Smear cytology findings of large cell neuroendocrine carcinoma of the uterine cervix

2011 ◽  
Vol 41 (7) ◽  
pp. 636-639 ◽  
Author(s):  
Naoto Kuroda ◽  
Yukari Wada ◽  
Kaori Inoue ◽  
Masahiko Ohara ◽  
Keiko Mizuno ◽  
...  
2003 ◽  
Vol 22 (3) ◽  
pp. 226-230 ◽  
Author(s):  
Yuichiro Sato ◽  
Tomihiro Shimamoto ◽  
Satoshi Amada ◽  
Yujiro Asada ◽  
Tohru Hayashi

2018 ◽  
Vol 2018 ◽  
pp. 1-4
Author(s):  
Neema Hooker ◽  
Sveta Mohanan ◽  
R. Tucker Burks

Neuroendocrine tumors (NETs) are aggressive diseases developing from neuroendocrine cells that most frequently involve the gastro-entero-pancreatic tract and the lung, but more rarely are found in almost all body tissues. Limited biological and clinical data are currently available for NETs in uncommon sites, such as female genital tract. NETs represent 0.9% to 1.5% of the tumors of the uterine cervix. This case is reported on a 75-year-old Caucasian woman, presenting with dental and generalized pain for two weeks. Later during her admission, facial droop and diplopia were noticed. Radiological findings ruled out cerebrovascular accident but revealed multiple bone marrow lesions involving the left and the right clivus, right Meckel's cave, and posterior margin of the right cavernous sinus. Findings also included pulmonary nodules and adenopathy supporting diagnosis of likely stage IV metastatic carcinoma. Further imaging revealed homogeneous enhancement of the uterus suggestive of diffusely infiltrative carcinoma; pathology results confirmed large cell neuroendocrine carcinoma of the uterine cervix (LCNEC) giving her a 1.5-month median survival range.


2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Ryusuke Murakami ◽  
Iemasa Kou ◽  
Kenjiro Date ◽  
Hirofumi Nakayama

Large cell neuroendocrine carcinoma (LCNEC) of the uterine cervix is very rare and aggressive. The prognosis is very poor despite multimodal treatment. We report a virgin woman with FIGO stage 4b LCNEC of uterine cervix coexisting with squamous cell carcinoma. An early thirties virgin woman presented with 2-month history of abdominal pain. A chest X-ray showed multiple lung metastatic tumors. A vaginal smear showed malignant cells, and a biopsy specimen had features of LCNEC. The tumor showed trabecular patterns. Tumor cells possessed a moderate amount of cytoplasm, prominent nucleoli, and large nuclei. The tumor cells are stained positive for synaptophysin, chromogranin A, and neuron specific enolase (NSE). The invasive tumor cells in connection with cervical squamous epithelium were focally positive for 34bE12. We made a diagnosis of composite LCNEC and nonkeratinizing squamous cell carcinoma. High-risk HPV test was negative with hybridized captured method 2.


2007 ◽  
Vol 33 (2) ◽  
pp. 218-224 ◽  
Author(s):  
Siriwan Tangjitgamol ◽  
Sumonmal Manusirivithaya ◽  
Nantana Choomchuay ◽  
Surawute Leelahakorn ◽  
Thaowalai Thawaramara ◽  
...  

2003 ◽  
Vol 270 (3) ◽  
pp. 185-188 ◽  
Author(s):  
Yilmaz Dikmen ◽  
Mert Kazandi ◽  
Osman Zekioglu ◽  
Aydin Ozsaran ◽  
Mustafa Cosan Terek ◽  
...  

2018 ◽  
Vol 47 (2) ◽  
pp. 137-141
Author(s):  
Busra Ersan Erdem ◽  
Vural Çiğdem ◽  
Gezer Şener ◽  
Muezzinoglu Bahar ◽  
Yıldız Demir Kursat ◽  
...  

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