Post-treatment effects of exposure therapy and clomipramine in obsessive-compulsive disorder

2004 ◽  
Vol 19 (4) ◽  
pp. 225-233 ◽  
Author(s):  
H. Blair Simpson ◽  
Michael R. Liebowitz ◽  
Edna B. Foa ◽  
Michael J. Kozak ◽  
Andrew B. Schmidt ◽  
...  
2018 ◽  
Vol 5 (1) ◽  
pp. 1461542
Author(s):  
Silje Elisabeth Hasmo Holm ◽  
Bjarne Hansen ◽  
Gerd Kvale ◽  
Thomas Eilertsen ◽  
Torun Grøtte ◽  
...  

Author(s):  
Jonathan S. Abramowitz ◽  
Brittain Mahaffey

In her commentary on our case description of Cassie, Dr. Beidel very thoughtfully raises a number of important points regarding the treatment of obsessive-compulsive disorder (OCD). And we agree with all of them. Dr. Beidel, however, raises two issues in particular that we wish to comment on further: (a) the origins of obsessional fears, and (b) the use of distraction in exposure therapy....


Author(s):  
Andrea Pozza ◽  
Gerhard Andersson ◽  
Paolo Antonelli ◽  
Davide Dèttore

AbstractCognitive behavioural treatments (CBTs) are well-established for obsessive compulsive disorder (OCD). However, few patients receive CBT, due to factors like geographical limitations, perceived stigmatization, and lack of CBT services. Some evidence suggests that computer-delivered cognitive-behavioural treatments (CCBTs) could be an effective strategy to improve patients’ access to CBT. To date a meta-analysis on effectiveness of CCBTs for OCD has not been conducted. The present study used meta-analytical techniques to summarize evidence on CCBTs for OCD on OCD and depression symptom outcomes at post-treatment and follow-up. A meta-analysis was conducted according to PRISMA guidelines. Treatments were classified as CCBTs if including evidence-based cognitive-behavioural components for OCD (psychoeducation, exposure and response prevention, cognitive restructuring), delivered through devices like computers, palmtops, telephone-interactive voice-response systems, CD-ROMS, and cell phones. Studies were included if they used validated outcomes for OCD. Eight studies met inclusion criteria (n= 392). A large effect favouring CCBTs over control conditions was found for OCD symptoms at post-treatment (d= 0.82,p= 0.001), but not for depression symptom outcomes (d= 0.15,p= 0.20). Theoretical implications and directions for research are discussed. A larger number of randomized controlled trials is required.


2010 ◽  
Vol 34 (1) ◽  
pp. 6-9 ◽  
Author(s):  
Colette Kearns ◽  
Yvonne Tone ◽  
Gavin Rush ◽  
James V. Lucey

Aims and methodTo establish whether cognitive-behavioural therapy (CBT) with response and exposure prevention (ERP) is effective in individuals with obsessive–compulsive disorder (OCD). Twenty-four patients with OCD, divided into four groups, participated in ten sessions of group CBT. All patients completed the Yale–Brown Obsessive–Compulsive Scale (Y-BOCS), the Maudsley Obsessive–Compulsive Inventory (MOCI), the Beck Depression Inventory (BDI) and the Beck Anxiety Inventory (BAI) pre- and post-treatment.ResultsThe mean (s.d.) YBOC score post-treatment was 17.1 (5.8). This was significantly lower than the mean (s.d.) YBOC pre-treatment (24.7 (6.1); t = 8.4, d.f. = 23, P < 0.005). A significant reduction was also observed in relation to all other rating scales.Clinical implicationsCognitive–behavioural therapy for OCD delivered in a group setting is a clinically effective and acceptable treatment for patients. The use of group-based CBT is an effective means to improve access to psychotherapy.


2009 ◽  
Vol 38 (2) ◽  
pp. 227-232 ◽  
Author(s):  
Elena Cabedo ◽  
Amparo Belloch ◽  
Carmen Carrió ◽  
Christina Larsson ◽  
Héctor Fernández-Alvarez ◽  
...  

Background: Very few studies have compared the efficacy of individual and group cognitive behaviour therapy (CBT) for the treatment of Obsessive-Compulsive Disorder (OCD) by taking into consideration the change in OCD severity in both the short and long term. Aims: To conduct an open trial of individual versus group CBT for OCD, comparing the clinical and statistically significant changes in severity both at post-treatment and one year later. Method: Forty-two OCD subjects were assigned to individual (n = 18) or group CBT (n = 24, in four groups). Sixteen and 22 subjects completed the treatment in the individual and group conditions, respectively. The Yale-Brown Obsessive Compulsive Scale was recorded at pre-treatment, post-treatment and at the one-year follow-up. Results: At the end of treatment, the clinically significant change was comparable for the two treatment conditions and remained stable at the one-year follow-up. Of the 16 participants who completed the individual CBT treatment, 68.75% were classified as recovered at post-treatment, compared to 40.9% of those receiving group CBT. At follow-up the rate of recovery decreased to 62.5% in individual CBT and to 31.8% in group CBT. Conclusions: Group CBT is effective in decreasing OCD severity. The post-treatment changes were maintained one year later. Nevertheless, these changes were higher in the individual delivery of CBT.


2011 ◽  
Vol 187 (1-2) ◽  
pp. 174-179 ◽  
Author(s):  
Amparo Belloch ◽  
Elena Cabedo ◽  
Carmen Carrió ◽  
Héctor Fernández-Alvarez ◽  
Fernando García ◽  
...  

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