Cytologic analysis of vitreous fluids: A retrospective review of our 24 years of experience

2021 ◽  
Author(s):  
Gabriel L. Collins ◽  
Elizabeth W. Hubbard ◽  
Christopher T. Clark ◽  
Lisa D. Duncan ◽  
Laurentia Nodit
Keyword(s):  
Retrospective Review ◽  
Years Of Experience ◽  
Cytologic Analysis

Vertebral osteomyelitis: Retrospective review of 11 years of experience

2014 ◽  
Vol 46 (3) ◽  
pp. 193-199 ◽  
Author(s):  
Sharon Weissman ◽  
R. David Parker ◽  
Wajid Siddiqui ◽  
Shana Dykema ◽  
Joseph Horvath
Keyword(s):  
Retrospective Review ◽  
Vertebral Osteomyelitis ◽  
Years Of Experience

scholarly journals Primary Intra-Arterial Chemotherapy for Retinoblastoma in the Intravitreal Chemotherapy Era: Five Years of Experience

2018 ◽  
Vol 5 (2) ◽  
pp. 139-146 ◽  
Author(s):  
Lauren A. Dalvin ◽  
Mamta Kumari ◽  
Vera Adobea Essuman ◽  
Shormin Shohelly Shipa ◽  
David  Ancona-Lezama ◽  
...  
Keyword(s):  
Adjuvant Therapy ◽  
Retrospective Review ◽  
Tumor Control ◽  
Primary Therapy ◽  
Years Of Experience ◽  
Intravitreal Chemotherapy ◽  
Group B ◽  
Group D ◽  
Unilateral Group ◽  
Vitreous Seeds

Purpose: To report our 5-year experience with intra-arterial chemotherapy (IAC) in the intravitreal chemotherapy (IvitC) era. Methods: Retrospective review of retinoblastoma treated with primary unilateral IAC in the IvitC era (2012–2017). Results: There were 34 eyes treated with IAC alone versus 20 eyes treated with IAC plus IvitC for vitreous seeds. IAC (IAC alone vs. IAC plus IvitC) consisted of melphalan (41 vs. 10%) or melphalan plus topotecan (59 vs. 90%, p = 0.03). IvitC consisted of melphalan (60%) or melphalan plus topotecan (40%). Tumor control and globe salvage were achieved in 100% of group B and C eyes without IvitC. Despite more extensive vitreous seeds in the IvitC group (p < 0.01), comparison of IAC alone versus IAC plus IvitC revealed no difference in tumor control for group D (88 vs. 69%, p = 0.36) or group E (67 vs. 100%, p = 0.25) and no difference in globe salvage for group D (88 vs. 69%, p = 0.36) or group E (58 vs. 57%, p = 0.39). Conclusions: IAC is effective as primary therapy for unilateral group B, C, D, and E retinoblastoma. IvitC is an important adjuvant therapy to achieve comparable globe salvage rates for group D and E eyes with persistent active vitreous seeds.

The impact of reporting tumor size in breast core needle biopsies on tumor stage: A retrospective review of five years of experience at a single institution

2019 ◽  
Vol 38 ◽  
pp. 26-28
Author(s):  
Sarah Alghamdi ◽  
Sabrina Oneto ◽  
Anthony Tuzzolo ◽  
Odille Mejia ◽  
Christopher A. Febres-Aldana ◽  
...  
Keyword(s):  
Retrospective Review ◽  
Tumor Size ◽  
Tumor Stage ◽  
Years Of Experience ◽  
Single Institution ◽  
Core Needle ◽  
The Impact

Improving the diagnostic yield of biliary stricture biopsies using a directional atherectomy device.

2021 ◽  
Vol 39 (15_suppl) ◽  
pp. e16167-e16167
Author(s):  
Glynn Weldon Gilcrease ◽  
Preston Eiswirth ◽  
Hannah Beth Suchy ◽  
Benjamin L Witt ◽  
Rulon L Hardman ◽  
...  
Keyword(s):  
Retrospective Review ◽  
Diagnostic Yield ◽  
High Sensitivity ◽  
Years Of Experience ◽  
Predictive Values ◽  
Evaluation Score ◽  
Institutional Review ◽  
Directional Atherectomy ◽  
Biliary Biopsy ◽  
Similar Accuracy

e16167 Background: Diagnosing the pathologic etiology of biliary strictures presents challenges that have been well-documented. Accuracy of traditional brushing and fine needle aspirate techniques range from 44% to 73%.2 Over the last 2 decades the use of atherectomy catheter biliary biopsy has demonstrated high sensitivity and positive predictive values with a low complication rate. This endoluminal approach allows for larger volume histologic samples, allowing for the potential to obtain adequate tissue for next generation sequencing (NGS). The aim of this retrospective review of a single-center’s experience was to define the accuracy, ease of evaluation, and the ability to obtain NGS for personalized treatment. Methods: A retrospective review was performed under a waiver from the Institutional Review Board. A search of medical records from 1/2016 to 2/2021 yielded 20 biopsies in 19 patients. The 20 biopsies were completed by 4 interventional radiologists with between 2-11 years of experience. All available samples were analysed by a pathologist with greater than 10 years of experience and graded for adequacy and feasibility of NGS. Results: The patient population was 53% female with average age of 65.1 years. 12/19 (63%) patients had prior non-atherectomy biopsy attempts. The average ease of evaluation score for the 19 biopsies was 7.8/9, compared to 6.2/9 for the brushing specimens obtained from a subset of the same patients. Seven biopsies were positive for malignancy, ten were benign and three were non-diagnostic. The 7 biopsies that rendered a definitive diagnosis of malignancy had an average ease of evaluation score 8.7/9. The overall accuracy rate was 78.9%, and 71% of malignant samples were deemed adequate for NGS. There were two biopsy related complications; one pseudoaneurysm treated with embolization and one biliary drain dislodgement. Conclusions: Biliary biopsy using an atherectomy device has similar accuracy to traditional techniques; however, it allows for improved diagnostic yield and increased tissue specimen with 71% of samples adequate for NGS testing.

Sign in / Sign up

Export Citation Format

Share Document