Coexpression of vesicular glutamate transporter-3 and γ-aminobutyric acidergic markers in rat rostral medullary raphe and intermediolateral cell column

2005 ◽  
Vol 492 (4) ◽  
pp. 477-494 ◽  
Author(s):  
Ruth L. Stornetta ◽  
Diane L. Rosin ◽  
Johnny R. Simmons ◽  
Travis J. McQuiston ◽  
Nina Vujovic ◽  
...  
Keyword(s):  
Glutamate Transporter ◽  
Vesicular Glutamate Transporter ◽  
Cell Column ◽  
Medullary Raphe

scholarly journals Activity-Dependent Modulation of Neurotransmitter Innervation to Vasopressin Neurons of the Supraoptic Nucleus

Endocrinology ◽  
2005 ◽  
Vol 146 (1) ◽  
pp. 348-354 ◽  
Author(s):  
Nancy K. Mueller ◽  
Shi Di ◽  
Charles M. Paden ◽  
James P. Herman
Keyword(s):  
Glutamic Acid ◽  
Glutamic Acid Decarboxylase ◽  
Supraoptic Nucleus ◽  
Glutamate Transporter ◽  
Acid Decarboxylase ◽  
Vesicular Glutamate Transporter ◽  
Salt Loading ◽  
Synaptic Boutons ◽  
Vasopressin Neurons ◽  
Activity Dependent

Confocal microscopy was used to assess activity-dependent neuroplasticity in neurotransmitter innervation of vasopressin immunoreactive magnocellular neurons in the supraoptic nucleus (SON). Vesicular glutamate transporter 2, glutamic acid decarboxylase, and dopamine β-hydroxylase (DBH) synaptic boutons were visualized in apposition to vasopressin neurons in the SON. A decrease in DBH synaptic boutons per cell was seen upon salt loading, indicating diminished noradrenergic/adrenergic innervation. Loss of DBH appositions to vasopressin neurons was associated with a general loss of DBH immunoreactivity in the SON. In contrast, the number of vesicular glutamate transporter 2 synaptic boutons per neuron increased with salt loading, consistent with increased glutamatergic drive of magnocellular SON neurons. Salt loading also caused an increase in the total number of glutamic acid decarboxylase synaptic boutons on vasopressinergic neurons, suggesting enhanced inhibitory innervation as well. These studies indicate that synaptic plasticity compensates for increased secretory demand and may indeed underlie increased secretion, perhaps via neurotransmitter-specific, activity-related changes in synaptic contacts on vasopressinergic magnocellular neurons in the SON.

Vesicular Glutamate Transporter 2 (VGLUT2) on GnRH Secretory Vesicles

2011 ◽  
pp. P2-265-P2-265
Author(s):  
Weiling Yin ◽  
Zongrong Sun ◽  
Deena M Walker ◽  
Penny D Riha ◽  
John M Mendenhall ◽  
...  
Keyword(s):  
Glutamate Transporter ◽  
Secretory Vesicles ◽  
Vesicular Glutamate Transporter

scholarly journals The vesicular glutamate transporter VGLUT3 contributes to protection against neonatal hypoxic stress

2012 ◽  
Vol 590 (20) ◽  
pp. 5183-5198 ◽  
Author(s):  
Stéphanie Miot ◽  
Nicolas Voituron ◽  
Adélaïde Sterlin ◽  
Erika Vigneault ◽  
Lydie Morel ◽  
...  
Keyword(s):  
Glutamate Transporter ◽  
Hypoxic Stress ◽  
Vesicular Glutamate Transporter
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