Clue to fine-needle aspiration diagnosis of pleural pneumocystoma: Neovascularization and Langhans' giant cell reaction

2005 ◽  
Vol 33 (2) ◽  
pp. 97-99
Author(s):  
Ronaldo L. Zamuco ◽  
Grace C.H. Yang
2001 ◽  
Vol 125 (8) ◽  
pp. 1091-1094
Author(s):  
Anirban Maitra ◽  
Charles F. Timmons ◽  
Momin T. Siddiqui ◽  
M. Hossein Saboorian

Abstract Giant cell fibroblastoma is an unusual tumor of childhood, primarily occurring in the superficial soft tissues. We describe the fine-needle aspiration biopsy features of a case of giant cell fibroblastoma of the chest wall in a 3-year-old child. The aspirates comprised bland spindle to oval cells entrapped in a metachromatic matrix, accompanied by rare multinucleated giant cells with wreathlike nuclei. Although we were unable to render a definitive diagnosis on fine-needle aspiration biopsy, surgical resection of the mass established the diagnosis of giant cell fibroblastoma. We review the distinctive cytologic features of some common soft tissue tumors arising in this age group that may give rise to a diagnostic conundrum on fine-needle aspiration biopsy.


2018 ◽  
Vol 62 (3) ◽  
pp. 231-233 ◽  
Author(s):  
Deepika Savant ◽  
Michael Adler ◽  
Leonard Kahn ◽  
Rubina Cocker

Objective: Amyloidomas are tumor-like deposits of amyloid. Amyloidoma of the gastrointestinal tract is rare. To the best of our knowledge, this is the first instance of diagnosis of an amyloidoma in the gastrointestinal tract by fine needle aspiration (FNA). Study Design: We report a case of a 64-year-old male with a history of ulcerative colitis and primary sclerosing cholangitis who was incidentally found to have a mass in the stomach wall. Results: Initially thought to be gastrointestinal stromal tumor, FNA demonstrated the lesion to be amyloidoma with a prominent giant cell reaction. This was further confirmed by mass spectrometry. This is the only case report of diagnosis of a gastric amyloidoma by FNA. Conclusion: The presence of a florid giant cell reaction in the absence of ulceration or an inflammatory or neoplastic lesion should alert the pathologist to the possibility of an amyloidoma. This is the only case report of diagnosis of a gastric amyloidoma by FNA.


2017 ◽  
Vol 61 (2) ◽  
pp. 160-164 ◽  
Author(s):  
Zimin Zhao ◽  
Cherie Paquette ◽  
Akeesha A. Shah ◽  
Kristen A. Atkins ◽  
Henry F. Frierson

Background: Tenosynovial giant cell tumor (TSGCT), also known as giant cell tumor of tendon sheath or pigmented villonodular synovitis, is the most common benign tumor of the tendon and synovium. The intra-articular diffuse type can present as a large infiltrative mass involving adjacent soft tissue and sometimes causes secondary destruction of bone, which leads to radiographic and clinical concern for malignancy. The tumor may also be purely extra-articular. Case: Here, we report the fine needle aspiration cytology findings of 2 cases of diffuse-type TSGCT with large mononuclear cells with eccentric nuclei, finely granular cytoplasm, and a peripheral well-defined cytoplasmic rim of hemosiderin (“ladybird cells”). Conclusion: Although the presence of ladybird cells has been described in tissue sections of TSGCT, their identification in cytological specimens has not been reported to our knowledge. When observed, their presence may aid in differentiating TSGCT from other lesions with multinucleated osteoclast-type giant cells occurring at or near joints.


2018 ◽  
Vol 46 (10) ◽  
pp. 879-882 ◽  
Author(s):  
Xiaorong Zhang ◽  
Xianglan Zhu ◽  
Jinnan Li ◽  
Nian Liu ◽  
Qiyuan Li ◽  
...  

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