Cochlear electrical stimulation: Influence of age of implantation on Fos immunocytochemical reactions in inferior colliculi and dorsal cochlear nuclei of the rat

2001 ◽  
Vol 438 (2) ◽  
pp. 226-238 ◽  
Author(s):  
Wei-Chung Hsu ◽  
Antonio Campos-Torres ◽  
Frederic Portier ◽  
Eric Lecain ◽  
Thierry Van Den Abbeele ◽  
...  
Keyword(s):  
Electrical Stimulation ◽  
Cochlear Nuclei ◽  
Inferior Colliculi

Corticofugal Projection Inhibits the Auditory Thalamus Through the Thalamic Reticular Nucleus

2008 ◽  
Vol 99 (6) ◽  
pp. 2938-2945 ◽  
Author(s):  
Zhuo Zhang ◽  
Chun-Hua Liu ◽  
Yan-Qin Yu ◽  
Kenji Fujimoto ◽  
Ying-Shing Chan ◽  
...  
Keyword(s):  
Electrical Stimulation ◽  
Medial Geniculate Body ◽  
Thalamic Reticular Nucleus ◽  
Reticular Nucleus ◽  
Inhibitory Effects ◽  
Inhibitory Pathway ◽  
Inhibitory Postsynaptic Potentials ◽  
Medial Geniculate ◽  
Inferior Colliculi ◽  
Stimulation Of

Electrical stimulation of the auditory cortex (AC) causes both facilitatory and inhibitory effects on the medial geniculate body (MGB). The purpose of this study was to identify the corticofugal inhibitory pathway to the MGB. We assessed two potential circuits: 1) the cortico-colliculo-thalamic circuit and 2) cortico-reticulo-thalamic one. We compared intracellular responses of MGB neurons to electrical stimulation of the AC following bilateral ablation of the inferior colliculi (IC) or thalamic reticular nucleus (TRN) in anesthetized guinea pigs. Cortical stimulation with intact TRN could cause strong inhibitory effects on the MGB neurons. The corticofugal inhibition remained effective after bilateral IC ablation, but it was minimized after the TRN was lesioned with kainic acid. Synchronized TRN neuronal activity and MGB inhibitory postsynaptic potentials (IPSPs) were observed with multiple recordings. The results suggest that corticofugal inhibition traverses the corticoreticulothalamic pathway, indicating that the colliculi-geniculate inhibitory pathway is probably only for feedforward inhibition.

Cochleotopic fos immunoreactivity in cochlea and cochlear nuclei evoked by bipolar cochlear electrical stimulation

2000 ◽  
Vol 145 (1-2) ◽  
pp. 37-51 ◽  
Author(s):  
Hiromitsu Saito ◽  
Josef M Miller ◽  
Richard A Altschuler
Keyword(s):  
Electrical Stimulation ◽  
Cochlear Nuclei

Effects of Cochlear Nuclei Electrical Stimulation with Surface Brain Stem Implants in Nonhuman Primates

2008 ◽  
Vol 117 (3) ◽  
pp. 212-220 ◽  
Author(s):  
Manuel Manrique ◽  
Francisco Javier Cervera-Paz ◽  
Ana M. Insausti ◽  
Barry Nevison
Keyword(s):  
Electrical Stimulation ◽  
Brain Stem ◽  
Nonhuman Primates ◽  
Cochlear Nuclei

Averaged Evoked Potentials in Cats with Lesions of Auditory Pathway

1975 ◽  
Vol 18 (3) ◽  
pp. 420-429 ◽  
Author(s):  
Robert A. Goldenberg ◽  
Arthur J. Derbyshire
Keyword(s):  
Evoked Potentials ◽  
Blood Vessels ◽  
Evoked Potential ◽  
Round Window ◽  
Auditory Pathway ◽  
Wave Form ◽  
Evoked Responses ◽  
Cochlear Nuclei ◽  
Evoked Activity ◽  
Inferior Colliculi

Averaged evoked activity was recorded from needle electrodes placed at the vertex of the calvaria and adjacent to each bulla in anesthetized cats in response to click stimuli. The portion of the response from 0 to 10 msec was analyzed. Activity during the first 3 msec was greatly reduced on the side ipsilateral to a lesion involving destruction of the cochlea or section of the eighth nerve and its blood vessels. Activity after 4 msec was greatly reduced on the side ipsilateral to destruction of the cochlear nuclei. No effect was found with destruction of both inferior colliculi. The bulla-vertex evoked responses were also compared to those recorded from the round window. The results support the premise that change in the wave-form of the early evoked potential can be used to determine site of loss of acoustic information along the auditory pathway.

