scholarly journals Comparative effectiveness of first-line radiofrequency ablation versus surgical resection and transplantation for patients with early hepatocellular carcinoma

Cancer ◽  
2017 ◽  
Vol 123 (10) ◽  
pp. 1817-1827 ◽  
Author(s):  
Onur C. Kutlu ◽  
Jennifer A. Chan ◽  
Thomas A. Aloia ◽  
Yun S. Chun ◽  
Ahmed O. Kaseb ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Radiofrequency Ablation ◽  
Surgical Resection ◽  
Comparative Effectiveness ◽  
First Line ◽  
Early Hepatocellular Carcinoma

scholarly journals Meta-analysis of surgical resection and radiofrequency ablation for early hepatocellular carcinoma

2012 ◽  
Vol 10 (1) ◽  
pp. 163 ◽  
Author(s):  
Gang Xu ◽  
Fu-zhen Qi ◽  
Jian-huai Zhang ◽  
Guo-feng Cheng ◽  
Yong Cai ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Radiofrequency Ablation ◽  
Surgical Resection ◽  
Meta Analysis ◽  
Early Hepatocellular Carcinoma

Percutaneous radiofrequency ablation compared with surgical resection in the treatment of early hepatocellular carcinoma

2018 ◽  
Vol 37 (3) ◽  
pp. 286
Author(s):  
AshrafM Abd El-Kader ◽  
HazemE Ali ◽  
MagdyA Gad ◽  
BadawyA Abdel Aziz ◽  
Sharaf ElsayedAli Hassanien ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Radiofrequency Ablation ◽  
Surgical Resection ◽  
Percutaneous Radiofrequency Ablation ◽  
Early Hepatocellular Carcinoma

scholarly journals When to Perform Surgical Resection or Radiofrequency Ablation for Early Hepatocellular Carcinoma?

Medicine ◽  
2015 ◽  
Vol 94 (43) ◽  
pp. e1808 ◽  
Author(s):  
Po-Hong Liu ◽  
Chia-Yang Hsu ◽  
Yun-Hsuan Lee ◽  
Cheng-Yuan Hsia ◽  
Yi-Hsiang Huang ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Radiofrequency Ablation ◽  
Surgical Resection ◽  
Early Hepatocellular Carcinoma

scholarly journals A comparison of prognoses between surgical resection and radiofrequency ablation therapy for patients with hepatocellular carcinoma and esophagogastric varices

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Cheng-Yi Wei ◽  
Gar-Yang Chau ◽  
Ping-Hsien Chen ◽  
Chien-An Liu ◽  
Yi-Hsiang Huang ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Radiofrequency Ablation ◽  
Surgical Resection ◽  
Proportional Hazards Model ◽  
Cox Proportional Hazards ◽  
Cox Proportional Hazards Model ◽  
Line Treatment ◽  
First Line ◽  
Esophagogastric Varices ◽  
First Line Treatment

Abstract There has been insufficient investigation of the differences in long-term outcomes between surgical resection (SR) and radiofrequency ablation (RFA) among patients with hepatocellular carcinoma (HCC) and esophagogastric varices (EGV). We retrospectively enrolled 251 patients with treatment-naïve HCC and EGV who underwent SR or RFA as a first-line treatment. Prognostic factors were analyzed using a Cox proportional hazards model. A total of 68 patients underwent SR, and the remaining 183 patients received RFA. Patients who underwent SR were younger, had better liver functional reserves, and had larger tumors. After a median follow-up duration of 45.1 months, 151 patients died. The cumulative 5-year overall survival (OS) rate was significantly higher among patients who underwent SR than those treated with RFA (66.7% vs. 36.8%, p < 0.001). Multivariate analysis showed that age > 65 years, multiple tumors, RFA, albumin bilirubin grade > 1, and the occurrence of major peri-procedural morbidity were the independent risk factors that are predictive of poor OS. In conclusion, SR could be recommended as a first-line treatment modality for HCC patients with EGV if the patients are carefully selected and liver function is well preserved.

