MRI Thermometry Based on Encapsulated Hyperpolarized Xenon

ChemPhysChem ◽  
2010 ◽  
Vol 11 (16) ◽  
pp. 3529-3533 ◽  
Author(s):  
Franz Schilling ◽  
Leif Schröder ◽  
Krishnan K. Palaniappan ◽  
Sina Zapf ◽  
David E. Wemmer ◽  
...  
Keyword(s):  
Hyperpolarized Xenon ◽  
Mri Thermometry

scholarly journals Cover Picture: MRI Thermometry Based on Encapsulated Hyperpolarized Xenon (ChemPhysChem 16/2010)

ChemPhysChem ◽  
2010 ◽  
Vol 11 (16) ◽  
pp. 3369-3369 ◽  
Author(s):  
Franz Schilling ◽  
Leif Schröder ◽  
Krishnan K. Palaniappan ◽  
Sina Zapf ◽  
David E. Wemmer ◽  
...  
Keyword(s):  
Hyperpolarized Xenon ◽  
Mri Thermometry

Coatings for optical pumping cells and extending the lifetime of hyperpolarized xenon

1999 ◽  
Vol 86 (7) ◽  
pp. 4040-4042 ◽  
Author(s):  
Steven R. Breeze ◽  
Stephen Lang ◽  
Igor Moudrakovski ◽  
Chris I. Ratcliffe ◽  
John A. Ripmeester ◽  
...  
Keyword(s):  
Optical Pumping ◽  
Hyperpolarized Xenon

Hyperpolarized Xenon-Based Molecular Sensors for Label-Free Detection of analytes

2013 ◽  
Vol 136 (1) ◽  
pp. 164-168 ◽  
Author(s):  
Praveena D. Garimella ◽  
Tyler Meldrum ◽  
Leah S. Witus ◽  
Monica Smith ◽  
Vikram S. Bajaj ◽  
...  
Keyword(s):  
Label Free ◽  
Molecular Sensors ◽  
Hyperpolarized Xenon ◽  
Label Free Detection

scholarly journals Optimized Continuous Application of Hyperpolarized Xenon to Liquids

2018 ◽  
Vol 122 (48) ◽  
pp. 9359-9369 ◽  
Author(s):  
B. Niederländer ◽  
P. Blümler ◽  
T. Brotin ◽  
D. van Dusschoten ◽  
A. Offenhäusser ◽  
...  
Keyword(s):  
Hyperpolarized Xenon ◽  
Continuous Application

scholarly journals NMR imaging of low pressure, gas-phase transport in packed beds using hyperpolarized xenon-129

AIChE Journal ◽  
2015 ◽  
Vol 61 (11) ◽  
pp. 4013-4019 ◽  
Author(s):  
Galina Pavlovskaya ◽  
Joseph Six ◽  
Thomas Meersman ◽  
Navin Gopinathan ◽  
Sean P. Rigby
Keyword(s):  
Gas Phase ◽  
Low Pressure ◽  
Nmr Imaging ◽  
Packed Beds ◽  
Hyperpolarized Xenon ◽  
Gas Phase Transport ◽  
Phase Transport

Abstract P324: Your Brain May Be "HOTTER" Than You Think, Results From Phase I Check Brain Temperature Study

Stroke ◽  
2021 ◽  
Vol 52 (Suppl_1) ◽  
Author(s):  
David Z Wang ◽  
Jane H Maksimovic ◽  
Maureen L Mathews ◽  
Wen-Ching Liu
Keyword(s):  
Phase I ◽  
Brain Temperature ◽  
Occipital Lobe ◽  
Regions Of Interest ◽  
Tympanic Temperature ◽  
Slice Thickness ◽  
Temperature Study ◽  
Single Voxel ◽  
Mri Thermometry ◽  
Anatomical Images

Background: Hypothermia is a known neuronal protecting agent and used in post cardiac arrest. However, its use for stroke and brain trauma has not made any progress due to the lack of accurate way of measuring brain temperature. Hence, hypothermic degree and duration for it to be therapeutic is unknown. The phase I Check Brain Temperature Study was to define regional brain temperatures in normal individuals via MRI thermometry. The established brain temperature map can be used as the baseline to provide therapeutic hypothermia. Method: Temperatures of 5 regions of interest (ROI) of brain (frontal lobe, thalamus, hypothalamus, occipital lobe and cerebellum) were measured in 10 healthy individuals by using proton resonance frequency MRI spectroscopy single voxel method. The scanning protocol include a whole brain anatomical images, (3DFSPGR : TR/TE=150/3.9ms, FOV=24cm,matrix=256x256, slice thickness =1 mm.) and spectroscopy PRESS (TR/TE=1500/144 ms, 8 nex, 2 x 2 x 2 cm^3) on a GE 3T scanner. Ten right handed men (18<age<80) were recruited and their oral and tympanic temperatures were monitored. Average whole head temperature=average of oral temp+tympanic temp and average brain temp=average of temp of 5 regions of interest. Two tails, paired t-test used to compare temps between subjects and ROIs. Results: Average temperature differences between brain (38.2 °C) and head (36.5 °C) is 1.8 °C (p< 0.0000002). Thalamus has the highest temperature among all ROIs in brain. Brain temperature > oral temperature > tympanic temperature. Conclusion: Brain temperatures may not correlate to body temperatures and there is a regional difference. Our finding will be used as the baseline brain temperature map when hypothermia is applied in patients with hemisphere stroke in the phase II study.

scholarly journals Robust Quantification of Gas Exchange Rates Using Hyperpolarized Xenon-129

2020 ◽  
Author(s):  
F. Amzajerdian ◽  
S. Kadlecek ◽  
H. Hamedani ◽  
Y. Xin ◽  
R. Baron ◽  
...  
Keyword(s):  
Gas Exchange ◽  
Exchange Rates ◽  
Hyperpolarized Xenon

scholarly journals Dissolved hyperpolarized xenon‐129 MRI in human kidneys

2019 ◽  
Vol 83 (1) ◽  
pp. 262-270 ◽  
Author(s):  
Jorge Chacon‐Caldera ◽  
Adam Maunder ◽  
Madhwesha Rao ◽  
Graham Norquay ◽  
Oliver I. Rodgers ◽  
...  
Keyword(s):  
Hyperpolarized Xenon
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