Thalamo-cortical connections of areas 3a and M1 in marmoset monkeys

2001 ◽  
Vol 435 (3) ◽  
pp. 291-310 ◽  
Author(s):  
Kelly J. Huffman ◽  
Leah Krubitzer
2012 ◽  
Vol 295 (5) ◽  
pp. 800-821 ◽  
Author(s):  
Lisa A. de la Mothe ◽  
Suzanne Blumell ◽  
Yoshinao Kajikawa ◽  
Troy A. Hackett

2006 ◽  
Vol 496 (1) ◽  
pp. 27-71 ◽  
Author(s):  
Lisa A. de la Mothe ◽  
Suzanne Blumell ◽  
Yoshinao Kajikawa ◽  
Troy A. Hackett

Author(s):  
Sarah F. Beul ◽  
Alexandros Goulas ◽  
Claus C. Hilgetag

AbstractStructural connections between cortical areas form an intricate network with a high degree of specificity. Many aspects of this complex network organization in the adult mammalian cortex are captured by an architectonic type principle, which relates structural connections to the architectonic differentiation of brain regions. In particular, the laminar patterns of projection origins are a prominent feature of structural connections that varies in a graded manner with the relative architectonic differentiation of connected areas in the adult brain. Here we show that the architectonic type principle is already apparent for the laminar origins of cortico-cortical projections in the immature cortex of the macaque monkey. We find that prenatal and neonatal laminar patterns correlate with cortical architectonic differentiation, and that the relation of laminar patterns to architectonic differences between connected areas is not substantially altered by the complete loss of visual input. Moreover, we find that the degree of change in laminar patterns that projections undergo during development varies in proportion to the relative architectonic differentiation of the connected areas. Hence, it appears that initial biases in laminar projection patterns become progressively strengthened by later developmental processes. These findings suggest that early neurogenetic processes during the formation of the brain are sufficient to establish the characteristic laminar projection patterns. This conclusion is in line with previously suggested mechanistic explanations underlying the emergence of the architectonic type principle and provides further constraints for exploring the fundamental factors that shape structural connectivity in the mammalian brain.


Reproduction ◽  
2010 ◽  
Vol 139 (5) ◽  
pp. 923-930 ◽  
Author(s):  
Nicola Beindorff ◽  
Almuth Einspanier

In early pregnant primates, relaxin (RLX) is highly upregulated within the corpus luteum (CL), suggesting that RLX may have an important role in the implantation of the blastocyst. Therefore, the aim of the present study was to investigate the local effects of RLX and gonadotrophins on the maintenance of the CL using anin vitromicrodialysis system. CLs of common marmoset monkeys were collected by luteectomy during different stages of the luteal phase and early pregnancy. Each CL was perfused with either Ringer's solution alone or Ringer's solution supplemented with either porcine RLX (250, 500 and 1000 ng/ml) or gonadotrophins (50 IU/ml). Application of RLX provoked a significant luteal response of progesterone (P4) and oestradiol (E2) secretions during the mid-luteal phase (500 ng/ml: P454±42%, E224±11%; 1000 ng/ml: E216±13%), and especially during the late luteal phase (250 ng/ml: P453±10%; 500 ng/ml: P444±15%; 1000 ng/ml: P462±15%, E218±7%). The effects of RLX on steroid secretion were irrespective of the RLX dosages. While treatment with human chorionic gonadotrophin did not affect luteal steroid or RLX secretion, the application of FSH resulted in a significant increase in the secretion of both P4(20±8%) and E2(37±28%), and a prominent rise in RLX during early pregnancy. In conclusion, our results demonstrate that RLX and FSH have a luteotrophic function in the marmoset monkeys; moreover, FSH has a function beyond its traditional role just as a follicle-stimulating hormone.


2015 ◽  
Vol 67 (1) ◽  
pp. 41-51 ◽  
Author(s):  
Yui Suzuki ◽  
Itaru Yamaguchi ◽  
Kensuke Myojo ◽  
Naoya Kimoto ◽  
Minami Imaizumi ◽  
...  

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