scholarly journals Finding factors that predict treatment-resistant depression: Results of a cohort study

2018 ◽  
Vol 35 (7) ◽  
pp. 668-673 ◽  
Author(s):  
M. Soledad Cepeda ◽  
Jenna Reps ◽  
Patrick Ryan
Keyword(s):  
Cohort Study ◽  
Treatment Resistant Depression ◽  
Treatment Resistant ◽  
Resistant Depression

scholarly journals Cause-specific life years lost in individuals with treatment-resistant depression: A Danish nationwide register-based cohort study

2021 ◽  
Vol 280 ◽  
pp. 250-257
Author(s):  
Kathrine Bang Madsen ◽  
Oleguer Plana-Ripoll ◽  
Katherine L. Musliner ◽  
Jean-Christophe Philippe Debost ◽  
Liselotte Vogdrup Petersen ◽  
...  
Keyword(s):  
Cohort Study ◽  
Treatment Resistant Depression ◽  
Treatment Resistant ◽  
Life Years ◽  
Life Years Lost ◽  
Resistant Depression

Socio-demographic and clinical risk factors of treatment-resistant depression: A Danish population-based cohort study

2020 ◽  
Vol 261 ◽  
pp. 221-229 ◽  
Author(s):  
Frederikke Hordam Gronemann ◽  
Martin Balslev Jorgensen ◽  
Merete Nordentoft ◽  
Per Kragh Andersen ◽  
Merete Osler
Keyword(s):  
Risk Factors ◽  
Cohort Study ◽  
Population Based ◽  
Clinical Risk Factors ◽  
Treatment Resistant Depression ◽  
Treatment Resistant ◽  
Danish Population ◽  
Clinical Risk ◽  
Resistant Depression

scholarly journals Transcranial pulsed electromagnetic fields for treatment-resistant depression: A multicenter 8-week single-arm cohort study

2020 ◽  
Vol 63 (1) ◽  
Author(s):  
Erik Roj Larsen ◽  
Rasmus W. Licht ◽  
René Ernst Nielsen ◽  
Annette Lolk ◽  
Bille Borck ◽  
...  
Keyword(s):  
Cohort Study ◽  
Antidepressant Treatment ◽  
Treatment Options ◽  
Depression Scale ◽  
Antidepressant Effect ◽  
Hamilton Depression Scale ◽  
Treatment Resistant Depression ◽  
Treatment Resistant ◽  
Resistant Depression ◽  
Pulsed Electromagnetic

Abstract Background. The efficacy of antidepressant treatment is fair, but the efficacy is considerably lower in patients failing two or more trials underscoring the need for new treatment options. Our study evaluated the augmenting antidepressant effect of 8-weeks transcranial pulsed electromagnetic field (T-PEMF) therapy in patients with treatment-resistant depression. Methods. A multicenter 8-week single-arm cohort study conducted by the Danish University Antidepressant Group. Results. In total, 58 participants (20 men and 38 women) with a moderate to severe depression as part of a depressive disorder according to ICD-10 who fulfilled criteria for treatment resistance were included, with 19 participants being nonresponders to electroconvulsive therapy during the current depressive episode. Fifty-two participants completed the study period. Scores on the Hamilton Depression Scale 17-items version (HAM-D17) decreased significantly from baseline (mean = 20.6, SD 4.0) to endpoint (mean = 12.6, SD 7.1; N = 58). At endpoint, utilizing a Last Observation Carried Forward analysis, 49 and 28% of those participants with, respectively, a nonchronic current episode (≤2 years; N = 33) and a chronic current episode (>2 years; N = 25) were responders, that is, achieved a reduction of 50% or more on the HAM-D17 scale. At endpoint, respectively, 30 and 16% obtained remission, defined as HAM-D17 ≤ 7. On the Hamilton Scale 6-item version (HAM-D6), respectively, 51 and 16% obtained remission, defined as HAM-D6 ≤ 4. Conclusions. The findings indicate a potential beneficial role of T-PEMF therapy as an augmentation treatment to ongoing pharmacotherapy in treatment-resistant depression.

scholarly journals Treatment‐resistant depression as risk factor for substance use disorders—a nation‐wide register‐based cohort study

Addiction ◽  
2019 ◽  
Vol 114 (7) ◽  
pp. 1274-1282 ◽  
Author(s):  
Philip Brenner ◽  
Lena Brandt ◽  
Gang Li ◽  
Allitia DiBernardo ◽  
Robert Bodén ◽  
...  
Keyword(s):  
Substance Use ◽  
Risk Factor ◽  
Cohort Study ◽  
Substance Use Disorders ◽  
Treatment Resistant Depression ◽  
Treatment Resistant ◽  
Resistant Depression
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