scholarly journals Mechanics and Function of the Pulmonary Vasculature: Implications for Pulmonary Vascular Disease and Right Ventricular Function

Author(s):  
Steven Lammers ◽  
Devon Scott ◽  
Kendall Hunter ◽  
Wei Tan ◽  
Robin Shandas ◽  
...  
2020 ◽  
Vol 9 (1) ◽  
pp. 23
Author(s):  
Zhongshuang Zhang ◽  
Xiaoyong Song ◽  
Zhengyong Zhao ◽  
Jiazheng Xu ◽  
Shu Luo ◽  
...  

Pulmonary hypertension is called PH for short. It is caused by the pulmonary artery vascular disease leading to pulmonary vascular resistance, and the increase right lung compartment load, which resulting in weakening or even collapse of the right ventricular function. The establishment of rat PH model under the action of monocrotaline is a repeatable, simple and accessible operation technique, which has been widely used in the treatment of pulmonary hypertension. This paper discusses the principle and properties of the PH model on rats under the monocrotaline action.


2005 ◽  
Vol 15 (S1) ◽  
pp. 48-50 ◽  
Author(s):  
Robert J. Boucek Jr ◽  
Richard Martinez

With advances in surgical technique, more children with complex congenital heart disease are surviving.1 Increasingly, attention is focusing on late morbidities, such as right ventricular dysfunction.2 For many common forms of congenital cardiac malformations, the assessment of right ventricular size and function is now essential so as to make optimal decisions concerning management.3 Commonly encountered examples include the timing for operative replacement of the incompetent pulmonary valve following surgical repair of tetralogy of Fallot, and the assessment of suspected ventricular dysfunction in children with functionally single or systemic right ventricles.4 Echocardiography remains the most practical method for serially determining right ventricular function, despite its limitations.5 The easy accessibility of echocardiography has encouraged its continued development as a tool for determining right ventricular function in neonates, infants, and children. A comparison of values established for the right ventricle is shown in Table 1, along with the references from which they were culled. We will describe these values in sequence.


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