Role of plasma membrane estrogen receptors in mediating the estrogen induction of progesterone receptors in hypothalamic ventromedial neurons

2013 ◽  
Vol 522 (2) ◽  
pp. 298-307 ◽  
Author(s):  
Susana I. Sá ◽  
Pedro A. Pereira ◽  
Viacheslav Malikov ◽  
Isabel M.P.L.V.O. Ferreira ◽  
M. Dulce Madeira
Keyword(s):  
Plasma Membrane ◽  
Estrogen Receptors ◽  
Progesterone Receptors ◽  
Estrogen Induction

scholarly journals Endometriosis disease: the patogenetic role of hormone resepters and methods of diagnosis

2018 ◽  
Vol 96 (9) ◽  
pp. 796-803
Author(s):  
Anna O. Drobintseva ◽  
A. E. Andreev ◽  
V. O. Polyakova ◽  
I. M. Kvetnoy
Keyword(s):  
Progesterone Receptor ◽  
Estrogen Receptors ◽  
Hormone Receptor ◽  
Normal Tissue ◽  
Hormone Receptors ◽  
Progesterone Receptors ◽  
Data Sources ◽  
Prolactin Receptors ◽  
Melatonin Receptor

This review summarizes current literature data taken from the information bases of elibrary and pubmed, on hormone receptors, which participate or have a significant impact on the pathogenesis of endometrial disease according to new data sources. They include estrogen receptors (ERa; ERe), progesterone receptors (PRA; PRB), prolactin receptors (PLR), anti-mullerian hormone receptor (AMHR2), kisspeptin receptor (KISS1R) and melatonin receptor (MR). It was established that expression of ERe genes is up-regulated in heterotopy, whereas ERa expression is lower compared to normal tissue. The progesterone receptor is of great interest for study because of inconsistent data on its expression. Receptors for anti-mullerian hormone hormone is no less significant in the study of the pathogenesis of the disease, since AMH stimulates apoptosis in endometrioid cells, limiting their expansion. The most controversial role in endometriosis belongs to prolactin receptors, some authors believe that in endometriosis, a decrease in expression of PLR is observed, while in other articles an increase of expression is postulated. It has been shown that in patients with endometriosis, the expression of the KISS1R is reduced in the endometrium. The data on the expression of melatonin and its receptors in endometriosis is absence.

Role of Exosomes in the Exchange of Spermatozoa after Leaving the Seminiferous Tubule: A Review

2020 ◽  
Vol 21 (5) ◽  
pp. 330-338
Author(s):  
Luming Wu ◽  
Yuan Ding ◽  
Shiqiang Han ◽  
Yiqing Wang
Keyword(s):  
Drug Delivery ◽  
Plasma Membrane ◽  
Seminiferous Tubule ◽  
Metabolic Diseases ◽  
Inflammatory Diseases ◽  
Multivesicular Bodies ◽  
Extensive Search ◽  
Neurological Research ◽  
The One

Background: Exosomes are extracellular vesicles (EVs) released from cells upon fusion of an intermediate endocytic compartment with the plasma membrane. They refer to the intraluminal vesicles released from the fusion of multivesicular bodies with the plasma membrane. The contents and number of exosomes are related to diseases such as metabolic diseases, cancer and inflammatory diseases. Exosomes have been used in neurological research as a drug delivery tool and also as biomarkers for diseases. Recently, exosomes were observed in the seminal plasma of the one who is asthenozoospermia, which can affect sperm motility and capacitation. Objective: The main objective of this review is to deeply discuss the role of exosomes in spermatozoa after leaving the seminiferous tubule. Methods: We conducted an extensive search of the literature available on relationships between exosomes and exosomes in spermatozoa on the bibliographic database. Conclusion: : This review thoroughly discussed the role that exosomes play in the exchange of spermatozoa after leaving the seminiferous tubule and its potential as a drug delivery tool and biomarkers for diseases as well.

The role of plasmalogens, Forssman lipids, and sphingolipid hydroxylation in modulating the biophysical properties of the epithelial plasma membrane

2021 ◽  
Vol 154 (9) ◽  
pp. 095101
Author(s):  
Katie A. Wilson ◽  
Stephen J. Fairweather ◽  
Hugo I. MacDermott-Opeskin ◽  
Lily Wang ◽  
Richard A. Morris ◽  
...  
Keyword(s):  
Plasma Membrane ◽  
Biophysical Properties
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