Bile cytology diagnosis in challenging cases: Validation of diagnostic bile cytology criteria and extensive study for immunocytochemical markers

2022 ◽  
Author(s):  
Naoki Sano ◽  
Kenichi Tabata ◽  
Tomohiro Oda ◽  
Miki Yanagita ◽  
Tomoko Suzuki ◽  
...  
Keyword(s):  
Extensive Study ◽  
Bile Cytology

Examination of Schistosome Cercariae and Schistosomules by Scanning Electron Microscopy

1969 ◽  
Vol 27 ◽  
pp. 50-51
Author(s):  
D. Johnson ◽  
P. Moriearty
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
High Resolution ◽  
Light Microscopy ◽  
Surface Structure ◽  
Extensive Study ◽  
Scanning Microscopy ◽  
Host Parasite ◽  
Conventional Electron Microscopy ◽  
Scanning Electron

Since several species of Schistosoma, or blood fluke, parasitize man, these trematodes have been subjected to extensive study. Light microscopy and conventional electron microscopy have yielded much information about the morphology of the various stages; however, scanning electron microscopy has been little utilized for this purpose. As the figures demonstrate, scanning microscopy is particularly helpful in studying at high resolution characteristics of surface structure, which are important in determining host-parasite relationships.

Methods for making stereoslides and -prints, with freeze-etched olfactory epithelium as example

1984 ◽  
Vol 42 ◽  
pp. 704-705
Author(s):  
Bert Ph. M. Menco ◽  
Ido F. Menco ◽  
Frans L.T. Verdonk
Keyword(s):  
Electron Microscope ◽  
Olfactory Epithelium ◽  
Three Dimensional ◽  
Supporting Cell ◽  
Structural Features ◽  
Extensive Study ◽  
Sprague Dawley ◽  
Freezing Method ◽  
Respiratory Epithelia ◽  
Three Dimensional Presentation

Previously we presented an extensive study of the distributions of intramembranous particles of structures in apical surfaces of nasal olfactory and respiratory epithelia of the Sprague-Dawley rat. For the same structures these distributions were compared in samples which were i) chemically fixed and cryo-protected with glycerol before cryo-fixation, after excision, and ii)ultra-rapidly frozen by means of the slam-freezing method. Since a three-dimensional presentation markedly improves visualization of structural features micrographs were presented as stereopairs. Two exposures were made by tiling the sample stage of the electron microscope 6° in either direction with an eucentric goniometer. The negatives (Agfa Pan 25 Professional) were reversed with Kodak Technical Pan Film 2415 developed in D76 1:1. The prints were made from these reversed negatives. As an example tight-junctional features of an olfactory supporting cell in a region where this cell conjoined with two other cells are presented (Fig. 1).

Arg506GIn Factor V Mutation (Factor V Leiden) in Patients with Ischaemic Cerebrovascular Disease and Survivors of Myocardial Infarction

1995 ◽  
Vol 73 (04) ◽  
pp. 558-560 ◽  
Author(s):  
Kimmo Kontula ◽  
Antti Ylikorkala ◽  
Helena Miettinen ◽  
Alpo Vuorio ◽  
Ritva Kauppinen-Mäkelin ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Cerebrovascular Disease ◽  
Factor V Leiden ◽  
Mutant Gene ◽  
Arterial Disease ◽  
Cerebrovascular Diseases ◽  
Extensive Study ◽  
Carrier Status ◽  
Factor V ◽  
Ischaemic Attack

SummaryThe point mutation Arg506->Gln of factor V was recently shown to be an important and relatively common genetic cause of venous thromboembolism. Using a DNA technique based on polymerase chain reaction, we surveyed the blood samples of 236 patients with ischaemic stroke or a transient ischaemic attack, 122 survivors of myocardial infarction and 137 control subjects for the presence of this mutation. Although the frequency of the factor V mutation in patients with arterial disease (4.5%) was not significantly different from that in healthy blood donors (2.9%), a carrier status for this mutant gene was associated with symptoms of migraine and relatively mild angiographic abnormalities among patients with cerebrovascular disease. A more extensive study addressing the occurrence and significance of the mutant factor V mutation in patients with vasospastic cerebrovascular diseases seems to be warranted.

