Low-level laser therapy alleviates neuropathic pain and promotes function recovery in rats with chronic constriction injury: Possible involvements in hypoxia-inducible factor 1α (HIF-1α)

2012 ◽  
Vol 520 (13) ◽  
pp. 2903-2916 ◽  
Author(s):  
Yueh-Ling Hsieh ◽  
Li-Wei Chou ◽  
Pei-Lin Chang ◽  
Chen-Chia Yang ◽  
Mu-Jung Kao ◽  
...  
2013 ◽  
Vol 1 (2) ◽  
pp. 76-81 ◽  
Author(s):  
Masoume Masoumipoor ◽  
Seyed Behnam Jameie ◽  
Atusa Janzadeh ◽  
Farinaz Nasirinezhad ◽  
Mahdie Kerdari ◽  
...  

Author(s):  
Ana Laura Martins de Andrade ◽  
Paulo Ségio Bossini ◽  
Nivaldo Antônio Parizotto

Hypertension ◽  
2014 ◽  
Vol 64 (suppl_1) ◽  
Author(s):  
Jose A Silva ◽  
Regiane S Feliciano ◽  
Andrey J Serra ◽  
Martha T Manchini ◽  
Eduardo T Santana ◽  
...  

Low-level laser therapy (LLLT) has been used as an anti-inflammatory alternative treatment in several disease conditions, even when inflammation is a secondary consequence, such as in myocardial infarction (MI). LLLT treatment effectively reduces MI size and attenuates the systolic dysfunction after MI. However, the mechanism by which LLLT is able to protect the remaining myocardium remains unclear. Here, we tested the hypothesis that LLLT might reduce the hypoxia effects generated by MI. To achieve this purpose, we evaluated, after laser irradiation, the modulation of hypoxia-inducible factor (HIF) and microRNA 210 expressions, which are consistently stimulated under hypoxic conditions. We observed that HIF content presented an up-regulation after MI, however, a significant augmented HIF expression was observed after LLLT. Accordingly, micro-RNA 210 expression in the MI remote area increased even further after laser irradiation. Our data suggest that LLLT stimulates HIF expression pathway, increasing hypoxia-induced microRNA 210 content after MI, therefore, highlighting a possible cardioprotective role of LLLT.


Author(s):  
VARSHA PALLED ◽  
DR. JITENDRA RAO ◽  
DR. RAGHUWAR DAYAL SINGH ◽  
DR. SHUCHI TRIPATHI ◽  
DR. KALPANA SINGH ◽  
...  

The purpose of this study was to evaluate whether Low-Level Laser Therapy (LLLT) improves the healing of the implant surgical site with clinical and biochemical parameters.Thirty patients with an edentulous space spanning a single tooth were selected. The patients were randomly allocated to two groups - the control group and the test group. The test group received laser energy at a power of 2J/cm 2 with a total of 4-6J energy over each implant. Clinical parameters (Implant Stability Quotient, probing index, modified sulcus bleeding index)and osteoprotegerin (OPG) were assessed at baseline and follow-up intervals (2 weeks, 6 weeks, and 3 months).The test group showed significantly higher implant stability quotient compared to thecontrol group at 2 weeks(57.93±3.95 and 35.67±3.08; p<0.01) and 3months(58.86±3.75 and 67.06±3.78; p<0.01). A significant rise in OPG levels of the test group(686.30±125.36pg/ml at baseline and 784.25±108.30pg/ml at 3months;p<0.01) was seen contrary to significant decline in the control group (839.50±249.08pg/ml at baseline,415.30±78.39pg/ml at 3months;p<0.01). Within the limitations of the study, the study suggests that the healing of peri-implant hard and soft tissues may be enhanced with the use of LLLT as an explicit modality during the post-operative period.


2020 ◽  
Vol 69 (3) ◽  
Author(s):  
Paulo Esteves Pinto Faria ◽  
Astrid Temprano ◽  
Fábio Piva ◽  
Eduardo Sant'ana ◽  
Dênis Pimenta

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