Fine-needle aspiration of parotid gland schwannomas mimicking pleomorphic adenoma: A report of two cases

2003 ◽  
Vol 30 (1) ◽  
pp. 39-40 ◽  
Author(s):  
L. Assad ◽  
D. Treaba ◽  
R. Ariga ◽  
C. Bengana ◽  
S. Kapur ◽  
...  
CytoJournal ◽  
2015 ◽  
Vol 12 ◽  
pp. 7 ◽  
Author(s):  
Theresa Scognamiglio ◽  
Rohan Joshi ◽  
William I. Kuhel ◽  
Sana O. Tabbara ◽  
M. Katayoon Rezaei ◽  
...  

Carcinoma ex pleomorphic adenoma (CXPA) is a rare epithelial malignancy that arises from a primary or recurrent pleomorphic adenoma (PA). It may be noninvasive (NI) or invasive. NI CXPA is extremely rare. Preoperative diagnosis on fine needle aspiration (FNA) of CXPA may be difficult and poses a diagnostic challenge to clinicians and pathologists. Herein, we describe the FNA findings of a case of NI-CXPA. A 69-year-old woman presented with rapid enlargement of a stable parotid mass of 25 years. Cytologically, malignant cells were focally associated with metachromatic fibromyxoid matrix that was homogeneous and dense with a vague fibrillary quality. There were cell groups, papillary-like clusters and single malignant cells. The nuclei were pleomorphic with irregularly dispersed chromatin, and the cytoplasm was ill-defined and granular. Nucleoli were small to inconspicuous. Mitoses and necrosis were not seen. Cytological features were not specific for any type of salivary gland carcinoma. The FNA diagnosis was primary high-grade adenocarcinoma of the parotid gland, not otherwise specified. Facial nerve-sparing total parotidectomy was performed, which histologically showed PA interspersed with ducts and nests composed of pleomorphic atypical nuclei surrounded by extensive hyalinization. Single cells were also noted. No capsular infiltration was seen in the entirely sampled tumor. Immunohistochemistry for Ki-67 showed a higher proliferation rate in the malignant ducts and p63 positive cells focally surrounded some of the malignant ducts. Histological diagnosis was NI-CXPA. Accurate diagnosis is important for proper surgical management; however, the preoperative diagnosis of NI-CXPA is difficult to make on FNA.


2021 ◽  
pp. 014556132110221
Author(s):  
Bouatay Rachida ◽  
Ons Kharrat ◽  
Wiem Boughzala ◽  
Seifeddine Ben Hammouda ◽  
Nouha Ben Abdeljelil ◽  
...  

We report the case of a 10-year-old girl with a painless slowly growing mass that had developed over the course of 2 years in the left submandibular area. Physical examination revealed a firm painless submandibular mass with no other associated signs. Ultrasound graphics were in favor of a sebaceous cyst. Fine-needle aspiration and magnetic resonance images (MRI) concluded to a pleomorphic adenoma of the submandibular gland. The patient underwent left submandibulectomy. Histopathological examination confirmed the diagnosis of pleomorphic adenoma arising from the submandibular gland. The postoperative course was uneventful. Pleomorphic adenoma of the submandibular gland represents a diagnostic and therapeutic dilemma in children. Preoperative evaluation, including MRI and fine-needle aspiration, is recommended. Total submandibulectomy is also recommended to minimize recurrences and to avoid malignant transformation.


2013 ◽  
Vol 7 (4) ◽  
pp. 409-415 ◽  
Author(s):  
Alfredo E. Romero-Rojas ◽  
Julio A. Diaz-Perez ◽  
Deirdre Amaro ◽  
Alfonso Lozano-Castillo ◽  
Sandra I. Chinchilla-Olaya

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