On Stress in Abdominal Aortic Aneurysm: Linear vs Non‐linear Analysis and Aneurysms Rupture Risk

2021 ◽  
Author(s):  
Adam Wittek ◽  
Farah Alkhatib ◽  
Radek Vitasek ◽  
Stanislav Polzer ◽  
Karol Miller
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Linear Analysis ◽  
Rupture Risk ◽  
Abdominal Aortic ◽  
Non Linear

scholarly journals Grading Abdominal Aortic Aneurysm Rupture Risk

2013 ◽  
Vol 57 (5) ◽  
pp. 43S
Author(s):  
Emiliano Chisci ◽  
Neri Alamanni ◽  
Francesca Iacoponi ◽  
Stefano Michelagnoli ◽  
Setacci Carlo
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Aneurysm Rupture ◽  
Rupture Risk ◽  
Abdominal Aortic Aneurysm Rupture ◽  
Abdominal Aortic

scholarly journals Background and Proposed Design for a Metformin Abdominal Aortic Aneurysm Suppression Trial

2020 ◽  
Vol 3 ◽  
Author(s):  
Ronald L Dalman ◽  
Ying Lu ◽  
Kenneth W Mahaffey ◽  
Amanda J Chase ◽  
Jordan R Stern ◽  
...  
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Controlled Clinical Trial ◽  
Rupture Risk ◽  
Double Blind ◽  
Abdominal Aortic ◽  
Patients With Diabetes ◽  
Risk Patients ◽  
Toxic Potential ◽  
Small Aneurysms

Abdominal aortic aneurysm (AAA) may lead to rupture and death if left untreated. While endovascular or surgical repair is generally recommended for AAA greater than 5–5.5 cm, the vast majority of aneurysms detected by screening modalities are smaller than this threshold. Once discovered, there would be a significant potential benefit in suppressing the growth of these small aneurysms in order to obviate the need for repair and mitigate rupture risk. Patients with diabetes, in particular those taking the oral hypoglycaemic medication metformin, have been shown to have lower incidence, growth rate, and rupture risk of AAA. Metformin therefore represents a widely available, non-toxic, potential inhibitor of AAA growth, but thus far no prospective clinical studies have evaluated this. Here, we present the background, rationale, and design for a randomised, double-blind, placebo-controlled clinical trial of metformin for growth suppression in patients with small AAA.

Model Complexity and Prestressing in Abdominal Aortic Aneurysm Simulation

2009 ◽  
Author(s):  
Michael W. Gee ◽  
Wolfgang A. Wall
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Critical Diameter ◽  
Model Complexity ◽  
Prophylactic Surgery ◽  
Western Society ◽  
Rupture Risk ◽  
Abdominal Aortic ◽  
Precise Prediction ◽  
The Individual

Rupture of abdominal aortic aneurysm (AAA) is the 13th leading cause of death in western society and is fatal in 70–90%. In consequence, precise prediction of AAA rupture risk is essential. With the current, well established CT-morphological parameters such as maximum aortic diameter, aneurysm shape and AAA expansion, only at best the relative, but not the individual rupture risk can be determined. Hence, AAA rupture may occur unexpectedly in small aneurysms below the critical diameter limits whereas many large aneurysms may remain stable throughout patient’s lifetime, without prophylactic surgery.

Estimation of Abdominal Aortic Aneurysm Rupture Risk with Biomechanical Imaging Markers

2019 ◽  
Vol 30 (7) ◽  
pp. 987-994.e4 ◽  
Author(s):  
Hamid Jalalzadeh ◽  
Eva L. Leemans ◽  
Reza Indrakusuma ◽  
R. Nils Planken ◽  
Mark J.W. Koelemay ◽  
...  
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Aneurysm Rupture ◽  
Rupture Risk ◽  
Abdominal Aortic Aneurysm Rupture ◽  
Abdominal Aortic ◽  
Imaging Markers
Sign in / Sign up

Export Citation Format

Share Document