Diagnostic value of liquid-based (Liqui-PREP) preparations and interobserver reproducibility in fine needle aspiration cytology of the nodular thyroid lesions

2011 ◽  
Vol 40 (5) ◽  
pp. 388-393 ◽  
Author(s):  
U. S. Tetikkurt ◽  
F. Oz Puyan ◽  
F. Oz ◽  
N. Erdogan ◽  
S. Ceylan ◽  
...  
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Diagnostic Value ◽  
Needle Aspiration ◽  
Interobserver Reproducibility ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology ◽  
Thyroid Lesions

Cytopathological Evaluation of Thyroid Lesions Based on Bethesda System in Patients Attending Birat Medical College and Teaching Hospital

2020 ◽  
Vol 22 (4) ◽  
pp. 260-265
Author(s):  
Neeta Kafle ◽  
B Koirala ◽  
SU Kafle ◽  
M Singh ◽  
A Sinha
Keyword(s):  
Teaching Hospital ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Medical College ◽  
Bethesda System ◽  
Needle Aspiration Cytology ◽  
Thyroid Lesions

More than 50% of the world’s population has at least a thyroid nodule. Detail clinical examination and radiology may help in diagnosing thyroid lesions but the management depends upon the cytopathological diagnosis. Optimum use of fine needle aspiration cytology (FNAC) and better understanding of cytomorphological characteristic of thyroid lesions by using Bethesda system, triaging of patients who are to be treated medically or surgically is more accurate. The objective of this present study is cytopathological evaluation of thyroid lesions based on Bethesda System in patients attending Birat Medical College and Teaching Hospital. The objective was also to correlate the cytological findings with histopathological findings where ever possible. A total of 104 patients with thyroid lesions underwent fine needle aspiration cytology in a period of a year (September 1, 2019 to August 31, 2020). Cytological features were evaluated and classified according to the Bethesda system. Histopathological features were evaluated and correlated wherever available. Among 104 patients with thyroid lesions 93 were female and 11 were male. Four cases turned out to be non diagnostic, 85 benign, three Atypia of undetermined significance, three Suspicious for follicular neoplasm and eight Suspicious of malignancy and one Malignant according to Bethesda system. Histopathology specimen was received in 31 patients out of whom 20 (64.5%) patients were reported as colloid nodule, two follicular adenoma, one Hurthle cell adenoma, six papillary carcinoma and two follicular carcinoma. Medullary carcinoma and anaplastic carcinoma were not seen in the patients evaluated. Specificity and sensitivity of fine needle aspiration cytology was 94.7% and 88.9% respectively. Thus reporting thyroid lesions FNAC with Bethesda system allow a more specific cytological diagnosis.

scholarly journals Cytopathological Evaluation of Thyroid by Fine Needle Aspiration Cytology and Correlation with T3 T4 and TSH Levels

2015 ◽  
Vol 3 (4) ◽  
pp. 37-41
Author(s):  
Suman Poudel ◽  
Sudeep Regmi ◽  
Anita Shahi ◽  
Ashok Samdurkar
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Thyroid Function Test ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Asymptomatic Patients ◽  
Significant Difference ◽  
Needle Aspiration Cytology ◽  
Thyroid Lesions

INTRODUCTION: Fine Needle Aspiration Cytology (FNAC) of the thyroid gland is now a well-established, first line diagnostic test for the evaluation of thyroid lesions. An FNA is performed along with Thyroid Function Test (TFT) profile to correlate cytology with hormonal function in symptomatic or asymptomatic patients. MATERIALAND METHODS: Total of 117 cases of FNAC of thyroid lesions were selected who had undergone TFT profile. The lesions were evaluated cytologically and categorized according to Bethesda System of classification and correlated with TFT profile. RESULTS: Out of 117 cases studied, the middle aged (20-49 years) females were most commonly affected by thyroid diseases. The predominant lesions cytologically were Benign Follicular Nodule (BFN) with frequency of 51.3%.With respect to hormonal status most of the lesions were Euthyroid (53.8%). The study showed no significant difference in mean of TFT profile with regard to various FNAC diagnoses. CONCLUSION: The study showed that FNAC and TFT profile both are essential for the proper management of thyroid lesions and, there is no significant difference between FNAC diagnosis and mean TFT profile.

Correlation of Fine Needle Aspiration Cytology of Thyroid Gland with Histopathological Results

2018 ◽  
Vol 90 (5) ◽  
pp. 1-5 ◽  
Author(s):  
Ewa Machała ◽  
Jan Sopiński ◽  
Iulia Iavorska ◽  
Krzysztof Kołomecki
Keyword(s):  
Fine Needle Aspiration ◽  
Predictive Value ◽  
Fine Needle Aspiration Cytology ◽  
Cost Effective ◽  
Needle Aspiration ◽  
The Other ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology ◽  
Thyroid Lesions

ABSTRACT Fine needle aspiration cytology (FNAC) is considered as the gold standard diagnostic test for the diagnosis of thyroid nodules. It is a cost-effective procedure that provides specific diagnosis rapidly with minimal complications. It plays an important role in the determination of treatment- patients with suspected malignancy diagnosis can be subjected to surgery. On the other hand it can decrease the rate of unnecessary surgeries. Aims: The aim of this study was to evaluate and compare the correlation, accuracy of fine needle aspirational cytology (FNAC) in the diagnosis of thyroid lesions with the final histopathologic diagnosis in the surgical specimens. Materials and Methods: In our study we have performed a retrospective analysis of a case series of patients who were admitted to the Department of Endocrine, General and Oncological Surgery of Hospital of M. Kopernik in Łodź (Poland) between May 2016 and December 2017 and underwent FNAC with subsequent surgery. Cytological diagnosis was classified into six Bethesda categories. Results: On cytological examination 1070/1262 were reported as benign, 49 malignant and 143 suspicious. On histopathological examination, 956/1070 cases were confirmed as benign but there were 114 discordant cases. Among the other cases histopathology diagnosis of malignancy matched in 45/49 and 128/143 cases.The sensitivity and specificity were 60,28% and 98,05% respectively. False positive rate was 1.95% and false negative rate was 39.72%. The positive predictive value was 90.1% and negative predictive value was 89.35%. Accuracy of FNA in differentiating benign from malignant thyroid lesions was 89,46%. Conclusions: Fine needle aspiration cytology is a simple, cost-effective and popular procedure for the diagnosis of thyroid cancer. It is recommended as the first line investigation for the diagnosis of thyroid lessions.

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