Fluid-structure interaction methods in biological flows with special emphasis on heart valve dynamics

2010 ◽  
Vol 26 (3-4) ◽  
pp. 435-470 ◽  
Author(s):  
Sarah C. Vigmostad ◽  
Holavanahalli S. Udaykumar ◽  
Jia Lu ◽  
Krishnan B. Chandran
ASAIO Journal ◽  
2005 ◽  
Vol 51 (2) ◽  
pp. 3A
Author(s):  
Kris Dumont ◽  
Jan Vierendeels ◽  
Patrick Segers ◽  
Guido Van Nooten ◽  
Pascal Verdonck

Fluids ◽  
2019 ◽  
Vol 4 (3) ◽  
pp. 119 ◽  
Author(s):  
Anvar Gilmanov ◽  
Alexander Barker ◽  
Henryk Stolarski ◽  
Fotis Sotiropoulos

When flow-induced forces are altered at the blood vessel, maladaptive remodeling can occur. One reason such remodeling may occur has to do with the abnormal functioning of the aortic heart valve due to disease, calcification, injury, or an improperly-designed prosthetic valve, which restricts the opening of the valve leaflets and drastically alters the hemodynamics in the ascending aorta. While the specifics underlying the fundamental mechanisms leading to changes in heart valve function may differ from one cause to another, one common and important change is in leaflet stiffness and/or mass. Here, we examine the link between valve stiffness and mass and the hemodynamic environment in aorta by coupling magnetic resonance imaging (MRI) with high-resolution fluid–structure interaction (FSI) computational fluid dynamics to simulate blood flow in a patient-specific model. The thoracic aorta and a native aortic valve were re-constructed in the FSI model from the MRI data and used for the simulations. The effect of valve stiffness and mass is parametrically investigated by varying the thickness (h) of the leaflets (h = 0.6, 2, 4 mm). The FSI simulations were designed to investigate systematically progressively higher levels of valve stiffness by increasing valve thickness and quantifying hemodynamic parameters known to be linked to aortopathy and valve disease. The computed results reveal dramatic differences in all hemodynamic parameters: (1) the geometric orifice area (GOA), (2) the maximum velocity V max of the jet passing through the aortic orifice area, (3) the rate of energy dissipation E ˙ diss ( t ) , (4) the total loss of energy E diss , (5) the kinetic energy of the blood flow E kin ( t ) , and (6) the average magnitude of vorticity Ω a ( t ) , illustrating the change in hemodynamics that occur due to the presence of aortic valve stenosis.


Author(s):  
Esfandyar Kouhi ◽  
Yos Morsi

In this paper the fluid structure interaction in stentless aortic heart valve during acceleration phase was performed successfully using the commercial ANSYS/CFX package. The aim is to provide unidirectional coupling FSI analysis of physiological blood flow within an anatomically corrected numerical model of stentless aortic valve. Pulsatile, Newtonian, and turbulent blood flow rheology at aortic level was applied to fluid domain. The proposed structural prosthesis had a novel multi thickness leaflet design decreased from aortic root down to free age surface. An appropriate interpolation scheme used to import the fluid pressure on the structure at their interface. The prosthesis deformations over the acceleration time showed bending dominant characteristic at early stages of the cardiac cycle. More stretching and flattening observed in the rest of the times steps. The multi axial Von Mises stress data analysis was validated with experimental data which confirmed the initial design of the prosthesis.


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