Olfactory receptor gene expression in tiger salamander olfactory epithelium

2004 ◽  
Vol 474 (3) ◽  
pp. 453-467 ◽  
Author(s):  
James E. Marchand ◽  
Xinhai Yang ◽  
Dona Chikaraishi ◽  
Jurgen Krieger ◽  
Heinz Breer ◽  
...  
Keyword(s):  
Gene Expression ◽  
Olfactory Epithelium ◽  
Olfactory Receptor ◽  
Receptor Gene ◽  
Tiger Salamander ◽  
Olfactory Receptor Gene ◽  
Receptor Gene Expression

Allelic inactivation regulates olfactory receptor gene expression

Cell ◽  
1994 ◽  
Vol 78 (5) ◽  
pp. 823-834 ◽  
Author(s):  
Andrew Chess ◽  
Itamar Simon ◽  
Howard Cedar ◽  
Richard Axel
Keyword(s):  
Gene Expression ◽  
Olfactory Receptor ◽  
Receptor Gene ◽  
Olfactory Receptor Gene ◽  
Receptor Gene Expression

scholarly journals Profiling of Olfactory Receptor Gene Expression in Whole Human Olfactory Mucosa

PLoS ONE ◽  
2014 ◽  
Vol 9 (5) ◽  
pp. e96333 ◽  
Author(s):  
Christophe Verbeurgt ◽  
Françoise Wilkin ◽  
Maxime Tarabichi ◽  
Françoise Gregoire ◽  
Jacques E. Dumont ◽  
...  
Keyword(s):  
Gene Expression ◽  
Olfactory Receptor ◽  
Receptor Gene ◽  
Olfactory Mucosa ◽  
Olfactory Receptor Gene ◽  
Human Olfactory Mucosa ◽  
Receptor Gene Expression

scholarly journals Epigenetic regulation of olfactory receptor gene expression by the Myb-MuvB/dREAM complex

2012 ◽  
Vol 26 (22) ◽  
pp. 2483-2498 ◽  
Author(s):  
C. K. Sim ◽  
S. Perry ◽  
S. K. Tharadra ◽  
J. S. Lipsick ◽  
A. Ray
Keyword(s):  
Gene Expression ◽  
Epigenetic Regulation ◽  
Olfactory Receptor ◽  
Receptor Gene ◽  
Olfactory Receptor Gene ◽  
Receptor Gene Expression

Spatially Organized Response Zones in Rat Olfactory Epithelium

1997 ◽  
Vol 77 (4) ◽  
pp. 1950-1962 ◽  
Author(s):  
John W. Scott ◽  
Donna E. Shannon ◽  
Jeff Charpentier ◽  
Lisa M. Davis ◽  
Craig Kaplan
Keyword(s):  
Gene Expression ◽  
Functional Groups ◽  
Olfactory Epithelium ◽  
Olfactory Receptor ◽  
Receptor Gene ◽  
Chemical Properties ◽  
Receptor Expression ◽  
Response Distribution ◽  
Chemical Structures ◽  
Four Electrodes

Scott, John W., Donna E. Shannon, Jeff Charpentier, Lisa M. Davis, and Craig Kaplan. Spatially organized response zones in rat olfactory epithelium. J. Neurophysiol. 77: 1950–1962, 1997. Electroolfactogram recordings were made with a four-electrode assembly from the olfactory epithelium overlying the endoturbinate bones facing the nasal septum. In this study we tested whether odors of different chemical structures produce maximal responses along longitudinally oriented regions following the olfactory receptor gene expression zones described in the literature. The distribution of responses along the dorsal-to-ventral direction of this epithelium (i.e., across the expression zones) was tested in two types of experiments. In one, four electrodes were fixed along the dorsal-to-ventral axis of one turbinate bone. In the other, four electrodes were placed in corresponding positions on four turbinate bones and moved together up toward the top of the bone. These experiments compared the odorants limonene and α-terpinene, which are simple hydrocarbons, with carvone and menthone, which differ from the hydrocarbons by the presence of ketone groups. All responses were standardized to an amyl acetate or ethyl butyrate standard. The responses to limonene and α-terpinene were often larger for the ventral electrodes. The responses to carvone and menthone were largest for the dorsal electrodes. Intermediate electrodes gave responses that were intermediate in amplitude for these odors. The possibility that direction of air flow caused the observed response distributions was directly tested in experiments with odor nozzles placed in two positions. The relatively larger dorsal responses to carvone and relatively larger ventral responses to limonene were present despite odor nozzle position. We conclude that the responses to this set of odors vary systematically in a fashion parallel to the four gene expression zones. The odorant property that governs this response distribution may be related to the presence of oxygen-containing functional groups. Certain odors evoked larger responses at the intermediate electrode sites than at other sites. Cineole was the best example of this effect. This observation shows that not all oxygen-containing functional groups produce the same effect. Although we cannot exclude other possible mechanisms, these three response gradients may be produced by the four receptor expression zones described for many of the putative olfactory receptor genes. Therefore many of the receptors in each zone may share common properties. It remains to be determined whether this zonal input is significant in central odor processing. However, the correlation of odor chemical properties with the structure of receptor molecules in each zone may provide significant leads to structure-function relationships in vertebrate olfaction.

A zonal organization of odorant receptor gene expression in the olfactory epithelium

Cell ◽  
1993 ◽  
Vol 73 (3) ◽  
pp. 597-609 ◽  
Author(s):  
Kerry J. Ressler ◽  
Susan L. Sullivan ◽  
Linda B. Buck
Keyword(s):  
Gene Expression ◽  
Olfactory Epithelium ◽  
Odorant Receptor ◽  
Receptor Gene ◽  
Zonal Organization ◽  
Receptor Gene Expression

scholarly journals Activity-Dependent Modulation of Odorant Receptor Gene Expression in the Mouse Olfactory Epithelium

PLoS ONE ◽  
2013 ◽  
Vol 8 (7) ◽  
pp. e69862 ◽  
Author(s):  
Shaohua Zhao ◽  
Huikai Tian ◽  
Limei Ma ◽  
Ying Yuan ◽  
C. Ron Yu ◽  
...  
Keyword(s):  
Gene Expression ◽  
Olfactory Epithelium ◽  
Odorant Receptor ◽  
Receptor Gene ◽  
Activity Dependent ◽  
Receptor Gene Expression
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