Magnetic Dextran Nanoparticles That Bear Hydrophilic Porphyrin Derivatives: Bimodal Agents for Potential Application in Photodynamic Therapy

ChemPlusChem ◽  
2015 ◽  
Vol 80 (9) ◽  
pp. 1416-1426 ◽  
Author(s):  
Jean-Pierre Mbakidi ◽  
Frédérique Brégier ◽  
Tan-Sothea Ouk ◽  
Robert Granet ◽  
Sandra Alves ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Potential Application ◽  
Porphyrin Derivatives

scholarly journals Magnetic Dextran Nanoparticles That Bear Hydrophilic Porphyrin Derivatives: Bimodal Agents for Potential Application in Photodynamic Therapy

ChemPlusChem ◽  
2015 ◽  
Vol 80 (9) ◽  
pp. 1367-1367
Author(s):  
Jean-Pierre Mbakidi ◽  
Frédérique Brégier ◽  
Tan-Sothea Ouk ◽  
Robert Granet ◽  
Sandra Alves ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Potential Application ◽  
Porphyrin Derivatives

Cover Picture: Magnetic Dextran Nanoparticles That Bear Hydrophilic Porphyrin Derivatives: Bimodal Agents for Potential Application in Photodynamic Therapy (ChemPlusChem 9/2015)

ChemPlusChem ◽  
2015 ◽  
Vol 80 (9) ◽  
pp. 1365-1365
Author(s):  
Jean-Pierre Mbakidi ◽  
Frédérique Brégier ◽  
Tan-Sothea Ouk ◽  
Robert Granet ◽  
Sandra Alves ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Potential Application ◽  
Porphyrin Derivatives

Potentiation of Systemic Anti-Tumor Immunity with Photodynamic Therapy Using Porphyrin Derivatives

2022 ◽  
pp. 279-344
Author(s):  
Catarina S. Lobo ◽  
Lígia C. Gomes-da-Silva ◽  
Luis G. Arnaut
Keyword(s):  
Photodynamic Therapy ◽  
Tumor Immunity ◽  
Porphyrin Derivatives

scholarly journals Semiconductor ZnO based photosensitizer core–shell upconversion nanoparticle heterojunction for photodynamic therapy

RSC Advances ◽  
2020 ◽  
Vol 10 (63) ◽  
pp. 38416-38423
Author(s):  
Yongmei Li ◽  
Yuemei Li ◽  
Yandong Bai ◽  
Rui Wang ◽  
Laixiang Lin ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Tumor Cell ◽  
Potential Application ◽  
Thyroid Tumor ◽  
Core Shell

NaErF4@ZnO UCNPs for potential application in thyroid tumor cell PDT.

RGD-Porphyrin Conjugates: Synthesis and Potential Application in Photodynamic Therapy

2003 ◽  
Vol 2003 (8) ◽  
pp. 1486-1493 ◽  
Author(s):  
Vincent Chaleix ◽  
Vincent Sol ◽  
Yi-Ming Huang ◽  
Michel Guilloton ◽  
Robert Granet ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Potential Application

Lactose-conjugated porphyrin: Synthesis and photobiological evaluation as potential agents for photodynamic therapy

2021 ◽  
Author(s):  
Yue Cao ◽  
Xin Zhang ◽  
Bo Ren ◽  
Xiaodong Yang
Keyword(s):  
Photodynamic Therapy ◽  
Water Solubility ◽  
Application Range ◽  
Porphyrin Derivatives ◽  
The Poor ◽  
Specific Cytotoxicity ◽  
Tumor Selectivity ◽  
Porphyrin Synthesis

Porphyrin-based photosensitizers are conventional photodynamic agents applied in clinic. However, their clinic application has been overshadowed by the poor water solubility. In addition, they have weak tumor selectivity, which may cause undesirable side effects. The preparation of novel porphyrin derivatives has been explored for the potential application in photodynamic therapy (PDT). To achieve this goal, lactose-conjugated porphyrin nanoparticles (Lac-PorNPs) has been synthesized and characterized. PDT with Lac-PorNPs exhibits tumor-specific cytotoxicity in lactose receptor overexpressed HepG2 cells in vitro and in vivo. In summary, we designed and synthesized lactose conjugates porphyrin with enhanced water-solubility and tumor selectivity. This work expanded the application range of porphyrin-based photosensitizers for cancer treatment.

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