Comparison of Transarterial Chemoembolization Combined with Radiofrequency Ablation Therapy versus Surgical Resection for Early Hepatocellular Carcinoma

2018 ◽  
Vol 84 (2) ◽  
pp. 282-288
Author(s):  
Peng-Sheng Yi ◽  
Min Huang ◽  
Ming Zhang ◽  
Liangliang Xu ◽  
Ming-Qing Xu
Keyword(s):  
Hepatocellular Carcinoma ◽  
Radiofrequency Ablation ◽  
Surgical Resection ◽  
Transarterial Chemoembolization ◽  
Combined Therapy ◽  
Cochrane Library ◽  
Term Survival ◽  
Early Hepatocellular Carcinoma ◽  
Local Progression ◽  
Early Hcc

Both radiofrequency ablation (RFA) and surgical resection (SR) are radical treatment recommended for early hepatocellular carcinoma (HCC). Transarterial chemoembolization (TACE) is a palliative treatment for intermediate HCC, and TACE1RFA combined therapy is considered superior to TACE or RFA alone for management of early HCC. This systematic review compared the efficacy and safety of TACE1RFA combined therapy with SR for early HCC. Web of Science, PubMed, EMBASE, and the Cochrane Library were searched for literatures related with our topic. The primary endpoint was overall survival (OS), and the secondary endpoint was the recurrence-free survival (RFS) rate; safety was measured by the rate of major complications. The effect sizes of OS, RFS, and local progression rates were expressed by odds ratio (OR), while the effect size of complications was presented using relative risk. TACE1RFA combined therapy and SR had a similar 1-year OS rate [OR: 1.84; 95% confidence interval (CI): 0.82, 4.14; P > 0.05], 3-year OS rate (OR: 0.84; 95% CI: 0.43, 1.67; P > 0.05), 1-year RFS rate (OR: 0.77; 95% CI: 0.53, 1.11; P > 0.05), and 3-year RFS rate (OR: 0.88; 95% CI: 0.48, 1.42; P > 0.05) for early HCC. However, the 5-year OS rate (OR: 0.54; 95% CI: 0.40, 0.73; P < 0.05) and 5-year RFS rate (OR: 0.49; 95% CI: 0.27, 0.90; P < 0.05) were lower in patients with TACE1RFA than in those with SR. SR is associated with better long-term survival outcomes and a lower recurrence rate than TACE1RFA for patients with early HCC and is the optimal choice for patients with early HCC.

Leberzellkarzinom – Radiofrequenzablation: Welches Bildgebungsverfahren ist effektiver?

2019 ◽  
Vol 24 (04) ◽  
pp. 163-164
Author(s):  
Cornelia Fietz
Keyword(s):  
Computed Tomography ◽  
Hepatocellular Carcinoma ◽  
Radiofrequency Ablation ◽  
Comparative Effectiveness ◽  
Percutaneous Radiofrequency Ablation ◽  
Ultrasound Guided ◽  
Medicare Patients ◽  
Us Dollar

Huo J et al. Comparative Effectiveness of Computed Tomography-Versus Ultrasound-Guided Percutaneous Radiofrequency Ablation Among Medicare Patients 65 Years of Age or Older With Hepatocellular Carcinoma. Value Health 2019; 22(3):284–292 Die Inzidenz des Leberzellkarzinoms hat sich in den letzen 20 Jahren mehr als verdoppelt. 2018 wurden in den USA mehr als 31 600 neue Fälle registriert, knapp die Hälfte dieser Patienten war älter als 65 Jahre. Die damit verbundenen jährlichen Kosten werden auf 455 Millionen US Dollar geschätzt. Für fortgeschrittene, inoperable Fälle steht die Radiofrequenzablation als Therapieoption zur Verfügung, die Ultraschall- oder Computertomographie-gestützt durchgeführt werden kann. Die Autoren vergleichen die Effektivität beider Bildgebungstechniken für das Verfahren.

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