Imprint cytology of clear cell sarcoma-like tumor of the gastrointestinal tract in the small intestine: A case report

2017 ◽  
Vol 45 (12) ◽  
pp. 1137-1141 ◽  
Author(s):  
Takashi Kato ◽  
Shin Ichihara ◽  
Hiroko Gotoda ◽  
Shunji Muraoka ◽  
Terufumi Kubo ◽  
...  
Keyword(s):  
Small Intestine ◽  
Case Report ◽  
Gastrointestinal Tract ◽  
Clear Cell ◽  
Clear Cell Sarcoma ◽  
Imprint Cytology ◽  
Cell Sarcoma

scholarly journals A long-term survivor of clear cell sarcoma-like tumor of the gastrointestinal tract with liver metastasis: a case report

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Takuhisa Okada ◽  
Yasumitsu Hirano ◽  
Shintaro Ishikawa ◽  
Hiroka Kondo ◽  
Toshimasa Ishii ◽  
...  
Keyword(s):  
Small Intestine ◽  
Lymph Node ◽  
Gastrointestinal Tract ◽  
Liver Metastasis ◽  
Surgical Resection ◽  
Clear Cell ◽  
Clear Cell Sarcoma ◽  
Cell Sarcoma

Abstract Background Clear cell sarcoma-like tumor of the gastrointestinal tract (CCSLTGT) is extremely rare. It is a mesenchymal neoplasm that usually forms in the small intestine of adolescents and young adults, is prone to local recurrence and metastasis, and has a high mortality rate. We report a patient with CCSLTGT with lymph node- and liver metastases, who continues to survive 6 years after initial surgical resection. Case presentation A 38-year-old woman presented with lightheadedness. Laboratory analysis revealed anemia (hemoglobin, 6.7 g/dL), and enhanced computed tomography (CT) demonstrated a mass in the small intestine, about 6 cm in diameter, with swelling of 2 regional lymph nodes. Double-balloon small intestine endoscopic examination revealed a tumor accompanied by an ulcer; the biopsy findings suggested a primary cancer of the small intestine. She was admitted, and we then performed a laparotomy for partial resection of the small intestine with lymph node dissection. Pathologic examination revealed CCSLTGT with regional lymph node metastases. About 3 years later, follow-up CT revealed a single liver metastasis. Consequently, she underwent a laparoscopic partial liver resection. Histopathologic examination confirmed that the liver metastasis was consistent with CCSLTGT. It has now been 3 years without a recurrence. Conclusion Repeated radical surgical resection with close follow-up may be the only way to achieve long-term survival in patients with CCLSTGT.

Malignant Gastrointestinal Neuroectodermal Tumor: a case report and a review of the literature

2021 ◽  
Vol 156 (Supplement_1) ◽  
pp. S66-S67
Author(s):  
B Youssef ◽  
D Asberry ◽  
R Mohamed
Keyword(s):  
Case Report ◽  
Gastrointestinal Tract ◽  
Clear Cell ◽  
Muscularis Propria ◽  
Clear Cell Sarcoma ◽  
Neuroectodermal Tumor ◽  
High Rate ◽  
Cell Sarcoma ◽  
Molecular Features ◽  
Eosinophilic Cytoplasm

