scholarly journals Reply to Are adjuvant radiotherapy outcomes really better in patients with early‐stage oral cavity squamous cell carcinoma?

Cancer ◽  
2018 ◽  
Vol 124 (23) ◽  
pp. 4578-4579 ◽  
Author(s):  
Eran Fridman ◽  
Shorook Na’ara ◽  
Ziv Gil
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Adjuvant Radiotherapy ◽  
Early Stage

scholarly journals Postoperative PET/CT and target delineation before adjuvant radiotherapy in patients with oral cavity squamous cell carcinoma

Head & Neck ◽  
2015 ◽  
Vol 38 (S1) ◽  
pp. E1285-E1293 ◽  
Author(s):  
Pinaki R. Dutta ◽  
Nadeem Riaz ◽  
Sean McBride ◽  
Luc G. Morris ◽  
Snehal Patel ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Adjuvant Radiotherapy ◽  
Target Delineation ◽  
Pet Ct

Concurrent chemoradiotherapy compared with surgery and adjuvant radiotherapy for oral cavity squamous cell carcinoma

Head & Neck ◽  
2014 ◽  
Vol 37 (4) ◽  
pp. 518-523 ◽  
Author(s):  
Sinclair M. Gore ◽  
Anthony K. Crombie ◽  
Martin D. Batstone ◽  
Jonathan R. Clark
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Adjuvant Radiotherapy ◽  
Concurrent Chemoradiotherapy

scholarly journals Distribution of oral carcinoma case requiring radiotherapy in the Oral and Maxillofacial Surgery Clinics

2015 ◽  
Vol 27 (2) ◽  
Author(s):  
Dinda Tegar Jelita ◽  
Lucky Riawan ◽  
Herman Hambali
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Adjuvant Radiotherapy ◽  
Maxillofacial Surgery ◽  
Oral Carcinoma ◽  
Oral And Maxillofacial Surgery ◽  
Age Group ◽  
Common Area

Introduction: Carcinoma is a highly malignant tumour of epithelium that occurred in the oral cavity. One of the most common therapies given is radiotherapy, with healing, adjuvant, and palliative intentions. This research was aimed to discover the distribution of oral carcinoma requiring radiotherapy. Methods: This study was a retrospective, descriptive method. Samples were taken from the medical record of patients with oral cavity carcinoma requiring radiotherapy at the Oral and Maxillofacial Surgery Clinics of Hasan Sadikin Hospital, Bandung, of January 2006–December 2010. Results: This study indicated that as many as 23 (20.9%) cases of oral carcinoma requiring radiotherapy from a total of 110 oral carcinoma cases in that period. Type of radiotherapy most frequently found was adjuvant radiotherapy, by 14 (60.8%) cases. The most frequent type of oral carcinoma case requiring radiotherapy was squamous cell carcinoma, by 12 (52.1%) cases. Tongue become the most common area of oral carcinoma requiring radiotherapy, by 7 (30.4%) cases. Oral carcinoma case requiring radiotherapy was most frequently found in men by 14 (60.8%) cases. The age group of 41-50 was become the majority by 7 (30.4%) cases from all of the oral carcinoma case requiring radiotherapy. Conclusion: Distribution of oral carcinoma case requiring radiotherapy in the Oral and Maxillofacial Surgery Clinics of Hasan Sadikin Hospital is found in as many as 23 (20.9%) cases. Most frequent radiotherapy given is adjuvant radiotherapy (14 (60.8%) cases). The most frequent type of oral carcinoma case requiring radiotherapy is squamous cell carcinoma (12 (52.1%) cases). The most common area of oral carcinoma requiring radiotherapy is tongue (7 (30.4%) cases). Oral carcinoma case requiring radiotherapy was most frequently found in men (14 (60.8%) cases). The age group of 41-50 is the majority age suffered from disease (7 (30.4%) cases).

scholarly journals Role of Depth of Invasion in Evaluation and Management of Early-stage Oral Cavity Squamous Cell Carcinoma

2017 ◽  
Vol 8 (2) ◽  
pp. 84-88
Author(s):  
Bahbak Shariat-Madar ◽  
Jeffrey C Liu
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Early Stage ◽  
Lymph Node Staging ◽  
Depth Of Invasion ◽  
Disease Free

ABSTRACT Aim To evaluate the existing body of literature and impact of depth of invasion (DOI) in early-stage oral cavity squamous cell carcinoma (OCSCC) and its role in predicting occult cervical lymph node metastases. Background The prognosis for early-stage T1 to T2 disease OCSCC is relatively poor compared with other mucosal subsites within the head and neck. Primary tumor DOI can help prognosticate high-risk tumors for additional treatment. Review results There are unequivocal management implications in the literature demonstrating a role for elective neck dissection in early-stage OCSCC based on DOI. Following appropriate patient selection, there may be a role for sentinel lymph node biopsy in regional lymph node staging in early-stage OCSCC. Conclusion There are a multitude of studies demonstrating novel strategies to appropriately treat early-stage OCSCC, which are increasingly becoming standard of care. These strategies are altering the overall and disease-free survival of early-stage OCSCC. Despite advances, locoregional recurrence remains a challenge in this disease. Clinical significance Herein, the authors highlight a number of advances in the management of early-stage OCSCC as described in the literature, which are having an impact on disease-free and overall survival. How to cite this article Shariat-Madar B, Liu JC. Role of Depth of Invasion in Evaluation and Management of Early-stage Oral Cavity Squamous Cell Carcinoma. Int J Head Neck Surg 2017;8(2):84-88.

scholarly journals To evaluate disparity between clinical and pathological tumor-node-metastasis staging in oral cavity squamous cell carcinoma patients and its impact on overall survival: An institutional study

2015 ◽  
Vol 04 (04) ◽  
pp. 183-185 ◽  
Author(s):  
Karan Gupta ◽  
Naresh K Panda ◽  
Jaimanti Bakshi ◽  
Ashim Das
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Early Stage ◽  
Tnm Staging ◽  
Advanced Stage ◽  
Tumor Node Metastasis ◽  
Node Metastasis ◽  
N Stage

Abstract Background: Accurate clinical staging is important for patient counseling, treatment planning, prognostication, and rational design of clinical trials. In head and neck squamous cell carcinoma, discrepancy between clinical and pathological staging has been reported. Objective: To evaluate any disparity between clinical and pathological tumor-node-metastasis (TNM) staging in oral cavity squamous cell carcinoma (OCSCC) patients and any impact of the same on survival. Materials and Methods: Retrospective chart review from year 2007 to 2013, at a tertiary care center. Statistical Analysis: All survival analyses were performed using SPSS for Windows version 15 (Chicago, IL, USA). Disease-free survival curves were generated using Kaplan-Meier algorithm. Results: One hundred and twenty-seven patients with OCSCC were analyzed. Seventy-nine (62.2%) were males and 48 (37.8%) females with a mean age at presentation 43.6 years (29-79 years). The highest congruence between clinical and pathological T-staging seen for clinical stage T1 and T4 at 76.9% and 73.4% with pathological T-stage. Similarly, the highest congruence between clinical and pathological N-stage seen for clinical N0 and N3 at 86.4% and 91.7% with pathological N-stage. Of clinically early stage patients, 67.5% remained early stage, and 32.5% were upstaged to advanced stage following pathological analysis. Of the clinically advanced stage patients, 75% remained advanced, and 25% were pathologically downstaged. This staging discrepancy did not significantly alter the survival. Conclusion: Some disparity exists in clinical and pathological TNM staging of OCSCC, which could affect treatment planning and survival of patients. Hence, more unified and even system of staging for the disease is required for proper decision-making.

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