Pharmacokinetic and Safety Profiles of a Fixed‐Dose Combination of Amlodipine, Valsartan, and Atorvastatin: A 3‐Period Replicate Crossover Study

Seokuee Kim; Jae‐Wook Ko; Jung‐Ryul Kim

doi:10.1002/cpdd.727

Pharmacokinetic and Safety Profiles of a Fixed‐Dose Combination of Amlodipine, Valsartan, and Atorvastatin: A 3‐Period Replicate Crossover Study

Clinical Pharmacology in Drug Development ◽

10.1002/cpdd.727 ◽

2020 ◽

Vol 9 (3) ◽

pp. 386-394

Author(s):

Seokuee Kim ◽

Jae‐Wook Ko ◽

Jung‐Ryul Kim

Keyword(s):

Crossover Study ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Dose Combination

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Comparison of the Pharmacokinetics of Highly Variable Drugs in Healthy Subjects Using a Partial Replicated Crossover Study: A Fixed-Dose Combination of Fimasartan 120 mg and Atorvastatin 40 mg versus Separate Tablets

Drug Design Development and Therapy ◽

10.2147/dddt.s233732 ◽

2020 ◽

Vol Volume 14 ◽

pp. 1953-1961 ◽

Cited By ~ 1

Author(s):

Jungi Hwang ◽

Kyung-Sang Yu ◽

SeungHwan Lee

Keyword(s):

Crossover Study ◽

Healthy Subjects ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Highly Variable Drugs ◽

Dose Combination ◽

Separate Tablets

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A Randomized Crossover Study to Determine Relative Bioequivalence of Tenofovir, Emtricitabine, and Efavirenz (Atripla) Fixed-Dose Combination Tablet Compared With a Compounded Oral Liquid Formulation Derived From the Tablet

JAIDS Journal of Acquired Immune Deficiency Syndromes ◽

10.1097/qai.0b013e31820eefbe ◽

2011 ◽

Vol 56 (5) ◽

pp. e131-e132 ◽

Cited By ~ 11

Author(s):

Jennifer King ◽

Matthew McCall ◽

Anthony Cannella ◽

Michael Anne Markiewicz ◽

Amanda James ◽

...

Keyword(s):

Crossover Study ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Liquid Formulation ◽

Combination Tablet ◽

Oral Liquid ◽

Dose Combination ◽

Randomized Crossover Study

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Pharmacokinetic comparison between fixed-dose combination of fimasartan/amlodipine 60/10 mg and the corresponding loose combination through partial replicated crossover study in healthy subjects

Translational and Clinical Pharmacology ◽

10.12793/tcp.2019.27.4.134 ◽

2019 ◽

Vol 27 (4) ◽

pp. 134

Author(s):

Eunsol Yang ◽

Soyoung Lee ◽

Heechan Lee ◽

Inyoung Hwang ◽

In-Jin Jang ◽

...

Keyword(s):

Crossover Study ◽

Healthy Subjects ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Dose Combination

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Implementation of a Reference-Scaled Average Bioequivalence Approach for Highly Variable Acetylsalicylic Acid in Fixed-Dose Combination with Clopidogrel Versus Enteric Aspirin in Chinese Subjects Under Fasting Conditions: A Phase 1, Open-Label, Randomized, Crossover Study

Advances in Therapy ◽

10.1007/s12325-020-01369-z ◽

2020 ◽

Vol 37 (6) ◽

pp. 2696-2709

Author(s):

Lu Wang ◽

Yujing Di ◽

Tingting Guo ◽

Jeffrey E. Ming ◽

Fangyuan Kong ◽

...

Keyword(s):

Acetylsalicylic Acid ◽

Crossover Study ◽

Phase 1 ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Open Label ◽

Average Bioequivalence ◽

Dose Combination ◽

Randomized Crossover Study ◽

Chinese Subjects

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Bioequivalence of Fixed Dose Combination of Atorvastatin 10 mg and Aspirin 150 mg Capsules: A Randomized, Open-Label, Single-Dose, Two-way Crossover Study in Healthy Human Subjects

Drug Research ◽

10.1055/s-0033-1337931 ◽

2013 ◽

Vol 63 (05) ◽

pp. 250-257 ◽

Cited By ~ 1

Author(s):

S. Tippabhotla ◽

M. Betha ◽

C. Gadiko ◽

R Battula ◽

M. Nakkawar ◽

...

