Co‐localization of nociceptive markers in the lumbar dorsal root ganglion and spinal cord of dromedary camel

2021 ◽  
Author(s):  
Hayate Javed ◽  
Sumisha Rehmathulla ◽  
Saeed Tariq ◽  
Mahmoud A. Ali ◽  
Bright Starling Emerald ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Dorsal Root Ganglion ◽  
Dorsal Root ◽  
Dromedary Camel ◽  
Lumbar Dorsal Root Ganglion

scholarly journals Quantitative Sensory Testing of Spinal Cord and Dorsal Root Ganglion Stimulation in Chronic Pain Patients

2021 ◽  
Author(s):  
Vishwanath Sankarasubramanian ◽  
Srinivas Chiravuri ◽  
Ehsan Mirzakhalili ◽  
Carlos J. Anaya ◽  
John Ryan Scott ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Chronic Pain ◽  
Dorsal Root Ganglion ◽  
Dorsal Root ◽  
Quantitative Sensory Testing ◽  
Sensory Testing ◽  
Chronic Pain Patients ◽  
Pain Patients

scholarly journals Phenotypic changes in dorsal root ganglion and spinal cord in the collagen antibody-induced arthritis model

2012 ◽  
Vol 71 (Suppl 1) ◽  
pp. A31.2-A32
Author(s):  
J Su ◽  
T J Shi ◽  
T L Gao ◽  
Z Wiesenfeld-Hallin ◽  
T Hökfelt ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Dorsal Root Ganglion ◽  
Dorsal Root ◽  
Arthritis Model ◽  
Phenotypic Changes

scholarly journals The Team Approach to Spinal Cord and Dorsal Root Ganglion Stimulation: A Guide for the Advanced Practice Provider

2021 ◽  
Author(s):  
Jonathan M. Hagedorn ◽  
Brittney Misercola ◽  
Ashley Comer ◽  
Jeanmarie Tari-Blake ◽  
Chelsey M. Hoffmann ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Dorsal Root Ganglion ◽  
Dorsal Root ◽  
Team Approach ◽  
Advanced Practice

scholarly journals Nuclear Pore Changes and Absence of Apoptosis in Lumbar Dorsal Root Ganglion Neurons of Doxorubicin-Intoxicated Rats

1998 ◽  
Vol 20 (2) ◽  
pp. 115-125
Author(s):  
Man-fu HAN ◽  
Qiu-yue HER ◽  
Akio OHNISHI ◽  
Tatsunori YAMAMOTO ◽  
Hideyuki HASHIGUCHI ◽  
...  
Keyword(s):  
Dorsal Root Ganglion ◽  
Dorsal Root ◽  
Dorsal Root Ganglion Neurons ◽  
Nuclear Pore ◽  
Lumbar Dorsal Root Ganglion ◽  
Ganglion Neurons

scholarly journals Herpes Simplex Viral and Amplicon Vector-Mediated Gene Transfer into Glia and Neurons in Organotypic Spinal Cord and Dorsal Root Ganglion Cultures

2000 ◽  
Vol 1 (5) ◽  
pp. 464-478 ◽  
Author(s):  
Daniel R. Marsh ◽  
Gregory A. Dekaban ◽  
Wei Tan ◽  
Craig A. Strathdee ◽  
Lynne C. Weaver
Keyword(s):  
Spinal Cord ◽  
Herpes Simplex ◽  
Gene Transfer ◽  
Dorsal Root Ganglion ◽  
Dorsal Root

Changes of the neuropeptides content and gene expression in spinal cord and dorsal root ganglion after noxious colorectal distension

2005 ◽  
Vol 131 (1-3) ◽  
pp. 66-73 ◽  
Author(s):  
Ching-Liang Lu ◽  
Pankaj J. Pasricha ◽  
Jen-Chuen Hsieh ◽  
Ray-Hwa Lu ◽  
Chun-Ru Lai ◽  
...  
Keyword(s):  
Gene Expression ◽  
Spinal Cord ◽  
Dorsal Root Ganglion ◽  
Dorsal Root ◽  
Colorectal Distension

Role of Asic3, Nav1.7 and Nav1.8 in Electroacupuncture-Induced Analgesia in a Mouse Model of Fibromyalgia Pain

2018 ◽  
Vol 36 (2) ◽  
pp. 110-116 ◽  
Author(s):  
Liang-Ta Yen ◽  
Yu-Chan Hsu ◽  
Jaung-Geng Lin ◽  
Ching-Liang Hsieh ◽  
Yi-Wen Lin
Keyword(s):  
Spinal Cord ◽  
Side Effects ◽  
Dorsal Root Ganglion ◽  
Mouse Model ◽  
Dorsal Root ◽  
Mechanical Hyperalgesia ◽  
Protein Levels ◽  
The Us ◽  
Preventive Effects

Background The mechanisms underlying fibromyalgia (FM) pain are not understood. The US Food and Drug Administration has recommended three drugs for treating FM—namely, pregabalin, duloxetine and milnacipran; however, these medications are associated with severe side effects. Objective To create a mouse model of FM pain using dual injections of acidic saline to cause mechanical hyperalgesia and test whether ASIC3, Nav1.7 and Nav1.8 are involved in this process and whether electroacupuncture (EA) can reverse these phenomena. Methods The FM model was established by injecting acidic saline twice into 40 ICR mice. The mice were assigned to subgroups (n=8 each) treated with different EA frequencies (2, 15 and 50 Hz). ASIC3, Nav1.7 and Nav1.8 expression levels were measured by Western blotting and immunohistochemistry. Results Significant mechanical hyperalgesia was induced on day 8 in FM mice, which was reversed by 2, 15 and 50 Hz EA. ASIC3, Nav1.7 and Nav1.8 protein levels increased significantly in both the dorsal root ganglion and in the spinal cord of FM model mice. These changes were further attenuated by 2, 15 and 50 Hz EA. Conclusion Reduced nociceptive ASIC3, Nav1.7 and Nav1.8 proteins are involved in the preventive effects of EA against FM, and this series of molecules may represent targets for FM treatment.

Dorsal root ganglion stimulation lead fractures: potential mechanisms and ways to avoid

2021 ◽  
Vol 14 (5) ◽  
pp. e241353
Author(s):  
Gaurav Chauhan ◽  
Brandon I Roth ◽  
Nagy Mekhail
Keyword(s):  
Spinal Cord ◽  
Chronic Pain ◽  
Case Report ◽  
Dorsal Root Ganglion ◽  
Dorsal Root ◽  
Unusual Case ◽  
Pain Syndrome ◽  
Structural Instability ◽  
Probable Mechanism ◽  
Lead Fracture

Dorsal root ganglion stimulation (DRGS) therapy is a rapidly emerging tool being used by pain physicians in the treatment of chronic pain. Complex regional pain syndrome (CRPS), a debilitating disease whose mechanism is still has yet to be fully elucidated, is a common pathology targeted by DRGS therapy, often better results than traditional spinal cord stimulation. DRGS therapy, however, is not bereft of complications. Lead migration and fracture are two examples in particular that are among the most common of these complications. The authors report an unusual case of lost efficacy due to lead fractures in patients with CRPS treated with DRGS. The case report narrates identification, management and probable mechanism of DRGS lead fracture. The structural instability of DRGS leads can yield distressing symptoms at any point during the therapy, and physicians should be cognisant of the complications of DRGS therapy.

Sign in / Sign up

Export Citation Format

Share Document