A DFT Study on the Binuclear Copper(I)‐Catalyzed Synthesis Mechanism of 1,2,3‐Triazolo[1,5‐c]Pyrimidines via Interrupted Click and Ketenimine Rearrangement

ChemPhysChem ◽  
2021 ◽  
Author(s):  
Zhaoman Zhou ◽  
Qianqian Yue ◽  
Yanying Zhao
Keyword(s):  
Dft Study ◽  
Binuclear Copper ◽  
Synthesis Mechanism

Double azido-bridged and mixed-bridged binuclear copper(II) and nickel(II) compounds with N,N,O-donor Schiff bases: Synthesis, structure, magnetic and DFT study

Polyhedron ◽  
2015 ◽  
Vol 89 ◽  
pp. 49-54 ◽  
Author(s):  
Partha Pratim Chakrabarty ◽  
Sanjib Giri ◽  
Dieter Schollmeyer ◽  
Hiroshi Sakiyama ◽  
Masahiro Mikuriya ◽  
...  
Keyword(s):  
Schiff Bases ◽  
Dft Study ◽  
Binuclear Copper

DFT Study of Benzofuroxan Synthesis Mechanism from 2-Nitroaniline via Sodium Hypochlorite

2010 ◽  
Vol 23 (4) ◽  
pp. 387-392 ◽  
Author(s):  
Chun-yuan Hou ◽  
Xiao-fang Chen ◽  
Jian-yong Liu ◽  
Wei-peng Lai ◽  
Bo-zhou Wang
Keyword(s):  
Sodium Hypochlorite ◽  
Dft Study ◽  
Synthesis Mechanism

DFT study of the effect of hidrocarbonated chains on the electronic properties of some oligothiophene derivatives

2009 ◽  
Author(s):  
Manuel Fernández-Gómez ◽  
Amparo Navarro ◽  
MªPaz Fernández-Liencres ◽  
Mónica Moral ◽  
José Manuel Granadino-Roldán ◽  
...  
Keyword(s):  
Electronic Properties ◽  
Dft Study

4H-1,3-Benzothiazin-4-one a Promising Class Against MDR/XDR-TB

2019 ◽  
Vol 19 (8) ◽  
pp. 567-578 ◽  
Author(s):  
Marcus Vinicius Nora de Souza ◽  
Thais Cristina Mendonça Nogueira
Keyword(s):  
Treatment Time ◽  
Public Health Problem ◽  
New Drugs ◽  
Global Public Health ◽  
Synthesis Mechanism ◽  
Highly Active ◽  
Latent Disease ◽  
Resistant Strains ◽  
Chemical Class ◽  
Global Public Health Problem

Nowadays, tuberculosis (TB) is an important global public health problem, being responsible for millions of TB-related deaths worldwide. Due to the increased number of cases and resistance of Mycobacterium tuberculosis to all drugs used for the treatment of this disease, we desperately need new drugs and strategies that could reduce treatment time with fewer side effects, reduced cost and highly active drugs against resistant strains and latent disease. Considering that, 4H-1,3-benzothiazin-4-one is a promising class of antimycobacterial agents in special against TB-resistant strains being the aim of this review the discussion of different aspects of this chemical class such as synthesis, mechanism of action, medicinal chemistry and combination with other drugs.

Sign in / Sign up

Export Citation Format

Share Document