scholarly journals Axon guidance at the spinal cord midline—A live imaging perspective

2021 ◽  
Author(s):  
Alexandre Dumoulin ◽  
Nikole R. Zuñiga ◽  
Esther T. Stoeckli
Keyword(s):  
Spinal Cord ◽  
Axon Guidance ◽  
Live Imaging ◽  
Imaging Perspective

scholarly journals Dorsal commissural axon guidance in the developing spinal cord

2020 ◽  
Author(s):  
Sandy Alvarez ◽  
Supraja G. Varadarajan ◽  
Samantha J. Butler
Keyword(s):  
Spinal Cord ◽  
Axon Guidance ◽  
Commissural Axon ◽  
Developing Spinal Cord

Axon Guidance in the Spinal Cord

Semaphorins ◽  
2015 ◽  
pp. 39-63
Author(s):  
Fumiyasu Imai ◽  
Yutaka Yoshida
Keyword(s):  
Spinal Cord ◽  
Axon Guidance

Chemorepellent Axon Guidance Molecules in Spinal Cord Injury

2006 ◽  
Vol 23 (3-4) ◽  
pp. 409-421 ◽  
Author(s):  
Simone P. Niclou ◽  
Erich M.E. Ehlert ◽  
Joost Verhaagen
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Axon Guidance ◽  
Cord Injury ◽  
Guidance Molecules

Phenotype of V2-derived interneurons and their relationship to the axon guidance molecule EphA4 in the developing mouse spinal cord

2007 ◽  
Vol 26 (11) ◽  
pp. 2989-3002 ◽  
Author(s):  
Line Lundfald ◽  
C. Ernesto Restrepo ◽  
Simon J. B. Butt ◽  
Chian-Yu Peng ◽  
Steven Droho ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Axon Guidance ◽  
Mouse Spinal Cord ◽  
Axon Guidance Molecule ◽  
Guidance Molecule

scholarly journals Multiple Functions of Draxin/Netrin-1 Signaling in the Development of Neural Circuits in the Spinal Cord and the Brain

2021 ◽  
Vol 15 ◽  
Author(s):  
Giasuddin Ahmed ◽  
Yohei Shinmyo
Keyword(s):  
Spinal Cord ◽  
Axon Guidance ◽  
Neural Circuits ◽  
Neural Circuit ◽  
Deleted In Colorectal Cancer ◽  
Guidance Cue ◽  
Thalamocortical Projections ◽  
The Central Nervous System ◽  
Circuit Formation ◽  
The Brain

Axon guidance proteins play key roles in the formation of neural circuits during development. We previously identified an axon guidance cue, named draxin, that has no homology with other axon guidance proteins. Draxin is essential for the development of various neural circuits including the spinal cord commissure, corpus callosum, and thalamocortical projections. Draxin has been shown to not only control axon guidance through netrin-1 receptors, deleted in colorectal cancer (Dcc), and neogenin (Neo1) but also modulate netrin-1-mediated axon guidance and fasciculation. In this review, we summarize the multifaceted functions of draxin and netrin-1 signaling in neural circuit formation in the central nervous system. Furthermore, because recent studies suggest that the distributions and functions of axon guidance cues are highly regulated by glycoproteins such as Dystroglycan and Heparan sulfate proteoglycans, we discuss a possible function of glycoproteins in draxin/netrin-1-mediated axon guidance.

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