Differential expression of Eph receptors and ephrins in the cochlear ganglion and eighth cranial nerve of the chick embryo

2005 ◽  
Vol 482 (4) ◽  
pp. 309-319 ◽  
Author(s):  
Shazia A. Siddiqui ◽  
Karina S. Cramer
Keyword(s):  
Chick Embryo ◽  
Differential Expression ◽  
Cranial Nerve ◽  
Eph Receptors ◽  
Eighth Cranial Nerve

scholarly journals Vestibular neuritis caused by severe acute respiratory syndrome coronavirus 2 infection diagnosed by serology: Case report

2021 ◽  
Vol 9 ◽  
pp. 2050313X2110132
Author(s):  
Alexandra Halalau ◽  
Madalina Halalau ◽  
Christopher Carpenter ◽  
Amr E Abbas ◽  
Matthew Sims
Keyword(s):  
Case Report ◽  
Severe Acute Respiratory Syndrome ◽  
Medical History ◽  
Cranial Nerve ◽  
Respiratory Illness ◽  
Vestibular Neuritis ◽  
Past Medical History ◽  
Significant Past Medical History ◽  
Eighth Cranial Nerve ◽  
Male Physician

Vestibular neuritis is a disorder selectively affecting the vestibular portion of the eighth cranial nerve generally considered to be inflammatory in nature. There have been no reports of severe acute respiratory syndrome coronavirus 2 causing vestibular neuritis. We present the case of a 42-year-old Caucasian male physician, providing care to COVID-19 patients, with no significant past medical history, who developed acute vestibular neuritis, 2 weeks following a mild respiratory illness, later diagnosed as COVID-19. Physicians should keep severe acute respiratory syndrome coronavirus 2 high on the list as a possible etiology when suspecting vestibular neuritis, given the extent and implications of the current pandemic and the high contagiousness potential.

Malignant peripheral nerve sheath tumors of the eighth cranial nerve arising without prior irradiation

2016 ◽  
Vol 125 (5) ◽  
pp. 1120-1129 ◽  
Author(s):  
Matthew L. Carlson ◽  
Jeffrey T. Jacob ◽  
Elizabeth B. Habermann ◽  
Amy E. Glasgow ◽  
Aditya Raghunathan ◽  
...  
Keyword(s):  
Systematic Review ◽  
Peripheral Nerve ◽  
Cranial Nerve ◽  
English Literature ◽  
Seer Database ◽  
Eighth Cranial Nerve ◽  
Nerve Sheath Tumors ◽  
Peripheral Nerve Sheath Tumors ◽  
Nerve Sheath

OBJECTIVE Malignant peripheral nerve sheath tumors (MPNSTs) of the eighth cranial nerve (CN) are exceedingly rare. To date the literature has focused on MPNSTs occurring after radiation therapy for presumed benign vestibular schwannomas (VSs), while MPNSTs arising without prior irradiation have received little attention. The objectives of the current study are to characterize the epidemiology, clinical presentation, disease course, and outcome using a large national cancer registry database and a systematic review of the English literature. Additionally, a previously unreported case is presented. METHODS The authors conducted an analysis of the Surveillance, Epidemiology, and End Results (SEER) database, a systematic review of the literature, and present a case report. Data from all patients identified in the SEER database with a diagnosis of MPNST involving the eighth CN, without a history of prior radiation, were analyzed. Additionally, all cases reported in the English literature between January 1980 and March 2015 were reviewed. Finally, 1 previously unreported case is presented. RESULTS The SEER registries identified 30 cases between 1992 and 2012. The average incidence was 0.017 per 1 million persons per year (range 0.000–0.0687 per year). The median age at diagnosis was 55 years, and 16 (53%) were women. Thirteen cases were diagnosed upon autopsy. Of the 17 cases diagnosed while alive, the median follow-up was 118 days, with 3 deaths (18%) observed. When compared with the incidence of benign VS, 1041 VSs present for every 1 MPNST arising from the eighth CN. Including a previously unreported case from the authors' center, a systematic review of the English literature yielded 24 reports. The median age at diagnosis was 44 years, 50% were women, and the median tumor size at diagnosis was 3 cm. Eleven patients (46%) reported isolated audiovestibular complaints typical for VS while 13 (54%) exhibited facial paresis or other signs of a more aggressive process. Treatment included microsurgery alone, microsurgery with adjuvant radiation, or microsurgery with chemoradiation. Sixty-one percent of patients receiving treatment experienced recurrence, 22% of which were diagnosed with drop metastases to the spine. Ultimately, 13 patients (54%) died of progressive disease at a median of 3 months following diagnosis. The ability to achieve gross-total resection was the only feature that was associated with improved disease-specific survival. CONCLUSIONS MPNSTs of the eighth CN are extremely rare and portend a poor prognosis. Nearly half of patients initially present with findings consistent with a benign VS, often making an early diagnosis challenging. In light of these data, early radiological and clinical follow-up should be considered in those who elect nonoperative treatment, particularly in patients with a short duration of symptoms or atypical presentation. These data also provide a baseline rate of malignancy that should be considered when estimating the risk of malignant transformation following stereotactic radiosurgery for VS.

