scholarly journals Long‐term trajectories and current BMI are associated with poorer cognitive functioning in middle‐aged adults at high Alzheimer's disease risk

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Rebecca K. West ◽  
Ramit Ravona‐Springer ◽  
Inbal Sharvit‐Ginon ◽  
Ithamar Ganmore ◽  
Sigalit Manzali ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Functioning ◽  
Disease Risk ◽  
Middle Aged ◽  
Middle Aged Adults

Long‐term adiposity is associated with poorer cognitive performance in middle‐aged adults at high risk of Alzheimer’s disease

2020 ◽  
Vol 16 (S10) ◽  
Author(s):  
Rebecca West ◽  
Ramit Ravona‐Springer ◽  
Inbal Sharvit‐Ginon ◽  
Sapir Golan ◽  
Anthony Heymann ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
High Risk ◽  
Cognitive Performance ◽  
Middle Aged ◽  
Middle Aged Adults

scholarly journals APOE Ɛ4 genotype is associated with thicker retinal layers in asymptomatic middle‐aged adults at high Alzheimer’s disease risk

2021 ◽  
Vol 17 (S5) ◽  
Author(s):  
Inbal Sharvit‐Ginon ◽  
Michal Schnaider Beeri ◽  
Aron Weller ◽  
Ifat Sher ◽  
Ygal Rotenstreich ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Disease Risk ◽  
Middle Aged ◽  
Retinal Layers ◽  
Middle Aged Adults

scholarly journals P4-573: PROXIMITY TO PARENTAL ONSET AND APOE ε4 INDEPENDENTLY CONTRIBUTE TO AMYLOID BURDEN IN MIDDLE-AGED ADULTS WITH A FAMILY HISTORY OF SPORADIC ALZHEIMER'S DISEASE

2019 ◽  
Vol 15 ◽  
pp. P1539-P1539
Author(s):  
Eider M. Arenaza-Urquijo ◽  
Gemma Salvadó ◽  
Carolina Minguillón ◽  
Marta Crous-Bou ◽  
Gonzalo Sánchez-Benavides ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Family History ◽  
Amyloid Burden ◽  
Middle Aged ◽  
Sporadic Alzheimer’S Disease ◽  
Apoe Ε4 ◽  
History Of ◽  
Middle Aged Adults

scholarly journals Long-term effects of intracranial islet grafting on cognitive functioning in a rat metabolic model of sporadic Alzheimer's disease-like dementia

PLoS ONE ◽  
2020 ◽  
Vol 15 (1) ◽  
pp. e0227879
Author(s):  
Konstantin Bloch ◽  
Shay Henry Hornfeld ◽  
Shira Dar ◽  
Alexey Vanichkin ◽  
Irit Gil-Ad ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Functioning ◽  
Metabolic Model ◽  
Long Term Effects ◽  
Sporadic Alzheimer’S Disease

IC-P-018: VERBAL FLUENCY MEASURES ARE ASSOCIATED WITH ALZHEIMER'S DISEASE BIOMARKERS IN CLINICALLY UNIMPAIRED LATE MIDDLE-AGED ADULTS FROM THE WISCONSIN REGISTRY FOR ALZHEIMER'S PREVENTION

2006 ◽  
Vol 14 (7S_Part_1) ◽  
pp. P23-P24 ◽  
Author(s):  
Kimberly D. Mueller ◽  
Samantha L. Allison ◽  
Rebecca L. Koscik ◽  
Erin Jonaitis ◽  
Brad T. Christian ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Verbal Fluency ◽  
Middle Aged ◽  
Disease Biomarkers ◽  
Middle Aged Adults

scholarly journals Weight loss predicts Alzheimer’s disease biomarker positivity in cognitively unimpaired middle‐aged adults

2020 ◽  
Vol 16 (S10) ◽  
Author(s):  
Oriol Grau‐Rivera ◽  
Irene Navalpotro ◽  
Gonzalo Sánchez‐Benavides ◽  
Marc Suárez‐Calvet ◽  
Marta Milà‐Alomà ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Weight Loss ◽  
Middle Aged ◽  
Disease Biomarker ◽  
Middle Aged Adults

Do Worries About Cognitive Functioning and Concerns About Developing Alzheimer’s Disease Affect Psychological Well-Being?

2016 ◽  
Vol 29 (8) ◽  
pp. 1271-1287 ◽  
Author(s):  
Stephen J. Cutler ◽  
Corina Brăgaru
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Functioning ◽  
Structural Equation ◽  
Older Persons ◽  
Structural Equation Models ◽  
Well Being ◽  
Psychological Well Being ◽  
Lagged Effects

Objective: The objective of this study is to determine if cognitive worries affect psychological well-being, if these effects are long-term, and if such concerns affect well-being more so among persons with a parent having Alzheimer’s disease (AD). Method: We used structural equation models with three waves of data collected from persons ages 40 to 60 at T1. We created summative scores on five indicators of concerns about cognitive functioning and worries about dementia. Well-being measures included depression, life satisfaction, stress, and mastery. Results: We found (a) cognitive worries at Waves 1, 2, and 3 were generally associated with lower levels of psychological well-being at each of these waves; (b) there was no evidence of long-term, lagged effects, and (c) these relationships were statistically similar across groups of adult children and controls. Discussion: Because concerns about cognitive functioning and developing AD are pervasive among middle-aged and older persons, practitioners should be aware of their potentially deleterious effect on psychological well-being.

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