scholarly journals Corticotropin-releasing factor binding protein within the ventral tegmental area is expressed in a subset of dopaminergic neurons

2008 ◽  
Vol 509 (3) ◽  
pp. 302-318 ◽  
Author(s):  
Hui-Ling Wang ◽  
Marisela Morales
Keyword(s):  
Ventral Tegmental Area ◽  
Dopaminergic Neurons ◽  
Binding Protein ◽  
Corticotropin Releasing Factor ◽  
Factor Binding ◽  
Ventral Tegmental

scholarly journals Smoke Extracts and Nicotine, but not Tobacco Extracts, Potentiate Firing and Burst Activity of Ventral Tegmental Area Dopaminergic Neurons in Mice

2011 ◽  
Vol 36 (11) ◽  
pp. 2244-2257 ◽  
Author(s):  
Fabio Marti ◽  
Ouafa Arib ◽  
Carole Morel ◽  
Virginie Dufresne ◽  
Uwe Maskos ◽  
...  
Keyword(s):  
Ventral Tegmental Area ◽  
Dopaminergic Neurons ◽  
Burst Activity ◽  
Ventral Tegmental

Methylphenidate and amphetamine modulate differently the NMDA and AMPA glutamatergic transmission of dopaminergic neurons in the ventral tegmental area

Life Sciences ◽  
2005 ◽  
Vol 77 (6) ◽  
pp. 635-649 ◽  
Author(s):  
B. Prieto-Gómez ◽  
A.M. Vázquez-Alvarez ◽  
J.L. Martínez-Peña ◽  
C. Reyes-Vázquez ◽  
P.B. Yang ◽  
...  
Keyword(s):  
Ventral Tegmental Area ◽  
Dopaminergic Neurons ◽  
Glutamatergic Transmission ◽  
Ventral Tegmental

Cardiovascular depressor responses to stimulation of substantia nigra and ventral tegmental area

1997 ◽  
Vol 273 (6) ◽  
pp. H2549-H2557 ◽  
Author(s):  
Gilbert J. Kirouac ◽  
John Ciriello
Keyword(s):  
Substantia Nigra ◽  
Ventral Tegmental Area ◽  
Intravenous Administration ◽  
Dopaminergic Neurons ◽  
Cardiovascular Responses ◽  
Receptor Blocker ◽  
Transitional Region ◽  
Pars Lateralis ◽  
Ventral Tegmental ◽  
Stimulation Of

Experiments were done in α-chloralose-anesthetized, paralyzed, and artificially ventilated rats to investigate the effect ofl-glutamate (Glu) stimulation of the substantia nigra (SN) and ventral tegmental area (VTA) on arterial pressure (AP) and heart rate (HR). Glu stimulation of the SN pars compacta (SNC) elicited decreases in both mean AP (MAP; −18.9 ± 1.3 mmHg; n = 52) and HR (−26.1 ± 1.6 beats/min; n = 46) at 81% of the sites stimulated. On the other hand, stimulation of the SN pars lateralis or pars reticulata did not elicit cardiovascular responses. Stimulation of the adjacent VTA region elicited similar decreases in MAP (−18.0 ± 2.6 mmHg; n = 20) and HR (−25.4 ± 3.8 beats/min; n = 17) at ∼74% of the sites stimulated. Intravenous administration of the dopamine D2-receptor antagonist raclopride significantly attenuated both the MAP (70%) and the HR (54%) responses elicited by stimulation of the transitional region where the SNC merges with the lateral VTA (SNC-VTA region). Intravenous administration of the muscarinic receptor blocker atropine methyl bromide had no effect on the magnitude of the MAP and HR responses to stimulation of the SNC-VTA region, whereas administration of the nicotinic receptor blocker hexamethonium bromide significantly attenuated both the depressor and the bradycardic responses. These data suggest that dopaminergic neurons in the SNC-VTA region activate a central pathway that exerts cardiovascular depressor effects that are mediated by the inhibition of sympathetic vasoconstrictor fibers to the vasculature and cardioacceleratory fibers to the heart.

scholarly journals Otx2 expression is restricted to dopaminergic neurons of the ventral tegmental area in the adult brain

2010 ◽  
Vol 54 (5) ◽  
pp. 939-945 ◽  
Author(s):  
Michela Di Salvio ◽  
Luca G. Di Giovannantonio ◽  
Daniela Omodei ◽  
Dario Acampora ◽  
Antonio Simeone
Keyword(s):  
Ventral Tegmental Area ◽  
Dopaminergic Neurons ◽  
Adult Brain ◽  
Ventral Tegmental
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