scholarly journals Role of the Methoxy Groups in Cryptophanes for Complexation of Xenon: Conformational Selection Evidence from 129 Xe-1 H NMR SPINOE Experiments

ChemPhysChem ◽  
2017 ◽  
Vol 18 (12) ◽  
pp. 1561-1568 ◽  
Author(s):  
Patrick Berthault ◽  
Céline Boutin ◽  
Estelle Léonce ◽  
Erwann Jeanneau ◽  
Thierry Brotin
Keyword(s):  
Conformational Selection ◽  
H Nmr ◽  
Methoxy Groups

scholarly journals Dietary starch promotes hepatic lipogenesis in barramundi (Lates calcarifer)

2020 ◽  
Vol 124 (4) ◽  
pp. 363-373
Author(s):  
N. M. Wade ◽  
L. H. Trenkner ◽  
I. Viegas ◽  
L. C. Tavares ◽  
M. Palma ◽  
...  
Keyword(s):  
Mammalian Target Of Rapamycin ◽  
Sea Bass ◽  
Metabolic Effects ◽  
Lates Calcarifer ◽  
Glucose Levels ◽  
H Nmr ◽  
Expression Of Genes ◽  
Fractional Synthetic Rate ◽  
Dietary Starch

AbstractBarramundi (Lates calcarifer) are a highly valued aquaculture species, and, as obligate carnivores, they have a demonstrated preference for dietary protein over lipid or starch to fuel energetic growth demands. In order to investigate how carnivorous fish regulate nutritional cues, we examined the metabolic effects of feeding two isoenergetic diets that contained different proportions of digestible protein or starch energy. Fish fed a high proportion of dietary starch energy had a higher proportion of liver SFA, but showed no change in plasma glucose levels, and few changes in the expression of genes regulating key hepatic metabolic pathways. Decreased activation of the mammalian target of rapamycin growth signalling cascade was consistent with decreased growth performance values. The fractional synthetic rate (lipogenesis), measured by TAG 2H-enrichment using 2H NMR, was significantly higher in barramundi fed with the starch diet compared with the protein diet (0·6 (se 0·1) v. 0·4 (se 0·1) % per d, respectively). Hepatic TAG-bound glycerol synthetic rates were much higher than other closely related fish such as sea bass, but were not significantly different (starch, 2·8 (se 0·3) v. protein, 3·4 (se 0·3) % per d), highlighting the role of glycerol as a metabolic intermediary and high TAG-FA cycling in barramundi. Overall, dietary starch significantly increased hepatic TAG through increased lipogenesis. Compared with other fish, barramundi possess a unique mechanism to metabolise dietary carbohydrates and this knowledge may define ways to improve performance of advanced formulated feeds.

The role of Al in C–S–H: NMR, XRD, and compositional results for precipitated samples

2006 ◽  
Vol 36 (1) ◽  
pp. 18-29 ◽  
Author(s):  
G.K. Sun ◽  
J. Francis Young ◽  
R. James Kirkpatrick
Keyword(s):  
H Nmr

The Role of Methoxy Groups in Methanol to Olefin Conversion

2008 ◽  
Vol 112 (7) ◽  
pp. 2685-2688 ◽  
Author(s):  
Zhi-Min Cui ◽  
Qiang Liu ◽  
Shao-Wei Bain ◽  
Zhuo Ma ◽  
Wei-Guo Song
Keyword(s):  
Olefin Conversion ◽  
Methanol To Olefin ◽  
Methoxy Groups

Atropisomerism of biphenyl compounds. An Important role of o-substituted methoxy groups and fluorine atoms

1981 ◽  
Vol 46 (2) ◽  
pp. 389-392 ◽  
Author(s):  
Nobusuke Kawano ◽  
Masayoshi Okigawa ◽  
Noriko Hasaka ◽  
Isao Kouno ◽  
Yasuko Kawahara ◽  
...  
Keyword(s):  
Methoxy Groups

scholarly journals Essential role of conformational selection in ligand binding

2014 ◽  
Vol 186 ◽  
pp. 13-21 ◽  
Author(s):  
Austin D. Vogt ◽  
Nicola Pozzi ◽  
Zhiwei Chen ◽  
Enrico Di Cera
Keyword(s):  
Ligand Binding ◽  
Essential Role ◽  
Conformational Selection

scholarly journals Treatment Effects of Ischemic Stroke by Berberine, Baicalin, and Jasminoidin from Huang-Lian-Jie-Du-Decoction (HLJDD) Explored by an Integrated Metabolomics Approach

2017 ◽  
Vol 2017 ◽  
pp. 1-20 ◽  
Author(s):  
Qian Zhang ◽  
Xiaowei Fu ◽  
Junsong Wang ◽  
Minghua Yang ◽  
Lingyi Kong
Keyword(s):  
Ischemic Stroke ◽  
Treatment Effects ◽  
Infarct Volume ◽  
Artery Occlusion ◽  
H Nmr ◽  
Abnormal Metabolism ◽  
Cerebral Artery Occlusion ◽  
First Time ◽  
Integrated Metabolomics

Berberine, baicalin, and jasminoidin were major active ingredients of Huang-Lian-Jie-Du-Decoction (HLJDD), a famous prescription of traditional Chinese medicine (TCM), which has been used for the treatment of ischemic stroke. The aim of the present study was to classify their roles in the treatment effects of ischemic stroke. A rat model of middle cerebral artery occlusion (MCAO) was constructed to mimic ischemic stroke and treatment effects of berberine, baicalin, and jasminoidin, and HLJDD was assessed by neurologic deficit scoring, infarct volume, histopathology, immunohistochemistry, biochemistry, quantitative real-time polymerase chain reaction (qRT-PCR), and Western blotting. In addition, the 1H NMR metabolomics approach was used to assess the metabolic profiles, which combined with correlation network analysis successfully revealed metabolic disorders in ischemic stroke concerning the treatment of the three principal compounds from HLJDD for the first time. The combined results suggested that berberine, baicalin, and jasminoidin are responsible for the effectiveness of HLJDD on the treatment of ischemic stroke by amelioration of abnormal metabolism and regulation of oxidative stress, neuron autophagy, and inflammatory response. This integrated metabolomics approach showed its potential in understanding the function of complex formulae and clarifying the role of its components in the overall treatment effects.

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