Keyword(s):

Single Dose ◽

Crossover Study ◽

Human Subjects ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Open Label ◽

Healthy Human ◽

Healthy Human Subjects ◽

Dose Combination

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Pharmacokinetics of a telmisartan, amlodipine and hydrochlorothiazide fixed-dose combination: A replicate crossover study in healthy Korean male subjects

Tropical Journal of Pharmaceutical Research ◽

10.4314/tjpr.v16i9.28 ◽

2017 ◽

Vol 16 (9) ◽

pp. 2245 ◽

Cited By ~ 1

Author(s):

Sang Young Lee ◽

Kkot Nim Kang ◽

Jae Hoon Kang ◽

Kyu Ho Jeong ◽

Sang Won Lee ◽

...

Keyword(s):

Crossover Study ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Dose Combination ◽

Male Subjects

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Comparison of the bioavailability and tolerability of fixed-dose combination glimepiride/metformin 2/500-mg tablets versus separate tablets: A single-dose, randomized-sequence, open-label, two-period crossover study in healthy Korean volunteers

Clinical Therapeutics ◽

10.1016/j.clinthera.2010.07.012 ◽

2010 ◽

Vol 32 (7) ◽

pp. 1408-1418 ◽

Cited By ~ 7

Author(s):

Namyi Gu ◽

Bo-Hyung Kim ◽

HyouYoung Rhim ◽

Jae-Yong Chung ◽

Jung-Ryul Kim ◽

...

Keyword(s):

Single Dose ◽

Crossover Study ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Open Label ◽

Dose Combination ◽

Separate Tablets

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Pharmacokinetic Comparison of 2 Fixed-Dose Combination Tablets of Amlodipine and Valsartan in Healthy Male Korean Volunteers: A Randomized, Open-Label, 2-Period, Single-Dose, Crossover Study

Clinical Therapeutics ◽

10.1016/j.clinthera.2013.05.021 ◽

2013 ◽

Vol 35 (7) ◽

pp. 934-940 ◽

Cited By ~ 7

Author(s):

Yukyung Kim ◽

Mijeong Son ◽

Donghwan Lee ◽

Hyerang Roh ◽

Hankil Son ◽

...

Keyword(s):

Single Dose ◽

Crossover Study ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Healthy Male ◽

Open Label ◽

Dose Combination

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A Comparative Pharmacokinetic Study of a Fixed Dose Combination for Essential Hypertensive Patients: A Randomized Crossover Study in Healthy Human Volunteers

Drug Research ◽

10.1055/s-0033-1334882 ◽

2013 ◽

Vol 63 (04) ◽

pp. 177-184 ◽

Cited By ~ 1

Author(s):

B. Gorain ◽

H. Choudhury ◽

D. Halder ◽

A. Sarkar ◽

P. Sarkar ◽

...

Keyword(s):

Crossover Study ◽

Pharmacokinetic Study ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Healthy Human ◽

Comparative Pharmacokinetic ◽

Hypertensive Patients ◽

Human Volunteers ◽

Dose Combination ◽

Randomized Crossover Study

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The Pharmacokinetics and Safety of a Fixed-Dose Combination of Acetylsalicylic Acid and Clopidogrel Compared With the Concurrent Administration of Acetylsalicylic Acid and Clopidogrel in Healthy Subjects: A Randomized, Open-Label, 2-Sequence, 2-Period, Single-Dose Crossover Study

Clinical Therapeutics ◽

10.1016/j.clinthera.2013.05.015 ◽

2013 ◽

Vol 35 (7) ◽

pp. 985-994 ◽

Cited By ~ 8

Author(s):

Jin Ah Jung ◽

Tae-Eun Kim ◽

Jung-Ryul Kim ◽

Min-Ji Kim ◽

Wooseong Huh ◽

...

Keyword(s):

Single Dose ◽

Acetylsalicylic Acid ◽

Crossover Study ◽

Healthy Subjects ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Concurrent Administration ◽

Open Label ◽

Dose Combination

Download Full-text