Is rTMS effective for anxiety symptoms in major depressive disorder? An efficacy analysis comparing left‐sided high‐frequency, right‐sided low‐frequency, and sequential bilateral rTMS protocols

2019 ◽  
Vol 36 (8) ◽  
pp. 723-731 ◽  
Author(s):  
Leo Chen ◽  
Abdul‐Rahman Hudaib ◽  
Kate E. Hoy ◽  
Paul B. Fitzgerald
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
High Frequency ◽  
Low Frequency ◽  
Anxiety Symptoms ◽  
Major Depressive ◽  
Efficacy Analysis

scholarly journals A meta-analysis of the efficacy of vortioxetine in patients with major depressive disorder (MDD) and high levels of anxiety symptoms

2016 ◽  
Vol 206 ◽  
pp. 140-150 ◽  
Author(s):  
David S. Baldwin ◽  
Ioana Florea ◽  
Paula L. Jacobsen ◽  
Wei Zhong ◽  
George G. Nomikos
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Meta Analysis ◽  
Anxiety Symptoms ◽  
Major Depressive

scholarly journals High-frequency cognitive and mood assessment in major depressive disorder with wearable technology (Preprint)

2018 ◽  
Author(s):  
Francesca Cormack ◽  
Maggie McCue ◽  
Nick Taptiklis ◽  
Caroline Skirrow ◽  
Emilie Glazer ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Cognitive Function ◽  
Depressive Disorder ◽  
Symptom Severity ◽  
High Frequency ◽  
Depression Symptom ◽  
Cognitive Assessments ◽  
Major Depressive ◽  
Good Correspondence ◽  
Adequate Treatment

BACKGROUND Cognitive symptoms are common in major depressive disorder, and may help to identify patients that need treatment or who are not experiencing adequate treatment response. Digital tools to provide real time data assessing cognitive function could help to support patients treatment and remediation of cognitive and mood symptoms. OBJECTIVE This study examined adherence, feasibility, and validity of a wearable high-frequency cognitive and mood assessment app over 6 weeks, corresponding to when antidepressant pharmacotherapy begins to show efficacy. METHODS Thirty patients (aged 19−63; 19 women) with mild-moderate depression participated. The new Cognition Kit application was delivered via the Apple Watch, providing a high-resolution touch screen display for task presentation and logging responses. Cognition was assessed by the n-back task up to 3 times daily and depressed mood by 3 short questions once daily. Selected tests sensitive to depression from the Cambridge Neuropsychological Test Automated Battery and validated questionnaires of depression symptom severity were administered on 4 occasions (baseline, weeks 1, 3, and 6). Adherence was defined as participants completing at least one assessment daily. RESULTS Adherence was excellent for mood and cognitive assessments (95% and 96%, respectively), did not deteriorate over time, and was not influenced by depression symptom severity or cognitive function at study onset. Daily mood assessments showed good correspondence with validated depression questionnaires (correlations range from .45 to .69 for total daily mood score) and daily cognitive assessments showed good correspondence with cognitive tests sensitive to depression (correlations ranged from .37 to .50 for mean n-back). CONCLUSIONS The study supports the feasibility and validity of high-frequency assessment of cognitive function and mood function using wearable devices over an extended period in patients with major depressive disorder. CLINICALTRIAL clinicaltrials.gov NCT03067506

Influence of comorbid anxiety symptoms on cognitive deficits in patients with major depressive disorder

2020 ◽  
Vol 260 ◽  
pp. 91-96 ◽  
Author(s):  
Jin Liu ◽  
Qiangli Dong ◽  
Xiaowen Lu ◽  
Jinrong Sun ◽  
Liang Zhang ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Cognitive Deficits ◽  
Anxiety Symptoms ◽  
Major Depressive ◽  
Comorbid Anxiety

Psychic and somatic anxiety symptoms as predictors of response to fluoxetine in major depressive disorder

2008 ◽  
Vol 161 (1) ◽  
pp. 116-120 ◽  
Author(s):  
George I. Papakostas ◽  
Patrick McGrath ◽  
Jonathan Stewart ◽  
Dana Charles ◽  
Ying Chen ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Anxiety Symptoms ◽  
Major Depressive ◽  
Somatic Anxiety ◽  
Predictors Of Response
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