On the Margins of Modernism

2017 ◽  
Author(s):  
Christopher Rosenmeier
Keyword(s):  
Short Stories ◽  
Detailed Analysis ◽  
Chinese Literature ◽  
Popular Literature ◽  
Extensive Study ◽  
Wide Range ◽  
Chinese Fiction ◽  
Scant Attention ◽  
Narrative Techniques ◽  
Chinese Writing

Xu Xu and Wumingshi were among the most widely read authors in China during and after the Second Sino-Japanese War (1937–1945). Despite being an integral part of the Chinese literary scene, their bestselling fiction has, however, been given scant attention in histories of Chinese writing. This book is the first extensive study of Xu Xu and Wumingshi in English or any other Western language and it re-establishes their importance within the popular Chinese literature of the 1940s. Their romantic novels and short stories were often set abroad and featured a wide range of stereotypes, from pirates, spies and patriotic soldiers to ghosts, spirits and exotic women who confounded the mostly cosmopolitan male protagonists. Christopher Rosenmeier’s detailed analysis of these popular novels and short stories shows that such romances broke new ground by incorporating and adapting narrative techniques and themes from the Shanghai modernist writers of the 1930s, notably Shi Zhecun and Mu Shiying. The study thereby contests the view that modernism had little lasting impact on Chinese fiction, and it demonstrates that the popular literature of the 1940s was more innovative than usually imagined, with authors, such as those studied here, successfully crossing the boundaries between the popular and the elite, as well as between romanticism and modernism, in their bestselling works.

British Women Amateur Filmmakers

2018 ◽  
Author(s):  
Annamaria Motrescu-Mayes ◽  
Heather Norris Nicholson
Keyword(s):  
Postcolonial Studies ◽  
Extensive Study ◽  
Aesthetic Judgment ◽  
Visual Anthropology ◽  
Gender History ◽  
Remote Communities ◽  
Visual Narratives ◽  
And Gender ◽  
British Commonwealth ◽  
Film Making

In the rapidly growing study of amateur film, this groundbreaking book addresses the development of British women's amateur visual practice. Drawing upon social and visual anthropology, imperial and postcolonial studies and British, Commonwealth and gender history, the authors explore how women in Britain and overseas, used the evolving technologies of moving imagery to create visual stories about their lives and times. Locating the making, watching and sharing of women's recreational film-making against wider societal, technological and ideological changes, British Women Amateur Filmmakers discloses how women from varied backgrounds negotiated changing lifestyles, attitudes and opportunities as they created first personal visual narratives about themselves and the world around them. Using non-fictional films and animations, the authors invite readers to view films through different interpretative lens and provide detailed contexts for their case-studies and survey of over forty women amateur filmmakers. Whether in remote communities, suburban homes, castles, missionary or diplomatic enclaves, or simply travelling as intrepid sightseers, women filmed their companions, other people and their surroundings, not only as observers but often displaying agency, autonomy and aesthetic judgment during decades when careers, particularly after marriage, were often denied in film and other professions. Research across Britain on films in private hands and specialist archives, interviews and extensive study of the Institute of Amateur Cinematographers (IAC's) collections enable the authors to reposition an activity once thought of as overwhelmingly male and middle class.

A Critical Study of Stephen King and Horror Fiction

2019 ◽  
Vol 7 (5) ◽  
pp. 23
Author(s):  
Dr. Sudhir V. Nikam ◽  
Mr. Rajkiran J. Biraje
Keyword(s):  
Research Problem ◽  
Extensive Study ◽  
Serial Killers ◽  
Critical Study ◽  
Research Attention ◽  
Stephen King ◽  
Special Place ◽  
Fiction Writers ◽  
Horror Fiction ◽  
A Site

This present research undertakes the extensive study of horror fiction genre with reference to the select novels of one of the finest and celebrated horror fiction writers of all time, Stephen King. This paper is a substantial assessment of the select horror fiction of King. The research problem revolves extensively around the word fear. Stephen King has conjured up the images of most horrific creatures, monsters, places, and stories, and some of the most enduring villains in fiction. These unimaginable evil beings test the limits of the protagonist. Some of these villains have gone to the extent of becoming as famous (or infamous) as the writer himself. Many of Stephen King villains are monsters of the human variety such as serial killers, power hungry despots, nihilists, etc. His most memorable and monumental characters are the supernatural ones who use their dark powers to twist the orderly world around them into a special place of chaos and pain. It has been assumed that the horror elements in the fiction of Stephen King are the result of his strategic use of supernaturalist and non-supernaturalist elements. The techniques that he uses to evoke horror in reader have been treated as a site for research attention by the researcher.