Auditory Brainstem Implantation: Anatomy and Approaches

2015 ◽  
Vol 11 (2) ◽  
pp. 306-321 ◽  
Author(s):  
Noritaka Komune ◽  
Kaan Yagmurlu ◽  
Satoshi Matsuo ◽  
Koichi Miki ◽  
Hiroshi Abe ◽  
...  
Keyword(s):  
Inferior Colliculus ◽  
Neurofibromatosis Type ◽  
Auditory Brainstem ◽  
Electrode Placement ◽  
Auditory Pathways ◽  
Cochlear Nuclei ◽  
Endoscopic Assistance ◽  
Inferior Collicular ◽  
Dissection Technique ◽  
Inferior Colliculi

Abstract BACKGROUND Auditory brainstem implantation at the cochlear nuclei used mainly for neurofibromatosis type 2 patients with bilateral loss of the cochlear nerves has more recently been extended to the inferior colliculus. OBJECTIVE To examine the microsurgical and endoscopic anatomy of the cochlear nuclei and inferior colliculus as seen through the translabyrinthine and retrosigmoid approaches used for cochlear nuclei and inferior collicular implantation. METHODS Ten cerebellopontine angles of formalin-fixed adult cadaveric heads were examined with the aid of the surgical microscope and endoscope. The ascending auditory pathways between the cochlear nuclei and inferior colliculi and above were examined by the fiber dissection technique. RESULTS Both the translabyrinthine and retrosigmoid routes provide sufficient exposure for concurrent tumor removal and implantation at either the cochlear nuclei or inferior colliculus. The position of the inferior colliculus in the auditory pathways and its accessibility in the infratentorial supracerebellar exposure directed through either the translabyrinthine or retrosigmoid approach makes it an alternative site for electrode placement if the cochlear nuclei are not functionally or structurally suitable for implantation. Endoscopic assistance may aid the exposure and electrode placement at either site. CONCLUSION The translabyrinthine or retrosigmoid approaches provide access to the cochlear nuclei for implantation and also to the inferior colliculus through the translabyrinthine or retrosigmoid infratentorial supracerebellar route. The endoscope may aid in exposing either site.

Acute Study on the Neuronal Excitablility of the Cochlear Nuclei of the Guinea Pig Following Electrical Stimulation

1997 ◽  
Vol 117 (3) ◽  
pp. 363-375 ◽  
Author(s):  
Xuguang Liu ◽  
Greg McPhee ◽  
H. Lee Seldon ◽  
Graeme M. Clark
Keyword(s):  
Electrical Stimulation ◽  
Guinea Pig ◽  
Cochlear Nuclei ◽  
Acute Study

The “KIMWIPE” Effect in Ultra-Thin Cryosections

1985 ◽  
Vol 43 ◽  
pp. 458-459
Author(s):  
I. Taylor ◽  
P. Ingram ◽  
J.R. Sommer
Keyword(s):  
Skeletal Muscle ◽  
Electrical Stimulation ◽  
Muscle Fibers ◽  
Ice Crystals ◽  
Crystal Formation ◽  
Ice Crystal ◽  
Thin Sections ◽  
Skeletal Muscle Fibers ◽  
Freeze Dried ◽  
Ice Crystal Formation

In studying quick-frozen single intact skeletal muscle fibers for structural and microchemical alterations that occur milliseconds, and fractions thereof, after electrical stimulation, we have developed a method to compare, directly, ice crystal formation in freeze-substituted thin sections adjacent to all, and beneath the last, freeze-dried cryosections. We have observed images in the cryosections that to our knowledge have not been published heretofore (Figs.1-4). The main features are that isolated, sometimes large regions of the sections appear hazy and have much less contrast than adjacent regions. Sometimes within the hazy regions there are smaller areas that appear crinkled and have much more contrast. We have also observed that while the hazy areas remain still, the regions of higher contrast visibly contract in the beam, often causing tears in the sections that are clearly not caused by ice crystals (Fig.3, arrows).

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