Diagnostic interview assessed neuropsychiatric disorder comorbidity in 334 individuals with obsessive-compulsive disorder

2004 ◽  
Vol 19 (3) ◽  
pp. 163-173 ◽  
Author(s):  
V. Holland LaSalle ◽  
Kiara R. Cromer ◽  
Kathryn N. Nelson ◽  
Diane Kazuba ◽  
Lucy Justement ◽  
...  
CNS Spectrums ◽  
2006 ◽  
Vol 11 (1) ◽  
pp. 21-25 ◽  
Author(s):  
Prakash S. Masand ◽  
Nancy J. Keuthen ◽  
Sanjay Gupta ◽  
Subhdeep Virk ◽  
Barbara Yu-Siao ◽  
...  

ABSTRACTIntroduction:Irritable bowel syndrome (IBS) occurs more frequently in psychiatric patients, especially those with anxiety and mood disorders.Methods:We sought to determine the prevalence and phenomenology of IBS in patients diagnosed with obsessive-compulsive disorder (OCD). A semi-structured diagnostic interview was administered to patients seeking treatment for OCD in outpatient settings. Structured questions regarding gastrointestinal functioning and IBS symptoms were administered. IBS was diagnosed by a gastroenterologist using Rome I criteria.Results:Thirty-seven patients (35.1%) with OCD met criteria for IBS. Of these, 53.8% had IBS with both diarrhea and constipation, 30.8% had diarrhea-predominant IBS, and 15.4% had constipation-predominant IBS.The prevalence rate of IBS in an age- and sex-matched control group (n=40) of medical patients in a family practice was 2.5%. IBS prevalence rates were significantly higher for OCD patients than control subjects (P=.0002).Conclusion:IBS and psychiatric illness have high rates of bi-directional comorbidity. This study shows that 35.1% of patients with OCD satisfied criteria for IBS in contrast to 2.5% of the controlled subjects. In most patients the IBS was characterized by both diarrhea and constipation. While taking the initial history clinicians should inquire about bowel symptoms in patients presenting with psychiatric illnesses, including OCD. SSRIs could potentially worsen such symptoms and lead to non-adherence.


2009 ◽  
Vol 40 (6) ◽  
pp. 989-997 ◽  
Author(s):  
C. de Bruijn ◽  
S. Beun ◽  
R. de Graaf ◽  
M. ten Have ◽  
D. Denys

BackgroundIn this study we compared subjects with obsessive and/or compulsive symptoms who did not meet all criteria for obsessive–compulsive disorder (OCD) (subthreshold subjects) to subjects with full-blown OCD and also to subjects without obsessions or compulsions.MethodThe data were derived from the Netherlands Mental Health Survey and Incidence Study (NEMESIS), a large representative sample of the general Dutch population (n=7076). Using the Composite International Diagnostic Interview, Version 1.1 (CIDI 1.1), three groups were distinguished: subjects without lifetime obsessions or compulsions (94.2%), subthreshold subjects (4.9%) and subjects with full-blown OCD according to DSM-III-R (0.9%). These three groups were compared on various items, including psychological vulnerability, health and functional status, psychiatric co-morbidity and seeking treatment.ResultsSubthreshold and OCD subjects had similar scores on the majority of the items measured. Thus, there was little difference between subthreshold and OCD subjects in health, functional status, psychological vulnerability and psychiatric co-morbidity. However, OCD and subthreshold subjects scored worse on most of these items when compared to the controls without obsessions or compulsions.ConclusionHaving obsessions and compulsions is associated with substantial suffering and disability. Most subjects with obsessions and/or compulsions are not diagnosed with OCD according to the DSM-III-R criteria although these subjects generally display similar consequences to full-blown OCD subjects. We recommend that these subthreshold cases receive special attention in the development of DSM-V.


2016 ◽  
Vol 3 (4) ◽  
Author(s):  
Rima Das ◽  
Souvik Raychaudhuri

Obsessive-Compulsive disorder (OCD) is a neuropsychiatric disorder prevalent in population worldwide. In the present study we investigated OCD patients from the state of West Bengal, India. Patients were evaluated for social adjustment using Rosenzweig PF test and severity of OCD using the Yale-Brown Obsessive Compulsive Scale (Y-BOCS). It was found that patients from urban areas had poor social adjustment compared to those from semirural areas. Rural population fared well in adjustment in spite of disease.


1998 ◽  
Vol 173 (S35) ◽  
pp. 2-6 ◽  
Author(s):  
P. E. Bebbington

Background Although the concept of obsessive-compulsive disorder (OCD) has long been established, research diagnostic criteria are relatively recent developments. This is partly because the symptoms of OCD occur in the context of other disorders and it is arguable to what extent they are relatively discrete phenomena.Method Review of the existing epidemiological surveys based on standardised instruments.Results Nine population surveys using the Diagnostic Interview Schedule have given data on OCD, with six-month prevalences ranging from 0.7 to 2.1%. The British National Survey of Psychiatric Morbidity based on the CIS – R gave a one-month prevalence of 1% in males and 1.5% in females. Community surveys show an excess of females and emphasise the early age of onset. Minor obsessional symptoms are considerably more common than OCD itself.Conclusions OCD is fairly rare in the general population, but causes considerable distress to those who suffer from it.


2011 ◽  
Vol 41 (12) ◽  
pp. 2495-2506 ◽  
Author(s):  
J. R. Grisham ◽  
M. A. Fullana ◽  
D. Mataix-Cols ◽  
T. E. Moffitt ◽  
A. Caspi ◽  
...  

BackgroundVery few longitudinal studies have evaluated prospective neurodevelopmental and psychosocial risk factors for obsessive–compulsive disorder (OCD). Furthermore, despite the heterogeneous nature of OCD, no research has examined risk factors for its primary symptom dimensions, such as contamination/washing.MethodPotential risk factors for symptoms or diagnosis of OCD in adulthood and for specific adult obsessive–compulsive (OC) symptom dimensions were examined in the Dunedin Study birth cohort. The presence of obsessions and compulsions and psychological disorders was assessed using the Diagnostic Interview Schedule (DIS) at ages 26 and 32 years. Individuals with a diagnosis of OCD at either age (n=36) were compared to both a healthy control group (n=613) and an anxious control group (n=310) to determine whether associations between a risk factor and an OCD diagnosis were specific.ResultsChildhood neurodevelopmental, behavioral, personality and environmental risk factors were associated with a diagnosis of OCD and with OC symptoms at ages 26 and 32. Social isolation, retrospectively reported physical abuse and negative emotionality were specific predictors of an adult OCD diagnosis. Of note, most risk factors were associated with OC symptoms in adulthood and several risk factors predicted specific OCD dimensions. Perinatal insults were linked to increased risk for symmetry/ordering and shameful thoughts dimensions, whereas poor childhood motor skills predicted the harm/checking dimension. Difficult temperament, internalizing symptoms and conduct problems in childhood also predicted specific symptom dimensions and lower IQ non-specifically predicted increased risk for most dimensions.ConclusionsThe current findings underscore the need for a dimensional approach in evaluating childhood risk factors for obsessions and compulsions.


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