THE NATIONAL EMPLOYMENT PLAN IN BULGARIA - ANALYSIS AND OPPORTUNITIES FOR CHANGE

2017 ◽  
Author(s):  
Venelin Krastev Terziev ◽  
◽  
Ivan Stefanov Ivanov ◽  
Keyword(s):  
Labour Market ◽  
Emergency Situation ◽  
Extensive Study ◽  
Financial Resource ◽  
The State

This paper is the part of an extensive study which analyzes and examines the processes on the Bulgarian market that unfold in the emergency situation resulting from the COVID-19 pandemics. The focus is on the state of the labour market before the pandemic crisis and the subsequent changes in the current national employment plan in view of the challenges of the situation caused by COVID-19. It proposes measures and supports actions for restructuring the financial resource for adaptation of the plan to the new challenge to the labour market in Bulgaria.

W-Peakedness: A Simulation based Study

2015 ◽  
Vol 1 (1) ◽  
Author(s):  
Suboohi Safdar ◽  
Dr. Ejaz Ahmed
Keyword(s):  
Probability Distributions ◽  
Extensive Study ◽  
Descriptive Statistics ◽  
Target Point ◽  
Density Functions ◽  
Central Value ◽  
Distribution Shape ◽  
Simulation Based ◽  
Different Shapes ◽  
Kurtosis Coefficient

Kurtosis is a commonly used descriptive statistics. Kurtosis “Coefficient of excess” is critically reviewed in different aspects and is called as, measuring the fatness of the tails of the density functions, concentration towards the central value, scattering away from the target point or degree of peakedness of probability distribution. Kurtosis is referred to the shape of the distribution but many distributions having same kurtosis value may have different shapes while Kurtosis may exist when peak of a distribution is not in existence. Through extensive study of kurtosis on several distributions, Wu (2002) introduced a new measure called “W-Peakedness” that offers a fine capture of distribution shape to provide an intuitive measure of peakedness of the distribution which is inversely proportional to the standard deviation of the distribution. In this paper the work is extended for different others continuous probability distributions. Empirical results through simulation illustrate the proposed method to evaluate kurtosis by W-peakedness

On the limits of active module identification

2021 ◽  
Author(s):  
Olga Lazareva ◽  
Jan Baumbach ◽  
Markus List ◽  
David B Blumenthal
Keyword(s):  
Gene Expression ◽  
Gene Expression Data ◽  
Small Diameter ◽  
Extensive Study ◽  
Biological Knowledge ◽  
Expression Data ◽  
Module Identification ◽  
Ppi Networks ◽  
Novel Algorithms ◽  
Context Specific

Abstract In network and systems medicine, active module identification methods (AMIMs) are widely used for discovering candidate molecular disease mechanisms. To this end, AMIMs combine network analysis algorithms with molecular profiling data, most commonly, by projecting gene expression data onto generic protein–protein interaction (PPI) networks. Although active module identification has led to various novel insights into complex diseases, there is increasing awareness in the field that the combination of gene expression data and PPI network is problematic because up-to-date PPI networks have a very small diameter and are subject to both technical and literature bias. In this paper, we report the results of an extensive study where we analyzed for the first time whether widely used AMIMs really benefit from using PPI networks. Our results clearly show that, except for the recently proposed AMIM DOMINO, the tested AMIMs do not produce biologically more meaningful candidate disease modules on widely used PPI networks than on random networks with the same node degrees. AMIMs hence mainly learn from the node degrees and mostly fail to exploit the biological knowledge encoded in the edges of the PPI networks. This has far-reaching consequences for the field of active module identification. In particular, we suggest that novel algorithms are needed which overcome the degree bias of most existing AMIMs and/or work with customized, context-specific networks instead of generic PPI networks.

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