scholarly journals An integrated enrichment system to facilitate isolation and molecular characterization of single cancer cells from whole blood

2018 ◽  
Vol 93 (12) ◽  
pp. 1226-1233 ◽  
Author(s):  
Liping Yu ◽  
Silin Sa ◽  
Ling Wang ◽  
Keely Dulmage ◽  
Neha Bhagwat ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Molecular Characterization ◽  
Whole Blood ◽  
Single Cancer

scholarly journals Molecular characterization of exosome-like vesicles from breast cancer cells

BMC Cancer ◽  
2014 ◽  
Vol 14 (1) ◽  
Author(s):  
Stefan Kruger ◽  
Zakaria Y Abd Elmageed ◽  
David H Hawke ◽  
Philipp M Wörner ◽  
David A Jansen ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Molecular Characterization ◽  
Breast Cancer Cells

scholarly journals Molecular characterization of type I IFN-induced cytotoxicity in bladder cancer cells reveals biomarkers of resistance

2021 ◽  
Author(s):  
Jennifer L. Green ◽  
Robin Osterhout ◽  
Amy L. Klova ◽  
Carsten Merkwirth ◽  
Scott R.P. McDonnell ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Cancer Cells ◽  
Molecular Characterization ◽  
Type I ◽  
Type I Ifn ◽  
Bladder Cancer Cells

scholarly journals Molecular characterization of FRAXB and comparative common fragile site instability in cancer cells

2001 ◽  
Vol 33 (1) ◽  
pp. 82-92 ◽  
Author(s):  
Martin F. Arlt ◽  
Diane E. Miller ◽  
David G. Beer ◽  
Thomas W. Glover
Keyword(s):  
Cancer Cells ◽  
Molecular Characterization ◽  
Fragile Site ◽  
Common Fragile Site

Abstract 252: Molecular characterization of cancer stem cells isolated from primary colon cancer cells.

2013 ◽  
Author(s):  
Martin Lange ◽  
Dirk Schumacher ◽  
Thomas Hauling ◽  
Christian Regenbrecht ◽  
Oliver Politz ◽  
...  
Keyword(s):  
Stem Cells ◽  
Colon Cancer ◽  
Cancer Stem Cells ◽  
Cancer Cells ◽  
Molecular Characterization ◽  
Colon Cancer Cells ◽  
Primary Colon Cancer ◽  
Primary Colon

Independent Prognostication and Therapy Monitoring of Breast Cancer Patients by Dna/Rna Typing of Minimal Residual Cancer Cells

2000 ◽  
Vol 15 (1) ◽  
pp. 94-99 ◽  
Author(s):  
M. Giesing ◽  
F. Austrup ◽  
B. BÖckmann ◽  
G. Driesel ◽  
C. Eder ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Cancer Patients ◽  
Molecular Characterization ◽  
Therapy Monitoring ◽  
Breast Cancer Patients ◽  
Residual Cancer ◽  
Minimal Residual Cancer ◽  
Minimal Residual

Clinical relevance, purification techniques and molecular characterization of minimal residual cancer cells (MRCC) is a controversial topic in the literature. An analytical concept including a novel isolation procedure and a panel of tests for DNA and RNA typing of MRCCs is described and clinically evaluated in this paper. The purification procedure exploiting the physical characteristics of MRCCs shows superior performance leading to >50% pure and viable tumor cells. Proof of the presence and purity of MRCCs in an isolated sample is given by multiparametric DNA typing (amplifications, mutations, losses of heterozygosity). On the basis of the proven presence of MRCCs tumor-relevant mRNAs can be adequately analyzed by normalized quantitative real-time RT-PCR. The molecular characterization of MRCCs isolated from blood of breast cancer patients could have a strong clinical impact on prognostication, drug targeting and therapy monitoring.

Molecular characterization of autophagic and apoptotic signaling induced by Sorafenib in liver cancer cells: In vitro and in vivo studies

2018 ◽  
Vol 68 ◽  
pp. S670-S671 ◽  
Author(s):  
M.Á. Rodríguez-Hernández ◽  
R. González ◽  
Á.J. De la Rosa ◽  
P. Gallego ◽  
L. Contreras ◽  
...  
Keyword(s):  
Liver Cancer ◽  
Cancer Cells ◽  
Molecular Characterization ◽  
In Vivo Studies ◽  
Apoptotic Signaling ◽  
Liver Cancer Cells

scholarly journals Epigenetic regulation and molecular characterization of C/EBPα in pancreatic cancer cells

2009 ◽  
Vol 124 (4) ◽  
pp. 827-833 ◽  
Author(s):  
Takashi Kumagai ◽  
Tadayuki Akagi ◽  
Julian C. Desmond ◽  
Norihiko Kawamata ◽  
Sigal Gery ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Cancer Cells ◽  
Molecular Characterization ◽  
Epigenetic Regulation ◽  
Pancreatic Cancer Cells

Microfluidic device for DNA amplification of single cancer cells isolated from whole blood by self-seeding microwells

Lab on a Chip ◽  
2015 ◽  
Vol 15 (22) ◽  
pp. 4331-4337 ◽  
Author(s):  
Yoonsun Yang ◽  
Hoon Suk Rho ◽  
Michiel Stevens ◽  
Arjan G. J. Tibbe ◽  
Han Gardeniers ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Microfluidic Device ◽  
Whole Blood ◽  
Dna Amplification ◽  
Single Cancer

We developed a microfluidic device in which single cancer cells can be placed, lysed and their DNA amplified for further interrogation.

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