scholarly journals Long-term follow-up of patients treated with neoadjuvant chemotherapy and radiotherapy for large, extremity soft tissue sarcomas

Cancer ◽  
2011 ◽  
Vol 118 (15) ◽  
pp. 3758-3765 ◽  
Author(s):  
John T. Mullen ◽  
Wendy Kobayashi ◽  
Jing Jing Wang ◽  
David C. Harmon ◽  
Edwin Choy ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Neoadjuvant Chemotherapy ◽  
Soft Tissue Sarcomas ◽  
Long Term Follow Up

Long-term follow-up of patients treated with neoadjuvant chemotherapy and radiotherapy for large extremity soft tissue sarcomas.

2010 ◽  
Vol 28 (15_suppl) ◽  
pp. 10022-10022
Author(s):  
J. T. Mullen ◽  
W. Kobayashi ◽  
D. C. Harmon ◽  
E. Choy ◽  
F. Hornicek ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Neoadjuvant Chemotherapy ◽  
Soft Tissue Sarcomas ◽  
Long Term Follow Up

Prognostic factors associated with long-term survival for retroperitoneal sarcoma: implications for management.

1997 ◽  
Vol 15 (8) ◽  
pp. 2832-2839 ◽  
Author(s):  
M J Heslin ◽  
J J Lewis ◽  
E Nadler ◽  
E Newman ◽  
J M Woodruff ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Sarcomas ◽  
Term Survival ◽  
Long Term Survival ◽  
Increased Risk ◽  
Long Term Follow Up ◽  
Disease Free ◽  
Patterns Of Recurrence

PURPOSE Retroperitoneal soft tissue sarcomas are rare tumors. Studies characterizing long-term follow-up and patterns of recurrence are limited. The purpose of this analysis is to identify patterns of recurrence and prognostic factors associated with long-term survival after resection of retroperitoneal soft tissue sarcomas. METHODS Between July 1, 1982, and June 30, 1990, 198 adult patients were identified from our prospective soft tissue sarcoma database carrying the diagnosis of retroperitoneal soft tissue sarcoma who were eligible for > or = 5 years of follow-up. Of these, 48 patients (25%) were documented to be alive > or = 5 years from the time of operation. Statistical analysis was by log-rank or Wilcoxon test for univariate analysis. Multivariate analysis was by the Cox model. RESULTS The recurrence rate during the follow-up period was approximately 5% per year from the time of initial operation. Of the patients who were disease-free for > or = 5 years from initial surgery, 40% recurred by 10 years. Radiation therapy was the only factor significant (P = .02) for a reduction in the risk of local recurrence. Age < or = 50 years and high-grade tumors were significant factors (P = .003 and .009, respectively) for an increased risk of distant metastasis. Incomplete gross resection was the only factor significant for an increased risk of tumor mortality (P = .003). CONCLUSION Complete surgical resection at the time of primary presentation is likely to afford the best chance for long-term survival. With long-term follow-up, it is clear that recurrence will continue to occur, and a 5-year disease-free interval is not a cure. Patients with an incomplete initial resection, age less than 50 years, and high-grade tumors are candidates for investigational adjuvant therapy.

Long-term Follow-up of Preoperative Bevacizumab and Radiation in Soft Tissue Sarcomas

2015 ◽  
Vol 93 (3) ◽  
pp. S28
Author(s):  
Y.L. Chen ◽  
S.S. Yoon ◽  
E. Choy ◽  
F.J. Hornicek ◽  
J.T. Mullen ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Sarcomas ◽  
Long Term Follow Up

Long-Term Follow-up of the First Randomized Trial Using Neoadjuvant Chemotherapy in Stage Ib Squamous Carcinoma of the Cervix: The Final Results

1997 ◽  
Vol 67 (1) ◽  
pp. 61-69 ◽  
Author(s):  
Juan E. Sardi ◽  
Adolfo Giaroli ◽  
Carlos Sananes ◽  
Marta Ferreira ◽  
Alejandro Soderini ◽  
...  
Keyword(s):  
Neoadjuvant Chemotherapy ◽  
Randomized Trial ◽  
Squamous Carcinoma ◽  
Stage Ib ◽  
Long Term Follow Up
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