Pineal germinoma with widespread extracranial metastases

1985 ◽  
Vol 1 (2) ◽  
pp. 118-122 ◽  
Author(s):  
Kitai Kim ◽  
Bon Chul Koo ◽  
Richard R. Delaflor ◽  
Bahu S. Shaikh
Keyword(s):  
Pineal Germinoma ◽  
Extracranial Metastases

Pineal Germinoma with Extracranial Metastases: Case Report

2004 ◽  
Vol 51 (2) ◽  
pp. 191
Author(s):  
Young Rang Lee ◽  
Seung Ro Lee ◽  
Dong Woo Park ◽  
Chang Kok Hahm ◽  
Moon Hyang Park ◽  
...  
Keyword(s):  
Case Report ◽  
Pineal Germinoma ◽  
Extracranial Metastases

MR Imaging Findings of Pineal Germinoma: Focus on Differential Diagnosis from Other Germ Cell Tumors

1998 ◽  
Vol 39 (4) ◽  
pp. 639
Author(s):  
Hyun Jin Kim ◽  
Ho Kyu Lee ◽  
Jae Kyun Kim ◽  
Ji Hoon Shin ◽  
Choong Gon Choi ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Mr Imaging ◽  
Germ Cell ◽  
Germ Cell Tumors ◽  
Imaging Findings ◽  
Pineal Germinoma

scholarly journals Extracranial metastases in secondary glioblastoma multiforme: a case report

BMC Neurology ◽  
2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Jessica Rossi ◽  
Lucia Giaccherini ◽  
Francesco Cavallieri ◽  
Manuela Napoli ◽  
Claudio Moratti ◽  
...  
Keyword(s):  
Brain Lesion ◽  
Rare Event ◽  
Subsequent Development ◽  
World Health ◽  
Who Grade ◽  
Systemic Involvement ◽  
Grade Ii ◽  
The Stability ◽  
Health Organization ◽  
Extracranial Metastases

Abstract Background Glioblastoma (GBM) is known for its devastating intracranial infiltration and its unfavorable prognosis, while extracranial involvement is a very rare event, more commonly attributed to IDH wild-type (primary) GBM evolution. Case presentation We present a case of a young woman with a World Health Organization (WHO) grade II Astrocytoma evolved to WHO grade IV IDH mutant glioblastoma, with subsequent development of lymphatic and bone metastases, despite the favorable biomolecular pattern and the stability of the primary brain lesion. Conclusions Our case highlights that grade II Astrocytoma may evolve to a GBM and rarely lead to a secondary metastatic diffusion, which can progress quite rapidly; any symptoms referable to a possible systemic involvement should be carefully investigated.

Unusual clinical presentation of a presumed pineal germinoma with two disseminated lesions

Neurosurgery ◽  
1988 ◽  
Vol 23 (2) ◽  
pp. 235???6
Author(s):  
S Nakano ◽  
H Uehara ◽  
K Kinoshita
Keyword(s):  
Clinical Presentation ◽  
Pineal Germinoma

Solitary Fibrous Tumors in the Central Nervous System

2003 ◽  
Vol 127 (4) ◽  
pp. 432-439 ◽  
Author(s):  
Tarik Tihan ◽  
Michael Viglione ◽  
Marc K. Rosenblum ◽  
Alessandro Olivi ◽  
Peter C. Burger
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Biological Behavior ◽  
Clinicopathologic Features ◽  
Distinct Entity ◽  
Total Resection ◽  
Solitary Fibrous Tumors ◽  
The Central Nervous System ◽  
Extracranial Metastases

Abstract Context.—Solitary fibrous tumors (SFTs) of the central nervous system are rare neoplasms that usually present as dura-based masses and clinically resemble meningiomas. Histologically, they can be similar to fibrous meningioma or hemangiopericytoma (HPC). In particular, densely cellular regions seen in some SFTs can be indistinguishable from HPC. Little is known about the biological behavior of SFTs, although most seem amenable to total resection. Objectives.—To define the clinicopathologic spectrum of SFTs in the central nervous system and to outline their differences from HPC and meningioma. Design.—We present the clinicopathologic features of 18 patients with SFT and compare them with those of an age- and sex-matched cohort of HPCs. Results.—Eleven SFTs were supratentorial, 3 were infratentorial, and 4 were intraspinal. Four of the 18 tumors were intra-axial (2 in the lateral ventricles and 2 within the spinal cord). Histologically, SFTs were similar to their soft tissue counterparts. Six tumors (6/18) had densely cellular regions, and 1 tumor showed frankly anaplastic features. All but 3 patients underwent gross total resection, and there were no metastases or tumor-related mortalities during the median follow-up of 40 months. In contrast, there were 15 local recurrences (83%), 5 extracranial metastases (27%), and 4 tumor-related deaths (22%) in the HPC cohort. Conclusions.—Our study presents the clinicopathologic features of SFT as a distinct entity from both meningioma and HPC. We also present unusual examples of anaplastic, intraventricular, and intramedullary spinal SFTs that expand the clinicopathologic spectrum of these uncommon and sometimes diagnostically difficult neoplasms.

scholarly journals Extensive systemic metastases from primary central nervous system haemangiopericytoma

2020 ◽  
Vol 6 (2) ◽  
pp. 20190081
Author(s):  
Chi Long Ho ◽  
Jeremy JH Lam ◽  
Robert Chun Chen
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Fatal Outcome ◽  
Imaging Features ◽  
Tumour Control ◽  
Local Tumour Control ◽  
Meningeal Tumour ◽  
Local Tumour ◽  
The Central Nervous System ◽  
Extracranial Metastases

Primary intracranial tumours rarely metastasise outside of the central nervous system (CNS). This report describes a rare case of recurrent meningeal haemangiopericytoma with extensive systemic metastases, which eventually resulted in a fatal outcome. We discuss some prevailing theories as to the rarity of extracranial metastases from primary CNS haemangiopericytoma, and elucidate the epidemiology, imaging features, differential diagnosis, treatment, and prognosis of this unusual but surprisingly aggressive meningeal tumour. Besides aggressive treatment for local tumour control, patients with primary CNS haemangiopericytoma require long-term post-treatment surveillance to detect systemic metastases.

Pineal germinoma: Diagnosis, treatment and tumor response

1987 ◽  
Vol 8 (3) ◽  
pp. 267-270 ◽  
Author(s):  
S. Ferla ◽  
S. Spartà ◽  
R. Giordano ◽  
P. L. Zorat ◽  
G. Marin ◽  
...  
Keyword(s):  
Tumor Response ◽  
Pineal Germinoma

scholarly journals Hearing Loss, Tinnitus and Pineal Germinoma: Parinaud Dorsal Midbrain Syndrome Revisited

Oncogen ◽  
2019 ◽  
Vol 2 (1) ◽  
Author(s):  
Rithvik Marri ◽  
Harini Rao ◽  
Diana S Osorio ◽  
Jonathan L Finlay
Keyword(s):  
Hearing Loss ◽  
Midbrain Syndrome ◽  
Pineal Germinoma ◽  
Dorsal Midbrain Syndrome
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