scholarly journals A finite strain nonlinear human mitral valve model with fluid-structure interaction

2014 ◽  
Vol 30 (12) ◽  
pp. 1597-1613 ◽  
Author(s):  
Hao Gao ◽  
Xingshuang Ma ◽  
Nan Qi ◽  
Colin Berry ◽  
Boyce E. Griffith ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Finite Strain ◽  
Fluid Structure Interaction ◽  
Fluid Structure ◽  
Structure Interaction ◽  
Valve Model

scholarly journals Fluid-structure interaction and structural analyses using a comprehensive mitral valve model with 3D chordal structure

2016 ◽  
Vol 33 (4) ◽  
pp. e2815 ◽  
Author(s):  
Milan Toma ◽  
Daniel R. Einstein ◽  
Charles H. Bloodworth ◽  
Richard P. Cochran ◽  
Ajit P. Yoganathan ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Fluid Structure Interaction ◽  
Fluid Structure ◽  
Structure Interaction ◽  
Valve Model

scholarly journals Fluid-Structure Interaction Analysis of Subject-Specific Mitral Valve Regurgitation Treatment with an Intra-Valvular Spacer

Prosthesis ◽  
2020 ◽  
Vol 2 (2) ◽  
pp. 65-75 ◽  
Author(s):  
Milan Toma ◽  
Daniel R. Einstein ◽  
Charles H. Bloodworth ◽  
Keshav Kohli ◽  
Richard P. Cochran ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Mitral Regurgitation ◽  
Interaction Analysis ◽  
Fluid Structure Interaction ◽  
Mitral Valve Regurgitation ◽  
Fluid Structure ◽  
Structure Interaction ◽  
Mitral Regurgitation Severity ◽  
Subject Specific ◽  
Valve Model

Mitral regurgitation imposes a significant symptomatic burden on patients who are not candidates for conventional surgery. For these patients, transcatheter repair and replacement devices are emerging as alternative options. One such device is an intravalvular balloon or spacer that is inserted between the mitral valve leaflets to fill the gap that gives rise to mitral regurgitation. In this study, we apply a large-deformation fluid-structure interaction analysis to a fully 3D subject-specific mitral valve model to assess the efficacy of the intra-valvular spacer for reducing mitral regurgitation severity. The model includes a topologically 3D subvalvular apparatus with unprecedented detail. Results show that device fixation and anchoring at the location of the subject’s regurgitant orifice is imperative for optimal reduction of mitral regurgitation.

scholarly journals Fluid–Structure Interaction Analysis of Papillary Muscle Forces Using a Comprehensive Mitral Valve Model with 3D Chordal Structure

2015 ◽  
Vol 44 (4) ◽  
pp. 942-953 ◽  
Author(s):  
Milan Toma ◽  
Morten Ø. Jensen ◽  
Daniel R. Einstein ◽  
Ajit P. Yoganathan ◽  
Richard P. Cochran ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Papillary Muscle ◽  
Interaction Analysis ◽  
Fluid Structure Interaction ◽  
Muscle Forces ◽  
Fluid Structure ◽  
Structure Interaction ◽  
Valve Model

Fluid-Structure Interaction Simulation of the Edge-to-Edge Repair of the Mitral Valve in Functional and Degenerative States

2012 ◽  
Author(s):  
K. D. Lau ◽  
G. Burriesci ◽  
V. Díaz-Zuccarini
Keyword(s):  
Mitral Valve ◽  
Fluid Structure Interaction ◽  
Mitral Valve Regurgitation ◽  
Fluid Structure ◽  
Explicit Finite Element ◽  
Structure Interaction ◽  
Modelling Techniques ◽  
Induced Stresses ◽  
Annular Dilation ◽  
Ventricular Filling

The most common dysfunction of the mitral valve (MV) is mitral valve regurgitation (MVR) which accounts for approximately 70% of native MV dysfunction [1]. During closure, abnormal amounts of retrograde flow enter the left atrium altering ventricular haemodynamics, an issue which can lead to cardiac related pathologies. MVR is caused by a variety of different mechanisms which are either degenerative (myxomatous degeneration) or functional (annular dilation or papillary muscle displacement) [2]. Correction of MVR is performed by repairing existing valve anatomy or replacement with a prosthetic substitute, however repair is preferred as mortality rates are reduced (2.0% against 6.1% for replacement) along with other valve related complications [3]. A common and popular method of repair is the edge-to-edge repair (ETER), which aims to correct MVR by surgically connecting the regurgitant region through reducing the inter-leaflet distance. Although MV function is improved in systole, induced stresses are significantly increased in diastole where the MV is typically in a low state of stress. In order to assess the effect of this technique in diastole, where the dynamics of both the MV and ventricular filling are disrupted it is required to use fluid-structure interaction (FSI) modelling techniques. Here a FSI model of the of the MV has been described, using this model the resulting induced stresses from the ETER in both functional and degenerative states of the MV have been simulated and assessed using the explicit finite element code LS-DYNA.

Computational Modeling of Aortic Stenosis with a Reduced Degree-Of-Freedom Fluid-Structure Interaction Valve Model

2021 ◽  
Author(s):  
Chi Zhu ◽  
Jung-Hee Seo ◽  
Rajat Mittal
Keyword(s):  
Aortic Stenosis ◽  
Pressure Fluctuations ◽  
Fluid Structure Interaction ◽  
Degree Of Freedom ◽  
Fluid Structure ◽  
Structure Interaction ◽  
Deceleration Phase ◽  
Wall Pressure Fluctuations ◽  
Two Parameters ◽  
Valve Model

Abstract In this study, a novel reduced degree-of-freedom (rDOF) aortic valve model is employed to investigate the fluid-structure interaction and hemodynamics associated with aortic stenosis. The dynamics of the valve leaflets are determined by an ordinary differential equation with two parameters and this rDOF model is shown to reproduce key features of more complex valve models. The hemodynamics associated with aortic stenosis is studied for three cases: a healthy case and two stenosed cases. The focus of the study is to correlate the hemodynamic features with the source generation mechanism of systolic murmurs associated with aortic stenosis. In the healthy case, extremely weak flow fluctuations are observed. However, in the stenosed cases, simulations show significant turbulent fluctuations in the asending aorta, which are responsible for the generation of strong wall pressure fluctuations after the aortic root mostly during the deceleration phase of the systole. The intensity of the murmur generation increases with the severity of the stenosis, and the source locations for the two diseased cases studied here lies around 1.0 inlet duct diameters ($D_o$) downstream of the ascending aorta.

Image-based fluid–structure interaction model of the human mitral valve

2013 ◽  
Vol 71 ◽  
pp. 417-425 ◽  
Author(s):  
Xingshuang Ma ◽  
Hao Gao ◽  
Boyce E. Griffith ◽  
Colin Berry ◽  
Xiaoyu Luo
Keyword(s):  
Mitral Valve ◽  
Fluid Structure Interaction ◽  
Interaction Model ◽  
Fluid Structure ◽  
Structure Interaction

scholarly journals A coupled mitral valve—left ventricle model with fluid–structure interaction

2017 ◽  
Vol 47 ◽  
pp. 128-136 ◽  
Author(s):  
Hao Gao ◽  
Liuyang Feng ◽  
Nan Qi ◽  
Colin Berry ◽  
Boyce E. Griffith ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Left Ventricle ◽  
Fluid Structure Interaction ◽  
Fluid Structure ◽  
Structure Interaction ◽  
Left Ventricle Model
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