Neuropharmacology of anxiolytic drugs: A selected review of the field

1982 ◽  
Vol 2 (S1) ◽  
pp. 1-11 ◽  
Author(s):  
B. E. Leonard
Keyword(s):  
Anxiolytic Drugs

Rate of Prescription of Antidepressant and Anxiolytic Drugs after Cyclone Yasi in North Queensland

2012 ◽  
Vol 27 (6) ◽  
pp. 519-523 ◽  
Author(s):  
Kim Usher ◽  
Lawrence H. Brown ◽  
Petra Buettner ◽  
Beverley Glass ◽  
Helen Boon ◽  
...  
Keyword(s):  
Psychological Symptoms ◽  
Drug Prescription ◽  
Antidepressant Drugs ◽  
Publication Type ◽  
Control Drug ◽  
General Psychological Distress ◽  
Anxiolytic Drugs ◽  
And Gender ◽  
Gender Groups ◽  
Rule Out

AbstractIntroductionThe need to manage psychological symptoms after disasters can result in an increase in the prescription of psychotropic drugs, including antidepressants and anxiolytics. Therefore, an increase in the prescription of antidepressants and anxiolytics could be an indicator of general psychological distress in the community.PurposeThe purpose of this study was to determine if there was a change in the rate of prescription of antidepressant and anxiolytic drugs following Cyclone Yasi.MethodsA quantitative evaluation of new prescriptions of antidepressants and anxiolytics was conducted. The total number of new prescriptions for these drugs was calculated for the period six months after the cyclone and compared with the same six month period in the preceding year. Two control drugs were also included to rule out changes in the general rate of drug prescription in the affected communities.ResultsAfter Cyclone Yasi, there was an increase in the prescription of antidepressant drugs across all age and gender groups in the affected communities except for males 14-54 years of age. The prescription of anxiolytic drugs decreased immediately after the cyclone, but increased by the end of the six-month post-cyclone period. Control drug prescription did not change.ConclusionThere was a quantifiable increase in the prescription of antidepressant drugs following Cyclone Yasi that may indicate an increase in psychosocial distress in the community.UsherK, BrownLH, BuettnerP, GlassB, BoonH, WestC, GrassoJ, Chamberlain-SalaunJ, WoodsC. Rate of prescription of antidepressant and anxiolytic drugs after Cyclone Yasi in North Queensland. Prehosp Disaster Med. 2012;27(6):1-5.

Discontinued anxiolytic drugs (2009 – 2014)

2015 ◽  
Vol 24 (4) ◽  
pp. 557-573 ◽  
Author(s):  
Roberto Mandrioli ◽  
Laura Mercolini
Keyword(s):  
Anxiolytic Drugs

Inhibition of endocannabinoid neuronal uptake and hydrolysis as strategies for developing anxiolytic drugs

2014 ◽  
Vol 25 (5 and 6) ◽  
pp. 425-433 ◽  
Author(s):  
Luara A. Batista ◽  
Pedro H. Gobira ◽  
Thercia G. Viana ◽  
Daniele C. Aguiar ◽  
Fabricio A. Moreira
Keyword(s):  
Neuronal Uptake ◽  
Anxiolytic Drugs

Anxiolytic Drugs

Psychiatry ◽  
2008 ◽  
pp. 2223-2253
Author(s):  
Deidre M. Edwards ◽  
Kathryn L. Hale ◽  
Rachel E. Maddux ◽  
Mark Hyman Rapaport
Keyword(s):  
Anxiolytic Drugs

scholarly journals Medications for Anxiety: A Drug utilization study in Psychiatry Inpatients from a Tertiary Care Centre of Western Nepal

1970 ◽  
Vol 1 (4) ◽  
pp. 119-125 ◽  
Author(s):  
Indrajit Banerjee ◽  
Bedanta Roy ◽  
Brijesh Sathian ◽  
Indraneel Banerjee ◽  
Sai Sailesh Kumar ◽  
...  
Keyword(s):  
Treatment Guidelines ◽  
Physical Dependence ◽  
Tertiary Care ◽  
Psychiatric Inpatient ◽  
Common Disease ◽  
Utilization Pattern ◽  
Tertiary Care Centre ◽  
Prescribing Pattern ◽  
Study Results ◽  
Anxiolytic Drugs

Background   Anxiety is the most widespread psychiatric disorder and generalized anxiety disorder is the most common disease seen in the primary care setting. Currently there are a number of anxiolytic drugs commercially available in the market for treatment of these disorders such as Benzodiazepines like Diazepam, Chlordiazepoxide, Alprazolam, Betablockers like Propranolol and H1 Antihistaminics like Hydroxyzine. Some of the newer anxiolytics like Buspirone in Azapirone group is marketed as better anxiolytic drug than the traditional drugs.  Buspirone is promoted as a better drug for anxiety, as it does not cause any sedation, tolerance or physical dependence. A need for study further increases as there is no sufficient data on utilization pattern of anxiolytics on Nepalese population. This is the first study done in the utilization pattern of anxiolytic drugs in inpatient in Nepal.  Methods This is an observational study undertaken between 1st October 2009 and 31st March 2010 at the Psychiatric inpatient Department of Manipal Teaching Hospital. The prescribing pattern of Anxiolytic drugs was measured. Out of a total of 240 cases who were admitted to psychiatry inpatient ward, 38 cases have received Anxiolytic drugs. Those who were critically ill with anxiety were included in the study.  Results Out of 240 cases who were admitted to psychiatry inpatient, 130 were male patients (54.2%), 95% CI [47.9,60.5] and the rest were female patients (45.8%), CI [39.5,52.1] . In 38 cases of anxiety, the age of the patient <40 years 89.5% and >40 years 10.5%. Anxiety was more common in females 71.1% than in males 28.9%. 68.4% of the patients were unemployed whereas only 31.6% of the patients were employed. 78.9% of the drugs were prescribed by trade name. Among the anxiolytics, the commonest drug prescribed was Alprazolam (50%), followed by Clonazepam (31.6%), Chlordiazepoxide (15.8%) and Lorazepam (2.6%). Conclusion Utilization patterns of drugs for anxiolytics were according to treatment guidelines and suggested a trend towards the use of shorter acting Benzodiazepines such as Alprazolam. Continuous and prolonged use of longer acting Benzodiazepines has resulted in dependence and may have withdrawal symptoms when the dosage of these drugs is reduced or treatment is stopped.http://dx.doi.org/10.3126/nje.v1i4.5753 Nepal Journal of Epidemiology 2011;1(4):119-125

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