scholarly journals Effects of functional group position on spatial representations of aliphatic odorants in the rat olfactory bulb

2005 ◽  
Vol 483 (2) ◽  
pp. 192-204 ◽  
Author(s):  
Brett A. Johnson ◽  
Haleh Farahbod ◽  
Sepideh Saber ◽  
Michael Leon
Keyword(s):  
Olfactory Bulb ◽  
Functional Group ◽  
Spatial Representations ◽  
Group Position

Effect of functional group position change of pyridinesulfonic acid as interface-modified layer on perovskite solar cell

2018 ◽  
Vol 462 ◽  
pp. 517-525 ◽  
Author(s):  
Fei Han ◽  
Zeyi Tu ◽  
Zhongquan Wan ◽  
Junsheng Luo ◽  
Jianxing Xia ◽  
...  
Keyword(s):  
Solar Cell ◽  
Functional Group ◽  
Perovskite Solar Cell ◽  
Position Change ◽  
Group Position ◽  
Modified Layer

Computational electrochemistry study of derivatives of anthraquinone and phenanthraquinone analogues: the substitution effect

RSC Advances ◽  
2016 ◽  
Vol 6 (92) ◽  
pp. 89827-89835 ◽  
Author(s):  
Zhen Wang ◽  
Anyang Li ◽  
Lei Gou ◽  
Jingzheng Ren ◽  
Gaohong Zhai
Keyword(s):  
Redox Potential ◽  
Functional Group ◽  
Substitution Effect ◽  
Single Electron ◽  
Group Position ◽  
Computational Electrochemistry ◽  
Electron Withdrawing Group ◽  
Derivatives Of

Effects of functional group position on the calculated redox potential for the single electron-withdrawing group substitution of phenanthraquinone analogues.

scholarly journals The Effect of Functional Group Position of the Piperidine Derivatives on the CO2Absorption Characteristics in the (H2O-Piperidine-CO2) System

2015 ◽  
Vol 53 (1) ◽  
pp. 57-63 ◽  
Author(s):  
Jeong Ho Choi ◽  
Soung Hee Yun ◽  
Yeong Eun Kim ◽  
Yeo Il Yoon ◽  
Sung Chan Nam
Keyword(s):  
Functional Group ◽  
Group Position

Coding of odor molecules by mitral/tufted cells in rabbit olfactory bulb. I. Aliphatic compounds

1992 ◽  
Vol 68 (6) ◽  
pp. 1986-2002 ◽  
Author(s):  
K. Imamura ◽  
N. Mataga ◽  
K. Mori
Keyword(s):  
Fatty Acids ◽  
Olfactory Bulb ◽  
Functional Group ◽  
Hydrocarbon Chain ◽  
Main Olfactory Bulb ◽  
Aliphatic Aldehydes ◽  
Aliphatic Compounds ◽  
Hydrocarbon Chains ◽  
Tufted Cells ◽  
Chain Lengths

1. Recordings of extracellular spike responses were made from single mitral/tufted cells in the main olfactory bulb of urethan-anesthetized rabbits. Olfactory epithelium ipsilateral to the recorded olfactory bulb was stimulated with homologous series of aliphatic compounds using periodic artificial inhalations. 2. In the dorsomedial part of the main olfactory bulb, single mitral/tufted cells were activated by subsets of n-fatty acids with similar hydrocarbon chain lengths. Response selectivities of single mitral/tufted cells were examined in detail using a series of n-fatty acids at five different concentrations. The results indicate that although the range of effective fatty acids is broader at the higher concentrations, the best response at higher concentrations was similar to that determined at lower concentrations. 3. Analysis of single-unit responses to the panel of fatty acids, including those with branched hydrocarbon chains, suggested that the determinants for the response specificities of individual mitral/tufted cells in the dorsomedial region include the overall size of hydrocarbon chains of the odor ligand molecules. 4. Single mitral/tufted cells in the dorsomedial region tended to be activated not only by fatty acids but also by n-aliphatic aldehydes. For a panel of a homologous series of n-aldehydes at five different concentrations, individual mitral/tufted cells showed response selectivity to subsets of aldehydes with similar hydrocarbon chain lengths. 5. In most cases, normal aliphatic alcohols and alkanes were ineffective in activating mitral/tufted cells in the dorsomedial region. This suggests that carbonyl group (--C = O) in the odor molecules plays an important role in determining response specificity of these neurons. 6. Examination with an expanded panel of stimulus odor molecules that included ketones and esters indicated that single mitral/tufted cells sensitive to subsets of fatty acids and n-aliphatic aldehydes were also responsive to subsets of ketones and/or esters having hydrocarbon chain lengths similar to those of the effective fatty acids and aldehydes. 7. The present results show a clear correlation between the tuning specificity of individual mitral/tufted cells and the stereochemical structure of the odor molecules, with respect to 1) length and/or structure of hydrocarbon chain, 2) difference in functional group, and 3) position of the functional group within the molecule. 8. A hypothetical diagram suggesting functional convergence of olfactory nerve input to individual glomeruli is proposed to explain the mechanism for selective activation of individual mitral/tufted cells by a range of odor molecules with similar stereochemical structures.

Spatial Representation of Hydrocarbon Odorants in the Ventrolateral Zones of the Rat Olfactory Bulb

2005 ◽  
Vol 93 (2) ◽  
pp. 1007-1019 ◽  
Author(s):  
Kei M. Igarashi ◽  
Kensaku Mori
Keyword(s):  
Olfactory Bulb ◽  
Functional Groups ◽  
Spatial Representation ◽  
Functional Group ◽  
Odorant Receptor ◽  
Systematic Difference ◽  
Intrinsic Signal ◽  
Molecular Features ◽  
The Common ◽  
Polar Functional Groups

The glomerular sheet of the olfactory bulb (OB) forms odorant receptor maps that are parceled into zones. We previously reported the molecular receptive range (MRR) property of individual glomeruli in the dorsal zone (zone 1) of the OB and showed that polar functional groups play a major role in activating glomeruli in this zone. However, the MRR property of glomeruli in zones 2–4 is not well understood yet. Using the method of intrinsic signal imaging, we recorded odorant-induced glomerular activity from the ventrolateral surface (zones 2–4) of rat OB. While hydrocarbon odorants that lack polar functional groups activate only a few glomeruli in zone 1, we found that a series of hydrocarbon odorants consistently activated many glomeruli in the ventrolateral surface. The hydrocarbon-responsive glomeruli were grouped into two clusters; glomeruli in one cluster (cluster H) responded to benzene-family hydrocarbons but not to cyclic terpene hydrocarbons. Glomeruli in the other cluster (cluster I) responded to both classes of hydrocarbons. Detailed analyses of MRR properties of individual glomeruli using hydrocarbon odorants and polar-functional-group-containing odorants showed that the common and characteristic molecular features effective in activating glomeruli in the clusters H and I are the hydrocarbon skeleton. These results suggest that ORs represented by glomeruli in these clusters recognize primarily the hydrocarbon skeleton of odorants, and thus imply a systematic difference in the manner of recognizing odorant molecular features between ORs in zone 1 and ORs in zones 2–4.

scholarly journals Effects of double and triple bonds on the spatial representations of odorants in the rat olfactory bulb

2006 ◽  
Vol 500 (4) ◽  
pp. 720-733 ◽  
Author(s):  
Brett A. Johnson ◽  
Joan Ong ◽  
Kaman Lee ◽  
Sabrina L. Ho ◽  
Spart Arguello ◽  
...  
Keyword(s):  
Olfactory Bulb ◽  
Spatial Representations ◽  
Triple Bonds
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