Drugs in development for herpes simplex and varicella zoster virus

2017 ◽  
Vol 102 (1) ◽  
pp. 30-32 ◽  
Author(s):  
A Birkmann ◽  
H Zimmermann
Keyword(s):  
Herpes Simplex ◽  
Varicella Zoster Virus ◽  
Varicella Zoster

Herpes simplex virus and varicella zoster virus

2015 ◽  
Vol 28 (6) ◽  
pp. 589-595 ◽  
Author(s):  
Surjo K. De ◽  
Jennifer C.L. Hart ◽  
Judith Breuer
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Varicella Zoster Virus ◽  
Varicella Zoster ◽  
Simplex Virus

scholarly journals A Genome-Wide Comparative Evolutionary Analysis of Herpes Simplex Virus Type 1 and Varicella Zoster Virus

PLoS ONE ◽  
2011 ◽  
Vol 6 (7) ◽  
pp. e22527 ◽  
Author(s):  
Peter Norberg ◽  
Shaun Tyler ◽  
Alberto Severini ◽  
Rich Whitley ◽  
Jan-Åke Liljeqvist ◽  
...  
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Varicella Zoster Virus ◽  
Herpes Simplex Virus Type ◽  
Evolutionary Analysis ◽  
Varicella Zoster ◽  
Genome Wide ◽  
A Genome ◽  
Simplex Virus

Viable herpes simplex virus type 1 and varicella-zoster virus in the trigeminal ganglia of human cadavers

2013 ◽  
Vol 85 (5) ◽  
pp. 833-838 ◽  
Author(s):  
Hisako Saitoh ◽  
Yuko Momma ◽  
Hiroyuki Inoue ◽  
Daisuke Yajima ◽  
Hirotaro Iwase
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Varicella Zoster Virus ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Trigeminal Ganglia ◽  
Varicella Zoster ◽  
Human Cadavers ◽  
Simplex Virus

Herpesvirus Infections

2018 ◽  
Author(s):  
Martin S. Hirsch
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Varicella Zoster Virus ◽  
Ganglion Cells ◽  
Human Herpesvirus ◽  
Herpes Infection ◽  
Varicella Zoster ◽  
Clinical Syndromes ◽  
Simplex Virus ◽  
Human Herpesviruses

The herpes group of viruses is composed of at least eight human viruses and numerous animal viruses. The human herpesviruses include herpes simplex virus types 1 and 2 (HSV-1 and HSV-2), varicella-zoster virus (VZV), cytomegalovirus (CMV), Epstein-Barr virus (EBV), and human herpesvirus types 6 (HHV-6), 7 (HHV-7), and 8 (HHV-8, also known as Kaposi sarcoma–associated herpesvirus). Human herpesviruses share the properties of latency and reactivation. Members of the group can cause productive lytic infections, in which infectious virus is produced and cells are killed, or nonproductive lytic infections, in which viral DNA persists but complete replication does not occur and cells survive. After acute lytic infections, herpesviruses often persist in a latent form for years; periodic reactivations are followed by recurrent lytic infections. Sites of latency vary: HSV and VZV persist in neural ganglion cells, EBV persists in B cells, and CMV probably remains latent in many cell types. The sites of latency for HHV-6 and HHV-7 have not been identified, although both herpesviruses have been detected in salivary glands. All human herpesviruses have a worldwide distribution. Considerable efforts are being directed toward the development of vaccines and antiviral agents that will be active against herpesviruses. This chapter discusses the epidemiology, pathogenesis, diagnosis, prevention, and treatment of herpes simplex virus and varicella-zoster virus and their clinical syndromes. The descriptions of the clinical syndromes include complications and clinical features, as well as descriptions of symptoms. Tables provide information on chemotherapy for primary genital and mucocutaneous herpes infection, suppression of severe and recurring genital herpes infection, and varicella-zoster infection. Figures provide photographic illustrations of the various clinical syndromes. A sidebar about herpesvirus information on the Internet provides further detail. This review contains 123 references, 4 tables, and 6 highly rendered figures.

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