Label‐free classification of dead and live colonic adenocarcinoma cells based on 2D light scattering and deep learning analysis

2021 ◽  
Author(s):  
Shuaiyi Li ◽  
Ya Li ◽  
Jianning Yao ◽  
Bing Chen ◽  
Jiayou Song ◽  
...  
Sensors ◽  
2021 ◽  
Vol 21 (24) ◽  
pp. 8360
Author(s):  
Xiwei Huang ◽  
Hyungkook Jeon ◽  
Jixuan Liu ◽  
Jiangfan Yao ◽  
Maoyu Wei ◽  
...  

The authors wish to make the following correction to their paper [...]


Sensors ◽  
2021 ◽  
Vol 21 (2) ◽  
pp. 512
Author(s):  
Xiwei Huang ◽  
Jixuan Liu ◽  
Jiangfan Yao ◽  
Maoyu Wei ◽  
Wentao Han ◽  
...  

The differential count of white blood cells (WBCs) is one widely used approach to assess the status of a patient’s immune system. Currently, the main methods of differential WBC counting are manual counting and automatic instrument analysis with labeling preprocessing. But these two methods are complicated to operate and may interfere with the physiological states of cells. Therefore, we propose a deep learning-based method to perform label-free classification of three types of WBCs based on their morphologies to judge the activated or inactivated neutrophils. Over 90% accuracy was finally achieved by a pre-trained fine-tuning Resnet-50 network. This deep learning-based method for label-free WBC classification can tackle the problem of complex instrumental operation and interference of fluorescent labeling to the physiological states of the cells, which is promising for future point-of-care applications.


2018 ◽  
Vol 11 (4) ◽  
pp. e201700244 ◽  
Author(s):  
Lana Woolford ◽  
Mingzhou Chen ◽  
Kishan Dholakia ◽  
C. Simon Herrington

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