scholarly journals Safety, Pharmacokinetics, and Pharmacodynamics of Trazpiroben (TAK‐906), a Novel Selective D 2 /D 3 Receptor Antagonist: A Phase 1 Randomized, Placebo‐Controlled Single‐ and Multiple‐Dose Escalation Study in Healthy Participants

2021 ◽  
Author(s):  
Roger L. Whiting ◽  
Borje Darpo ◽  
Chunlin Chen ◽  
Margaret Fletcher ◽  
Dan Combs ◽  
...  
Keyword(s):  
Receptor Antagonist ◽  
Dose Escalation ◽  
Multiple Dose ◽  
Phase 1 ◽  
Pharmacokinetics And Pharmacodynamics ◽  
Dose Escalation Study ◽  
Healthy Participants

scholarly journals Inhibition of Complement C3 in Geographic Atrophy with NGM621: Phase 1 Dose-Escalation Study Results

2021 ◽  
Author(s):  
Charles C. Wykoff ◽  
Vrinda Hershberger ◽  
David Eichenbaum ◽  
Erin Henry ◽  
Husam S. Younis ◽  
...  
Keyword(s):  
Dose Escalation ◽  
Phase 1 ◽  
Geographic Atrophy ◽  
Complement C3 ◽  
Dose Escalation Study ◽  
Study Results
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