽  
pp. 54
Author(s):  
Joy Antonelle de Marcaida ◽  
Jeffrey Lahrmann ◽  
Duarte Machado ◽  
Lawrence Bluth ◽  
Michelle Dagostine ◽  
...  
Keyword(s):  
Mortality Rate ◽  
Mental Status ◽  
Movement Disorders ◽  
Clinical Characteristics ◽  
Altered Mental Status ◽  
Atypical Parkinsonism ◽  
Health Records ◽  
Telephone Interviews ◽  
Presenting Symptoms ◽  
Idiopathic Parkinson Disease

It is not established whether SARS-CoV-2 (COVID-19) patients with movement disorders, are at greater risk for more serious outcomes than the larger COVID-19 population beyond the susceptibility associated with greater age. We reviewed electronic health records and conducted telephone interviews to collect the demographics and clinical outcomes of patients seen at our Movement Disorders Center who tested positive for COVID-19 from 8 March 2020 through 6 June 2020. Thirty-six patients were identified, 23 men and 13 women, median age of 74.5 years. They primarily carried diagnoses of idiopathic Parkinson disease (n = 22; 61%) and atypical parkinsonism (n = 7; 19%) with the balance having other diagnoses. Twenty-seven patients (75%) exhibited alteration in mental status and fifteen (42%) had abnormalities of movement as common manifestations of COVID-19; in 61% and 31%, respectively, these were the presenting symptoms of the disease. Sixty-seven percent of patients in our cohort required hospitalization, and the mortality rate was 36%. These data demonstrate that in patients with movement disorders, the likelihood of hospitalization and death after contracting COVID-19 was greater than in the general population. Patients with movement disorders frequently presented with altered mental status, generalized weakness, or worsening mobility but not anosmia.

Investigation of the Surgical Target for Alleviation of Involuntary Movement Disorders

1982 ◽  
Vol 45 (3) ◽  
pp. 261-274 ◽  
Author(s):  
R.R. Tasker ◽  
L.W. Organ ◽  
P. Hawrylyshyn
Keyword(s):  
Movement Disorders ◽  
Involuntary Movement
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