Design, synthesis, biological evaluation, and molecular docking of new benzofuran and indole derivatives as tubulin polymerization inhibitors

Drug Development Research ◽

10.1002/ddr.21880 ◽

2021 ◽

Author(s):

Naglaa F. El‐Sayed ◽

Marwa El‐Hussieny ◽

Ewies F. Ewies ◽

Mohamed F. El Shehry ◽

Hanem M. Awad ◽

...

Keyword(s):

Molecular Docking ◽

Biological Evaluation ◽

Tubulin Polymerization ◽

Indole Derivatives ◽

Design Synthesis ◽

Tubulin Polymerization Inhibitors

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(E)-N-Aryl-2-oxo-2-(3,4,5-trimethoxyphenyl)acetohydrazonoyl cyanides as tubulin polymerization inhibitors: Structure-based bioisosterism design, synthesis, biological evaluation, molecular docking and in silico ADME prediction

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2018.09.004 ◽

2018 ◽

Vol 28 (20) ◽

pp. 3350-3355 ◽

Cited By ~ 3

Author(s):

Guangcheng Wang ◽

Zhiyun Peng ◽

Shanshan Peng ◽

Jie Qiu ◽

Yongjun Li ◽

...

Keyword(s):

Molecular Docking ◽

In Silico ◽

Biological Evaluation ◽

Tubulin Polymerization ◽

Design Synthesis ◽

Adme Prediction ◽

In Silico Adme Prediction ◽

Tubulin Polymerization Inhibitors

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Design, synthesis, biological evaluation and molecular docking studies of new chalcone derivatives containing diaryl ether moiety as potential anticancer agents and tubulin polymerization inhibitors

Bioorganic Chemistry ◽

10.1016/j.bioorg.2019.103565 ◽

2020 ◽

Vol 95 ◽

pp. 103565 ◽

Cited By ~ 7

Author(s):

Guangcheng Wang ◽

Wenjing Liu ◽

Zipeng Gong ◽

Yong Huang ◽

Yongjun Li ◽

...

Keyword(s):

Molecular Docking ◽

Anticancer Agents ◽

Docking Studies ◽

Biological Evaluation ◽

Tubulin Polymerization ◽

Design Synthesis ◽

Molecular Docking Studies ◽

Chalcone Derivatives ◽

Diaryl Ether ◽

Tubulin Polymerization Inhibitors

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Design, Synthesis and Biological Evaluation of 1,4-Disubstituted-3,4-dihydroisoquinoline Compounds as New Tubulin Polymerization Inhibitors

International Journal of Molecular Sciences ◽

10.3390/ijms160510173 ◽

2015 ◽

Vol 16 (12) ◽

pp. 10173-10184 ◽

Cited By ~ 1

Author(s):

Ling Zhang ◽

Yunlong Song ◽

Jingjing Huang ◽

Jia Liu ◽

Wenwen Zhu ◽

...

Keyword(s):

Biological Evaluation ◽

Tubulin Polymerization ◽

Design Synthesis ◽

Tubulin Polymerization Inhibitors ◽

Synthesis And Biological Evaluation

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Design, Synthesis and Biological Evaluation of Novel Acridine and Quinoline Derivatives as Tubulin Polymerization Inhibitors with Anticancer Activities

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2021.116376 ◽

2021 ◽

pp. 116376

Author(s):

Yichang Ren ◽

Yong Ruan ◽

Binbin Cheng ◽

Ling Li ◽

Jin Liu ◽

...

Keyword(s):

Biological Evaluation ◽

Tubulin Polymerization ◽

Quinoline Derivatives ◽

Anticancer Activities ◽

Design Synthesis ◽

Tubulin Polymerization Inhibitors ◽

Synthesis And Biological Evaluation

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3,5-Diaryl-1H-pyrazolo[3,4-b]pyridines as potent tubulin polymerization inhibitors: Rational design, synthesis and biological evaluation

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2018.12.053 ◽

2019 ◽

Vol 168 ◽

pp. 426-435 ◽

Cited By ~ 14

Author(s):

Min'an Zhai ◽

Shiyuan Liu ◽

Meiqi Gao ◽

Long Wang ◽

Jun Sun ◽

...

