scholarly journals Morphology of visual sector thalamic reticular neurons in the macaque monkey suggests retinotopically specialized, parallel stream-mixed input to the lateral geniculate nucleus

2016 ◽  
Vol 525 (5) ◽  
pp. 1273-1290 ◽  
Author(s):  
Elise M. Bragg ◽  
Elizabeth A. Fairless ◽  
Shiyuan Liu ◽  
Farran Briggs
Keyword(s):  
Lateral Geniculate Nucleus ◽  
Macaque Monkey ◽  
Lateral Geniculate ◽  
Reticular Neurons ◽  
Parallel Stream

Expression of MARCKS mRNA in lateral geniculate nucleus and visual cortex of normal and monocularly deprived macaque monkeys

2002 ◽  
Vol 19 (5) ◽  
pp. 633-643 ◽  
Author(s):  
NORIYUKI HIGO ◽  
TAKAO OISHI ◽  
AKIKO YAMASHITA ◽  
KEIJI MATSUDA ◽  
MOTOHARU HAYASHI
Keyword(s):  
Protein Kinase ◽  
Lateral Geniculate Nucleus ◽  
Macaque Monkey ◽  
Monocular Deprivation ◽  
Major Protein ◽  
Area 17 ◽  
Double Labeling ◽  
Α Subunit ◽  
Kinase Substrate ◽  
Lateral Geniculate

We performed a nonradioactive in situ hybridization histochemistry (ISH) study of the lateral geniculate nucleus (LGN) and the primary visual area (area 17) of the macaque monkey to investigate mRNA expression of the myristoylated alanine-rich C-kinase substrate (MARCKS), a major protein kinase C (PKC) substrate. In the LGN, intense hybridization signals were observed in both magnocellular neurons (layers 1 and 2) and parvocellular neurons (layers 3 to 6). Double labeling using ISH and immunofluorescence revealed that MARCKS mRNA was coexpressed with the α-subunit of type II calcium/calmodulin-dependent protein kinase, indicating that MARCKS mRNA is also expressed in koniocellular neurons in the LGN. GABA-immunoreactive neurons in the LGN did not contain MARCKS mRNA, indicating that MARCKS mRNA is not expressed in inhibitory interneurons. The signals were generally weak in area 17, and intense signals were restricted to large neurons in layers IVB, V, and VI. GABA-immunoreactive neurons in layers II–VI of area 17 did not contain MARCKS mRNA. Double-label ISH revealed that MARCKS mRNA was coexpressed with mRNA of GAP-43, another PKC substrate, in neurons of both the LGN and area 17. To determine whether the expression of MARCKS mRNA is regulated by retinal activity, we performed ISH in the LGN and area 17 of monkeys deprived of monocular visual input by tetrodotoxin. After monocular deprivation for 5 to 30 days, MARCKS mRNA was down-regulated in the LGN, but not in area 17. These results suggest that MARCKS mediates the activity-dependent changes in the excitatory relay neurons in the LGN.

Correlates of motor planning and postsaccadic fixation in the macaque monkey lateral geniculate nucleus

2005 ◽  
Vol 168 (1-2) ◽  
pp. 62-75 ◽  
Author(s):  
D. W. Royal ◽  
Gy. Sáry ◽  
J. D. Schall ◽  
V. A. Casagrande
Keyword(s):  
Lateral Geniculate Nucleus ◽  
Motor Planning ◽  
Macaque Monkey ◽  
Lateral Geniculate

Lagged cells in alert monkey lateral geniculate nucleus

2008 ◽  
Vol 25 (5-6) ◽  
pp. 647-659 ◽  
Author(s):  
ALAN B. SAUL
Keyword(s):  
Lateral Geniculate Nucleus ◽  
Extracellular Recording ◽  
Macaque Monkey ◽  
Direction Selectivity ◽  
Alert Monkey ◽  
Lateral Geniculate ◽  
Multiple Dimensions ◽  
Wide Range ◽  
Lagged Cells ◽  
Response Timing

AbstractFive lagged cells were recognized by extracellular recording in the lateral geniculate nucleus of an awake, behaving macaque monkey. Previous reports of lagged cells were all in the anesthetized cat. Both parvocellular and magnocellular lagged cells were observed. Response timing was distributed continuously across the population, and both sustained and transient responses were seen in the magnocellular subpopulation. Cortex thus receives signals with a wide range of timing, which can mediate direction selectivity across multiple dimensions.

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