Benign nasal schwannoma

1992 ◽  
Vol 106 (11) ◽  
pp. 1011-1015 ◽  
Author(s):  
Martin J. Donnelly ◽  
Mohammed Hussain Al-Sader ◽  
Alexander W. Blayney
Keyword(s):  
Head And Neck ◽  
Current Literature ◽  
Paranasal Sinuses ◽  
Cranial Nerve ◽  
Neck Region ◽  
Case Review ◽  
Eighth Cranial Nerve ◽  
Head And Neck Region ◽  
Histological Features ◽  
Nerve Sheath

AbstractNerve sheath tumours of the head and neck region mainly involve the eighth cranial nerve with only 4 per cent occurring in the paranasal sinuses. Only 32 cases of benign schwannomas occurring in the paranasal sinuses have been reported. We present a further case, review the current literature, and discuss the clinical details and specific histological features.

scholarly journals Teaching NeuroImages: Compression of the eighth cranial nerve causes vestibular paroxysmia

Neurology ◽  
2013 ◽  
Vol 80 (7) ◽  
pp. e77-e77 ◽  
Author(s):  
M. Strupp ◽  
S. von Stuckrad-Barre ◽  
T. Brandt ◽  
J. C. Tonn
Keyword(s):  
Cranial Nerve ◽  
Eighth Cranial Nerve ◽  
Vestibular Paroxysmia

Nasopharyngeal Mucormycotic Osteitis: A New Syndrome Characterized by Initial Presentation of Multiple Cranial Nerve Palsies

1980 ◽  
Vol 88 (2) ◽  
pp. 146-153 ◽  
Author(s):  
Mamdouh S. Bahna ◽  
Paul H. Ward ◽  
Horst R. Konrad
Keyword(s):  
Cranial Nerve ◽  
Clinical Syndrome ◽  
Review Of The Literature ◽  
Eighth Cranial Nerve ◽  
Nerve Paralysis ◽  
Cranial Nerve Paralysis ◽  
Biopsy Specimens ◽  
Cranial Nerve Palsies ◽  
Base Of The Skull ◽  
Multiple Cranial Nerve

Rhinocerebral mucormycosis, a highly lethal fungal infection of the head and neck, is commonly recognized by its classic appearance. Two cases of this newly recognized clinical syndrome with isolated unilateral peripheral cranial nerve V, VI, VII, IX, X, XI, and XII palsies and initial sparing of the eighth cranial nerve are presented. Examination revealed that each patient had ulceration of the nasopharynx and osteitis of the base of the skull. Nose, orbits, paranasal sinuses, and intracranial nervous systems were initially spared. The cause of this obscure cranial nerve paralysis was diagnosed from biopsy specimens of the nasopharyngeal tissues and the demonstration of nonseptate hyphae. Review of the literature did not indicate that this syndrome had previously been recognized. The name nasopharyngeal mucormycotic osteitis is suggested.

Superficial siderosis causing retrolabyrinthine involvement in both cochlear and vestibular branches of the eighth cranial nerve

2006 ◽  
Vol 126 (9) ◽  
pp. 997-1000 ◽  
Author(s):  
Munetaka Ushio ◽  
Shinichi Iwasaki ◽  
Keiko Sugasawa ◽  
Toshihisa Murofushi
Keyword(s):  
Cranial Nerve ◽  
Superficial Siderosis ◽  
Eighth Cranial Nerve
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