Abstract Introduction/Objective Malignant gastrointestinal neuroectodermal tumor (GNET) is a rare soft tissue tumor arising in the wall of the gastrointestinal tract. The GNET was first described as an osteoclast rich tumor of the gastrointestinal tract with features resembling clear cell sarcoma, with only few cases reported in the literature. Methods/Case Report We report a case of a 71-year-old man with a past medical history of hypertension, hyperlipidemia, and benign prostatic hyperplasia presented with complaints of dyspnea, dizziness, fatigue, black stools, and a recent syncopal episode. Laboratory testing revealed anemia (HB 5.4 g/dL). Esophagogastroduodenoscopy demonstrated a submucosal gastric mass. An abdominal CT scan confirmed a 7.8 cm mass along the gastric cardia and fundus. Results (if a Case Study enter NA) Biopsy rendered a gastrointestinal neuroectodermal tumor (GNET). Microscopically, the tumor cells were spindle with eosinophilic cytoplasm and arranged in fascicules. They were positive for CD56, CD99, and Fli-1, synaptophysin, and negative for chromogranin, TTF-1, SMA, desmin, CD34, EMA, pan-cytokeratin, and lymphoid markers. Two months later, further imaging confirmed metastasis to the liver and spleen. GNETs typically arise within the muscularis propria of the gastrointestinal tract and often extend into the submucosa and subserosa. Conclusion The most important differential of GNET is the clear cell sarcoma of the gastrointestinal tract (CCS-GI). Both share similar morphological as well as molecular features and show S100 positivity; however, the lack of melanocytic differentiation in GNET distinguishes it from CCS-GI. Both typically show rearrangements of the EWSR1 gene, with t(12;22) (q13;q12) EWSR1-ATF1 or t(2;22)(q34;q12) EWSR1-CREB1 fusions. Pathologists should be aware of GNET diagnostic entity due to its aggressive behavior and high rate of recurrence and mortality even after complete resection.

Clear cell sarcoma of the gastrointestinal tract after very low-dose therapeutic radiation therapy: a case report

2012 ◽  
Vol 47 (10) ◽  
pp. 1943-1945 ◽  
Author(s):  
Joanna C. Yang ◽  
Alexander J. Chou ◽  
Kevin C. Oeffinger ◽  
Michael P. La Quaglia ◽  
Suzanne L. Wolden
Keyword(s):  
Radiation Therapy ◽  
Case Report ◽  
Gastrointestinal Tract ◽  
Low Dose ◽  
Clear Cell ◽  
Clear Cell Sarcoma ◽  
Cell Sarcoma ◽  
Therapeutic Radiation

Malignant Melanoma of Soft Parts (Clear Cell Sarcoma): A Case Report

2003 ◽  
Vol 30 (7) ◽  
pp. 550-555 ◽  
Author(s):  
Takuya Seike ◽  
Kazuya Matsumoto ◽  
Hideki Nakanishi ◽  
Ichiro Hashimoto ◽  
Yoshiaki Kubo ◽  
...  
Keyword(s):  
Case Report ◽  
Malignant Melanoma ◽  
Clear Cell ◽  
Clear Cell Sarcoma ◽  
Cell Sarcoma

scholarly journals Clear cell sarcoma of the right lumbar region: A case report and review of the literature

2014 ◽  
Vol 8 (4) ◽  
pp. 1625-1627
Author(s):  
XUE-LI YANG ◽  
SAN-JUN LU ◽  
JIE XUE ◽  
YAN-FEN WU ◽  
JUN-LING SHI
Keyword(s):  
Case Report ◽  
Clear Cell ◽  
Clear Cell Sarcoma ◽  
Lumbar Region ◽  
Review Of The Literature ◽  
Cell Sarcoma ◽  
The Right

scholarly journals Phalangeal and Metacarpal Metastases from Clear Cell Sarcoma of the Kidney: A Case Report

1998 ◽  
Vol 39 (6) ◽  
pp. 1233
Author(s):  
Chan Kyo Kim ◽  
Joong Mo Ahn ◽  
Eung Yeop Kim ◽  
Hye Kyung Yoon ◽  
Bokyung Kim Han ◽  
...  
Keyword(s):  
Case Report ◽  
Clear Cell ◽  
Clear Cell Sarcoma ◽  
Cell Sarcoma

A Case Report of Clear Cell Sarcoma in Thigh

1982 ◽  
Vol 17 (1) ◽  
pp. 158
Author(s):  
Yung Khee Chung ◽  
Won Chang Park ◽  
Ik Yull Chang ◽  
Chang Rock Oh
Keyword(s):  
Case Report ◽  
Clear Cell ◽  
Clear Cell Sarcoma ◽  
Cell Sarcoma

scholarly journals Clear cell sarcoma of the kidney: a case report

1989 ◽  
Vol 4 (3) ◽  
pp. 149
Author(s):  
Joong Seok Seo ◽  
Yong Wook Park ◽  
Kye Yong Song ◽  
Seon Taek Chang
Keyword(s):  
Case Report ◽  
Clear Cell ◽  
Clear Cell Sarcoma ◽  
Cell Sarcoma
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