Keyword(s):

Rational Design ◽

Biological Evaluation ◽

Tubulin Polymerization ◽

Design Synthesis ◽

Tubulin Polymerization Inhibitors ◽

Synthesis And Biological Evaluation

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Novel Pyrazolines and Benzothiazepines as Tubulin Polymerization Inhibitors: Synthesis, Biological Evaluation, and Molecular Docking

Heterocycles ◽

10.3987/com-21-14578 ◽

2022 ◽

Vol 104 (3) ◽

Author(s):

Alaadin E. Sarhan ◽

Ashraf A. Sediek ◽

Nagy M. Khalifa ◽

Essam Ezzeldin

Keyword(s):

Molecular Docking ◽

Biological Evaluation ◽

Tubulin Polymerization ◽

Tubulin Polymerization Inhibitors

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Synthesis, biological evaluation, and molecular docking studies of novel 1-benzene acyl-2-(1-methylindol-3-yl)-benzimidazole derivatives as potential tubulin polymerization inhibitors

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2015.05.021 ◽

2015 ◽

Vol 99 ◽

pp. 125-137 ◽

Cited By ~ 25

Author(s):

Yan-Ting Wang ◽

Ya-Juan Qin ◽

Na Yang ◽

Ya-Liang Zhang ◽

Chang-Hong Liu ◽

...

Keyword(s):

Molecular Docking ◽

Docking Studies ◽

Biological Evaluation ◽

Benzimidazole Derivatives ◽

Tubulin Polymerization ◽

Molecular Docking Studies ◽

Tubulin Polymerization Inhibitors

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Design, synthesis and biological evaluation of novel vicinal diaryl-substituted 1H-Pyrazole analogues of combretastatin A-4 as highly potent tubulin polymerization inhibitors

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2019.111577 ◽

2019 ◽

Vol 181 ◽

pp. 111577 ◽

Cited By ~ 8

Author(s):

Romeo Romagnoli ◽

Paola Oliva ◽

Maria Kimatrai Salvador ◽

Maria Encarnacion Camacho ◽

Chiara Padroni ◽

...

Keyword(s):

Biological Evaluation ◽

Tubulin Polymerization ◽

Design Synthesis ◽

Tubulin Polymerization Inhibitors ◽

Synthesis And Biological Evaluation

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Design, synthesis, in vitro and in vivo biological evaluation of 2-amino-3-aroylbenzo[b]furan derivatives as highly potent tubulin polymerization inhibitors

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2020.112448 ◽

2020 ◽

Vol 200 ◽

pp. 112448 ◽

Cited By ~ 2

Author(s):

Paola Oliva ◽

Romeo Romagnoli ◽

Stefano Manfredini ◽

Andrea Brancale ◽

Salvatore Ferla ◽

...

Keyword(s):

Biological Evaluation ◽

Tubulin Polymerization ◽

Furan Derivatives ◽

Design Synthesis ◽

Tubulin Polymerization Inhibitors

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Design, synthesis and biological evaluation of novel 5,6,7-trimethoxy-N-aryl-2-styrylquinolin-4-amines as potential anticancer agents and tubulin polymerization inhibitors

Bioorganic Chemistry ◽

10.1016/j.bioorg.2020.103711 ◽

2020 ◽

Vol 98 ◽

pp. 103711 ◽

Cited By ~ 1

Author(s):

Salimeh Mirzaei ◽

Farhad Eisvand ◽

Farzin Hadizadeh ◽

Fatemeh Mosaffa ◽

Ali Ghasemi ◽

...

Keyword(s):

Anticancer Agents ◽

Biological Evaluation ◽

Tubulin Polymerization ◽

Design Synthesis ◽

Tubulin Polymerization Inhibitors ◽

Synthesis And Biological Evaluation

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