Dopamine D5 receptor localization on cholinergic neurons of the rat forebrain and diencephalon: A potential neuroanatomical substrate involved in mediating dopaminergic influences on acetylcholine release

2005 ◽  
Vol 492 (1) ◽  
pp. 34-49 ◽  
Author(s):  
Monica Lisa Berlanga ◽  
Taylor Kathryn Simpson ◽  
Adriana Angelica Alcantara
Keyword(s):  
Acetylcholine Release ◽  
Cholinergic Neurons ◽  
Receptor Localization ◽  
Rat Forebrain ◽  
Dopamine D5 Receptor

Relationships between Acetylcholine Release and Membrane Phosphatidylcholine Turnover in Brain and in Cultured Cholinergic Neurons

1986 ◽  
pp. 283-290 ◽  
Author(s):  
Jan Krzysztof Blusztajn ◽  
Pamela G. Holbrook ◽  
Michael Lakher ◽  
Mordechai Liscovitch ◽  
Jean-Claude Maire ◽  
...  
Keyword(s):  
Acetylcholine Release ◽  
Cholinergic Neurons

Vasoactive intestinal polypeptide provokes acetylcholine release from the myenteric plexus

1986 ◽  
Vol 251 (1) ◽  
pp. G51-G55 ◽  
Author(s):  
M. Kusunoki ◽  
L. H. Tsai ◽  
K. Taniyama ◽  
C. Tanaka
Keyword(s):  
Vasoactive Intestinal Polypeptide ◽  
Myenteric Plexus ◽  
Acetylcholine Release ◽  
Longitudinal Muscle ◽  
Cholinergic Neurons ◽  
Ach Release ◽  
Perfusion Medium ◽  
Release Of Acetylcholine ◽  
Stimulation Of ◽  
Intestinal Polypeptide

Effects of vasoactive intestinal polypeptide (VIP) on the release of acetylcholine (ACh) from longitudinal muscle strips with myenteric plexus (LM) preparations were examined in the guinea pig small intestine. VIP (10(-10) to 10(-6) M) induced a concentration-dependent contraction of LM preparation. The VIP-induced contractions seem to be related to three components, the scopolamine-sensitive, the scopolamine-insensitive, the tetrodotoxin-sensitive, and the tetrodotoxin-insensitive contractions. VIP (10(-10) to 10(-6) M) induced a concentration-dependent increase in the release of [3H]ACh from LM preparations preloaded with [3H]choline. The VIP-evoked [3H]ACh release was inhibited by removal of Ca2+ from the perfusion medium and by treatment with tetrodotoxin but not by scopolamine and hexamethonium. The spontaneous and VIP-evoked [3H]ACh release was not affected by phentolamine, propranolol, methysergide, diphenhydramine, cimetidine, bicuculline, or [D-Pro2, D-Trp7,9]substance P. The result demonstrates that VIP induces contractions of longitudinal smooth muscle directly and indirectly by the stimulation of both cholinergic neurons and noncholinergic excitatory neurons.

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