scholarly journals TTF-1 and Napsin A double stain

2011 ◽  
Vol 119 (2) ◽  
pp. 127-133 ◽  
Author(s):  
Nazneen Fatima ◽  
Cynthia Cohen ◽  
Diane Lawson ◽  
Momin T. Siddiqui
Keyword(s):  
Napsin A ◽  
Double Stain

scholarly journals Napsin-A, TTF-1, EGFR, and ALK Status Determination in Lung Primary and Metastatic Mucin-Producing Adenocarcinomas

2014 ◽  
Vol 22 (5) ◽  
pp. 401-407 ◽  
Author(s):  
Giulio Rossi ◽  
Alberto Cavazza ◽  
Luisella Righi ◽  
Giuliana Sartori ◽  
Alessandra Bisagni ◽  
...  
Keyword(s):  
Napsin A

Biology of the tubercle bacillus

1926 ◽  
Vol 22 (4) ◽  
pp. 380-385
Author(s):  
B. L. Mazur
Keyword(s):  
Aqueous Solution ◽  
Methylene Blue ◽  
Alcoholic Solution ◽  
Blue Color ◽  
Tubercle Bacillus ◽  
Double Stain

Long before the discovery of the pathogen tbc, botanists used a double color: they stained their preparations with an alkaline or alcoholic solution of methylene blue, and then again with an aqueous solution of Vesuvine. He was also aware of the fact that sometimes, with such a double stain, some parts of the preparation from the plant parenchyma lose their blue color and are colored in the color of Vesuvine.

Expressions of Thyroid Transcription Factor-1, Napsin A, p40, p63, CK5/6 and Desmocollin-3 in Non-Small Cell Lung Cancer, as Revealed by Imprint Cytology Using a Malinol-Based Cell-Transfer Technique

2015 ◽  
Vol 59 (6) ◽  
pp. 457-464 ◽  
Author(s):  
Toshiaki Kawai ◽  
Susumu Tominaga ◽  
Sadayuki Hiroi ◽  
Koji Kameda ◽  
Sho Ogata ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Small Cell ◽  
Imprint Cytology ◽  
Small Cell Lung ◽  
Thyroid Transcription Factor 1 ◽  
Thyroid Transcription Factor ◽  
Napsin A ◽  
Transcription Factor 1

Background: The introduction of new therapies has made it important to differentiate between adenocarcinoma and squamous cell carcinoma. To allow the use of various immunocytochemical stains on limited materials, we tried transferring cells from a given smear to multiple slides. Using touch-preparation samples of 215 surgically resected non-small cell lung carcinomas of confirmed histologic classification (adenocarcinoma,n = 101; squamous cell carcinoma,n = 114), we performed immunocytochemistry for thyroid transcription factor-1, napsin A, p40, p63, CK5/6 and desmocollin-3, and compared cytologic staining results with the corresponding resection. Methods: We examined: (a) the expressions of the above 6 antibodies on cells transferred from touch imprints of resected specimens, the extent of staining being considered positive if more than 5% of the area was stained, and (b) the sensitivity, specificity, positive predictive value and negative predictive value for each antibody. Results: The histologic corresponding rate with Papanicolaou staining was only 73%. Regarding the differentiation of adenocarcinoma from squamous cell carcinoma, the sensitivity and specificity for napsin A in adenocarcinoma were 80 and 97%, respectively, while those for p40 in squamous cell carcinoma were 84 and 98%, respectively. Conclusion: The immunocytochemical expressions of napsin A and p40 in imprint cytology seem to be of great utility for the accurate histological differentiation of lung cancers.

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