scholarly journals Prognostic impact of insulin receptor expression on survival of patients with nonsmall cell lung cancer

Cancer ◽  
2011 ◽  
Vol 118 (9) ◽  
pp. 2454-2465 ◽  
Author(s):  
Jin-Soo Kim ◽  
Edward S. Kim ◽  
Diane Liu ◽  
J. Jack Lee ◽  
Luisa Solis ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Insulin Receptor ◽  
Cell Lung Cancer ◽  
Nonsmall Cell Lung Cancer ◽  
Receptor Expression ◽  
Prognostic Impact ◽  
Insulin Receptor Expression

scholarly journals Prognostic impact of CD73 and A2A adenosine receptor expression in non-small-cell lung cancer

Oncotarget ◽  
2017 ◽  
Vol 8 (5) ◽  
pp. 8738-8751 ◽  
Author(s):  
Yusuke Inoue ◽  
Katsuhiro Yoshimura ◽  
Nobuya Kurabe ◽  
Tomoaki Kahyo ◽  
Akikazu Kawase ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Adenosine Receptor ◽  
Small Cell ◽  
Receptor Expression ◽  
Prognostic Impact ◽  
Small Cell Lung ◽  
A2a Adenosine Receptor

scholarly journals Predictive and prognostic impact of primary tumor‐bearing lobe in nonsmall cell lung cancer patients treated with anti‐PD ‐1 therapy

2020 ◽  
Vol 147 (8) ◽  
pp. 2327-2334 ◽  
Author(s):  
Shinkichi Takamori ◽  
Kazuki Takada ◽  
Mototsugu Shimokawa ◽  
Taichi Matsubara ◽  
Naoki Haratake ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Patients ◽  
Cell Lung Cancer ◽  
Primary Tumor ◽  
Nonsmall Cell Lung Cancer ◽  
Prognostic Impact ◽  
Lung Cancer Patients ◽  
Tumor Bearing

scholarly journals Transferrin receptor expression in nonsmall cell lung cancer: Histopathologic and clinical correlates

Cancer ◽  
1996 ◽  
Vol 78 (1) ◽  
pp. 178-179 ◽  
Author(s):  
Paolo Carbognani ◽  
Michele Rusca ◽  
Antonello Romani ◽  
Lorenzo Spaggiari ◽  
Leonardo Cattelani ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cell Lung Cancer ◽  
Transferrin Receptor ◽  
Nonsmall Cell Lung Cancer ◽  
Receptor Expression ◽  
Clinical Correlates ◽  
Transferrin Receptor Expression

scholarly journals Biomarkers for efficacy of adjuvant chemotherapy following complete resection in NSCLC stages I–IIIA

2015 ◽  
Vol 24 (136) ◽  
pp. 340-355 ◽  
Author(s):  
Sandra Wallerek ◽  
Jens Benn Sørensen
Keyword(s):  
Lung Cancer ◽  
Adjuvant Chemotherapy ◽  
Cell Lung Cancer ◽  
Current Knowledge ◽  
Nonsmall Cell Lung Cancer ◽  
Chemotherapeutic Agents ◽  
Complete Resection ◽  
Prognostic Impact ◽  
Gene Profile ◽  
Nsclc Patients

Biomarkers may be useful when deciding which nonsmall cell lung cancer (NSCLC) patients may benefit from adjuvant chemotherapy following complete resection and which chemotherapeutic agents may be used preferably in individual patients in order to maximise survival.A literature search covering the period from 2003 to May, 2014 was conducted using PubMed and the following search terms: “non-small cell lung cancer”, “NSCLC”, “adjuvant chemotherapy”, “randomized”, “randomised”, “biomarkers”, “prognostic”, “predictive”. This review focuses on current knowledge of biomarkers for prognosis or efficacy of adjuvant treatment following complete resection in stage I–IIIA NSCLC patients.This review includes results on 18 different biomarkers and five gene profiles. A statistically significant prognostic impact was reported for: iNTR, TUBB3, RRM1, ERCC1, BRCA1, p53, MRP2, MSH2, TS, mucin, BAG-1, pERK1/2, pAkt-1, microRNA, TopIIA, 15-gene profile, 92-gene profile, 31-gene profile and 14-gene profile. A statistically significant predictive impact was reported for: ERCC1, p53, MSH2, p27, TUBB3, PARP1, ATM, 37-gene profile, 31-gene profile, 15-gene profile and 92-gene profile.Uncertainties regarding the optimal analysis method and cut-off levels for the individual markers may blur the prognostic or predictive signals. None of the possible predictive markers have been validated in prospective trials. Thus, there are no biomarkers ready to use in an adjuvant setting in NSCLC.

scholarly journals Prognostic impact of Notch ligands and receptors in nonsmall cell lung cancer

Cancer ◽  
2010 ◽  
Vol 116 (24) ◽  
pp. 5676-5685 ◽  
Author(s):  
Tom Donnem ◽  
Sigve Andersen ◽  
Khalid Al-Shibli ◽  
Samer Al-Saad ◽  
Lill-Tove Busund ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cell Lung Cancer ◽  
Nonsmall Cell Lung Cancer ◽  
Prognostic Impact ◽  
Notch Ligands

scholarly journals Independent and tissue-specific prognostic impact of miR-126 in nonsmall cell lung cancer

Cancer ◽  
2011 ◽  
Vol 117 (14) ◽  
pp. 3193-3200 ◽  
Author(s):  
Tom Donnem ◽  
Kenneth Lonvik ◽  
Katrine Eklo ◽  
Thomas Berg ◽  
Sveinung W. Sorbye ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cell Lung Cancer ◽  
Nonsmall Cell Lung Cancer ◽  
Prognostic Impact ◽  
Tissue Specific
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