Antidepressant-Like Activity of Agomelatine in the Mouse Unpredictable Chronic Mild Stress Model

2013 ◽  
Vol 74 (3) ◽  
pp. 203-215 ◽  
Author(s):  
Oguz Mutlu ◽  
Esen Gumuslu ◽  
Guner Ulak ◽  
Ipek Komsuoglu Celikyurt ◽  
Furuzan Akar ◽  
...  
Keyword(s):  
Chronic Mild Stress ◽  
Mild Stress ◽  
Stress Model ◽  
Unpredictable Chronic Mild Stress

scholarly journals Utility of the chronic unpredictable mild stress model in research on new antidepressants

2014 ◽  
Vol 27 (2) ◽  
pp. 97-101 ◽  
Author(s):  
Karolina Pekala ◽  
Barbara Budzynska ◽  
Grazyna Biala
Keyword(s):  
Depressive Disorders ◽  
Prolonged Exposure ◽  
Chronic Mild Stress ◽  
Depressive Illness ◽  
Accurate Diagnosis ◽  
Mild Stress ◽  
Stress Model ◽  
Chronic Unpredictable Mild Stress ◽  
Unpredictable Chronic Mild Stress ◽  
Animal Model Of Depression

Abstract Unpredictable chronic mild stress model was developed as an animal model of depression more than 20 years ago. Essential for this model is that after prolonged exposure of tested animals to a series of unpredictable mild stressors, a condition similar to anhedonia develops, which is observed in the majority of depressive disorders. Unpredictable chronic mild stress model is used nowadays in numerous studies related to the neurobiological and biochemical changes associated with depressive illness. Their results confirm that chronic unpredictable mild stress induces in tested animals a number of changes, which reflect those seen in depressive disorders. Because the effects of unpredictable chronic mild stress can be used in a more accurate diagnosis of the pathophysiology of depressive illness and expand knowledge of its pharmacotherapy, therefore research in this area has been continued all the time.

The Link Between Unpredictable Chronic Mild Stress Model for Depression and Vascular Inflammation?

Inflammation ◽  
2014 ◽  
Vol 37 (5) ◽  
pp. 1432-1438 ◽  
Author(s):  
Tuğçe Demirtaş ◽  
Tijen Utkan ◽  
Ayşe Karson ◽  
Yusufhan Yazır ◽  
Dilek Bayramgürler ◽  
...  
Keyword(s):  
Vascular Inflammation ◽  
Chronic Mild Stress ◽  
Mild Stress ◽  
Stress Model ◽  
Unpredictable Chronic Mild Stress

Antidepressant-like effects of the saponins extracted from Chaihu-jia-longgu-muli-tang in a rat unpredictable chronic mild stress model

Fitoterapia ◽  
2012 ◽  
Vol 83 (1) ◽  
pp. 93-103 ◽  
Author(s):  
Lu-Fan Li ◽  
Jie Lu ◽  
Xiu-Min Li ◽  
Chang-Liang Xu ◽  
Jie Yang ◽  
...  
Keyword(s):  
Chronic Mild Stress ◽  
Mild Stress ◽  
Stress Model ◽  
Unpredictable Chronic Mild Stress

Fluoxetine Effect on Aortic Nitric Oxide-Dependent Vasorelaxation in the Unpredictable Chronic Mild Stress Model of Depression in Mice

2012 ◽  
Vol 74 (1) ◽  
pp. 63-72 ◽  
Author(s):  
Elsa Isingrini ◽  
Catherine Belzung ◽  
Jean-Louis Freslon ◽  
Marie-Christine Machet ◽  
Vincent Camus
Keyword(s):  
Nitric Oxide ◽  
Chronic Mild Stress ◽  
Mild Stress ◽  
Stress Model ◽  
Unpredictable Chronic Mild Stress

Altered aortic vascular reactivity in the unpredictable chronic mild stress model of depression in mice

2011 ◽  
Vol 103 (5) ◽  
pp. 540-546 ◽  
Author(s):  
Elsa Isingrini ◽  
Alexandre Surget ◽  
Catherine Belzung ◽  
Jean-Louis Freslon ◽  
Jefferson Frisbee ◽  
...  
Keyword(s):  
Vascular Reactivity ◽  
Chronic Mild Stress ◽  
Mild Stress ◽  
Stress Model ◽  
Unpredictable Chronic Mild Stress ◽  
Aortic Vascular Reactivity

scholarly journals Antidepressant-Like Activity of Agomelatine in the Mouse Unpredictable Chronic Mild Stress Model

2013 ◽  
Vol 74 (5) ◽  
pp. 340-340
Author(s):  
Oguz Mutlu ◽  
Esen Gumuslu ◽  
Guner Ulak ◽  
Ipek Komsuoglu Celikyurt ◽  
Furuzan Akar ◽  
...  
Keyword(s):  
Chronic Mild Stress ◽  
Mild Stress ◽  
Stress Model ◽  
Unpredictable Chronic Mild Stress
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