Metastatic breast carcinoma presenting in the uterine cervix: Lessons learned from liquid‐based Pap test

2020 ◽  
Author(s):  
Yan Shi ◽  
Melissa Yee‐Chang ◽  
Wei Sun ◽  
Aylin Simsir
2021 ◽  
Vol 8 (2) ◽  
pp. C32-34
Author(s):  
Maymol P Varghese ◽  
Sreeja Raju ◽  
Savithri MC ◽  
Joy Augustine ◽  
Mathew Varghese

Uterine cervix involvement as a site of metastasis from a distant primary tumor is rare. Metastasis from breast carcinoma in a patient undergoing treatment is even rarer.  The present case report is of a 47-year-old lady with history of carcinoma breast on treatment and who was referred to our hospital with complaints of lower limb oedema, low backache and postmenopausal whitish discharge per vaginum. Per vaginal examination revealed a lesion arising in the cervix extending up to the anterior vaginal wall suggestive of a clinical diagnosis of carcinoma cervix. Subsequent biopsy from the lesion showed malignant cells arranged in Indian file pattern and focal alveolar pattern, hinting at a diagnosis of Invasive lobular carcinoma metastasis.  The neoplasm was positive for ER, PR and GATA-3 and negative for Her2/neu and E-cadherin confirming our diagnosis. Although rare, the poor outcome in such patients makes it even more important for its identification and the need for them to undergo careful routine gynecologic examination.


2010 ◽  
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pp. 681-685 ◽  
Author(s):  
Franco Fulciniti ◽  
Luciano Pezzullo ◽  
Maria Grazia Chiofalo ◽  
Daniela Butera ◽  
Nunzia Simona Losito ◽  
...  

Cancer ◽  
2004 ◽  
Vol 101 (7) ◽  
pp. 1524-1528 ◽  
Author(s):  
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Vasilis Karavasilis ◽  
Lida Kostadima ◽  
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...  

Cancer ◽  
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pp. 1150-1157 ◽  
Author(s):  
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Laura Esparza-Guerra ◽  
Hwee-Yong Yap ◽  
Giuseppe Fraschini ◽  
Gerald Bodey ◽  
...  

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